Eva Hörmanseder
@evahoermanseder.bsky.social
Science at work / Mom, Gardener & Knitter 🧶 at home
Scientific Grant Coordinator at IMP Vienna
Love for Development, Reprogramming, Epigenetics and Xenopus 🐸
Scientific Grant Coordinator at IMP Vienna
Love for Development, Reprogramming, Epigenetics and Xenopus 🐸
Pinned
nature.com
We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it:
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Reposted by Eva Hörmanseder
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
January 9, 2026 at 10:54 AM
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session.
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Free registration, until Jan 15th
Don’t miss it!
👉https://training.institut-curie.org/courses/Genome-Dynamics-2026
@institutcurie.bsky.social
Reposted by Eva Hörmanseder
Now final version out: Our manuscript connecting histone modifications with metabolism: How H4K16 acylations regulate inter +intranucleosomal interactions and confer resilience to metabolic challenges in vivo. Thanks to the team+ @sandrani.bsky.social
Enjoy 👇👇 www.cell.com/molecular-ce...
Enjoy 👇👇 www.cell.com/molecular-ce...
H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations
Nitsch et al. show that short-chain acylations of histone H4K16, acetylation (C2),
propionylation (C3), and butyrylation (C4) modulate chromatin structure in vitro.
These effects can translate in vivo...
www.cell.com
January 9, 2026 at 12:22 PM
Now final version out: Our manuscript connecting histone modifications with metabolism: How H4K16 acylations regulate inter +intranucleosomal interactions and confer resilience to metabolic challenges in vivo. Thanks to the team+ @sandrani.bsky.social
Enjoy 👇👇 www.cell.com/molecular-ce...
Enjoy 👇👇 www.cell.com/molecular-ce...
Happy birthday to Xenbase! Our research would have not been possible without you and your fantastic community support 🤩
January 7, 2026 at 6:16 PM
Happy birthday to Xenbase! Our research would have not been possible without you and your fantastic community support 🤩
Reposted by Eva Hörmanseder
Our preprint "Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo" is on bioRxiv: www.biorxiv.org/content/10.6... . Amazing collaboration by @shenzhichen1999.bsky.social, Vincent Loubiere (@impvienna.bsky.social,@viennabiocenter.bsky.social),... (1/2)
Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo
Enhancers control tissue-specific gene expression across metazoans. Although deep learning has enabled enhancer prediction and design in mammalian cell lines and invertebrate systems, it remains uncle...
www.biorxiv.org
December 24, 2025 at 3:06 PM
Our preprint "Predictive design of tissue-specific mammalian enhancers that function in vivo in the mouse embryo" is on bioRxiv: www.biorxiv.org/content/10.6... . Amazing collaboration by @shenzhichen1999.bsky.social, Vincent Loubiere (@impvienna.bsky.social,@viennabiocenter.bsky.social),... (1/2)
Reposted by Eva Hörmanseder
Our new preprint is out: www.biorxiv.org/content/10.6...
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs.
A reminder of why bias-aware evaluation matters!
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs.
A reminder of why bias-aware evaluation matters!
Hidden sampling biases inflate performance in gene regulatory network inference
Accurate reconstruction of gene regulatory networks (GRNs) from single-cell transcriptomic data remains a major methodological challenge. Recent machine learning approaches, particularly graph neural ...
www.biorxiv.org
December 23, 2025 at 7:55 PM
Our new preprint is out: www.biorxiv.org/content/10.6...
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs.
A reminder of why bias-aware evaluation matters!
We show that GRN benchmarks commonly used can overestimate performance due to negative-sampling choices, sometimes allowing simple degree-based baselines to rival more complex GNNs.
A reminder of why bias-aware evaluation matters!
Reposted by Eva Hörmanseder
After a long journey, I'm happy to share that my PhD work is finally published in Nature Communications. Grateful to all my co-authors!
We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it:
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
nature.com
December 22, 2025 at 4:01 PM
After a long journey, I'm happy to share that my PhD work is finally published in Nature Communications. Grateful to all my co-authors!
We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it:
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
nature.com
December 22, 2025 at 2:38 PM
We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it:
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7
Reposted by Eva Hörmanseder
Do you want to play a key role in running a cutting-edge stem cell and embryology lab at reNEW @ucph.bsky.social ? We’re hiring a Lab Manager to support our team and help with stem cell and animal work. Apply before Feb. 1st : rb.gy/d5uf17
Academic employee for Research Group, Dept. of Biomedical Sciences, reNEW
rb.gy
December 17, 2025 at 12:53 PM
Do you want to play a key role in running a cutting-edge stem cell and embryology lab at reNEW @ucph.bsky.social ? We’re hiring a Lab Manager to support our team and help with stem cell and animal work. Apply before Feb. 1st : rb.gy/d5uf17
Reposted by Eva Hörmanseder
I’m thrilled to share that our project, FATERNA, has been awarded an ERC Consolidator Grant! We’ll explore the mechanisms of pre-mRNA fate control. Huge thanks go to our awesome research team, colleagues, and the fantastic support from @impvienna.bsky.social & @viennabiocenter.bsky.social CP.
The results of the ERC Consolidator Grant call have been announced! 📣
349 researchers have been selected for funding. Congratulations to all! #ERCCogG!
👉 buff.ly/uu62uFV
#FrontierResearch #EUfunded #HorizonEurope
@scienceinnovation.ec.europa.eu
349 researchers have been selected for funding. Congratulations to all! #ERCCogG!
👉 buff.ly/uu62uFV
#FrontierResearch #EUfunded #HorizonEurope
@scienceinnovation.ec.europa.eu
December 10, 2025 at 6:45 PM
I’m thrilled to share that our project, FATERNA, has been awarded an ERC Consolidator Grant! We’ll explore the mechanisms of pre-mRNA fate control. Huge thanks go to our awesome research team, colleagues, and the fantastic support from @impvienna.bsky.social & @viennabiocenter.bsky.social CP.
Reposted by Eva Hörmanseder
Excited to announce that our peer-reviewed manuscript is online in the Development journal @dev-journal.bsky.social. The manuscript was much improved through the peer-review process, and I am grateful to the reviewers for their valuable feedback.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development
Pioneer transcription factors are crucial for regulating zygotic genome activation and cell differentiation during mouse pre-implantation development. However, how pioneer factors function collectivel...
journals.biologists.com
December 8, 2025 at 5:57 PM
Excited to announce that our peer-reviewed manuscript is online in the Development journal @dev-journal.bsky.social. The manuscript was much improved through the peer-review process, and I am grateful to the reviewers for their valuable feedback.
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
Reposted by Eva Hörmanseder
A close-up piece on the legacy of Sir John Gurdon - so happy to see this out at @natcomms.nature.com. Excellent editorial and community work by @ebardot.bsky.social & thank you, @evahoermanseder.bsky.social et al.!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon - Nature Communications
Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon
www.nature.com
December 8, 2025 at 1:38 PM
A close-up piece on the legacy of Sir John Gurdon - so happy to see this out at @natcomms.nature.com. Excellent editorial and community work by @ebardot.bsky.social & thank you, @evahoermanseder.bsky.social et al.!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Eva Hörmanseder
We have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists.
The piece is available open access in Nature Communications:
www.nature.com/articles/s41...
The piece is available open access in Nature Communications:
www.nature.com/articles/s41...
Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon - Nature Communications
Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon
www.nature.com
December 5, 2025 at 8:05 AM
We have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists.
The piece is available open access in Nature Communications:
www.nature.com/articles/s41...
The piece is available open access in Nature Communications:
www.nature.com/articles/s41...
We are honored to share our Perspective in Nature Communications, reflecting on the legacy of John B. Gurdon.
Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications
Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications
Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon
Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon
rdcu.be
December 4, 2025 at 12:47 PM
We are honored to share our Perspective in Nature Communications, reflecting on the legacy of John B. Gurdon.
Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications
Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications
Yearly Lab Luncheon at John’s place. 2017
October 7, 2025 at 2:52 PM
Yearly Lab Luncheon at John’s place. 2017
Reposted by Eva Hörmanseder
The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story.
www.nytimes.com/2025/04/11/s...
www.nytimes.com/2025/04/11/s...
She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her (Gift Article)
President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.
www.nytimes.com
April 11, 2025 at 5:55 PM
The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story.
www.nytimes.com/2025/04/11/s...
www.nytimes.com/2025/04/11/s...
Reposted by Eva Hörmanseder
#EpigeneticsPodcast with #HelmholtzMunich expert Dr. Eva Hörmanseder, @epihmgu.bsky.social!
🎧 Listen and learn about epigenetic memories & more:
👉 t1p.de/30q54
👉Check out her latest findings on this topic:
t1p.de/43yrw
@epigeneticspod.bsky.social
#Epigenetics #Podcast #Reprogramming #CellFate
🎧 Listen and learn about epigenetic memories & more:
👉 t1p.de/30q54
👉Check out her latest findings on this topic:
t1p.de/43yrw
@epigeneticspod.bsky.social
#Epigenetics #Podcast #Reprogramming #CellFate
In this episode of the Epigenetics Podcast, we talked with @evahoermanseder.bsky.social from @www.helmholtz-munich.de about her work on epigenetic mechanisms in cellular memory and gene regulation. #podcast #epigenetics
Listen here: activemotif.com/podcasts-eva...
Listen here: activemotif.com/podcasts-eva...
March 28, 2025 at 11:02 AM
#EpigeneticsPodcast with #HelmholtzMunich expert Dr. Eva Hörmanseder, @epihmgu.bsky.social!
🎧 Listen and learn about epigenetic memories & more:
👉 t1p.de/30q54
👉Check out her latest findings on this topic:
t1p.de/43yrw
@epigeneticspod.bsky.social
#Epigenetics #Podcast #Reprogramming #CellFate
🎧 Listen and learn about epigenetic memories & more:
👉 t1p.de/30q54
👉Check out her latest findings on this topic:
t1p.de/43yrw
@epigeneticspod.bsky.social
#Epigenetics #Podcast #Reprogramming #CellFate
Reposted by Eva Hörmanseder
In the most recent episode we talked with @evahoermanseder.bsky.social from @www.helmholtz-munich.de about her work on epigenetic mechanisms in cellular memory and gene regulation. #podcast #epigenetics
Listen here: activemotif.com/podcasts-eva...
Listen here: activemotif.com/podcasts-eva...
March 31, 2025 at 8:01 AM
In the most recent episode we talked with @evahoermanseder.bsky.social from @www.helmholtz-munich.de about her work on epigenetic mechanisms in cellular memory and gene regulation. #podcast #epigenetics
Listen here: activemotif.com/podcasts-eva...
Listen here: activemotif.com/podcasts-eva...
Reposted by Eva Hörmanseder
This is very disturbing.
Harvard PhD student Kseniia Petrova (Russian citizen) was arrested by ICE for transporting xenopus embryos into Boston from Paris. She has been detained in Louisiana since Feb. 16.
www.theguardian.com/us-news/2025...
Harvard PhD student Kseniia Petrova (Russian citizen) was arrested by ICE for transporting xenopus embryos into Boston from Paris. She has been detained in Louisiana since Feb. 16.
www.theguardian.com/us-news/2025...
Russian scientist working at Harvard detained by Ice at Boston airport
Kseniia Petrova was returning to the US from a trip to France when officials revoked her visa and detained her
www.theguardian.com
March 29, 2025 at 8:38 AM
This is very disturbing.
Harvard PhD student Kseniia Petrova (Russian citizen) was arrested by ICE for transporting xenopus embryos into Boston from Paris. She has been detained in Louisiana since Feb. 16.
www.theguardian.com/us-news/2025...
Harvard PhD student Kseniia Petrova (Russian citizen) was arrested by ICE for transporting xenopus embryos into Boston from Paris. She has been detained in Louisiana since Feb. 16.
www.theguardian.com/us-news/2025...
If I could do it all over again, I’d apply here for my postdoc- look at these fantastic opportunities! ⬇️
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
March 28, 2025 at 6:12 PM
If I could do it all over again, I’d apply here for my postdoc- look at these fantastic opportunities! ⬇️
Reposted by Eva Hörmanseder
Reprogramming efficiency varies across cell types in vivo and is modulated by somatic cell identity memory. Eliminating somatic cell transcriptional memory improves reprogramming success #nucleartransfer ow.ly/g1Au50VimTM
@www.helmholtz-munich.de @isscr.org
@www.helmholtz-munich.de @isscr.org
March 18, 2025 at 5:10 PM
Reprogramming efficiency varies across cell types in vivo and is modulated by somatic cell identity memory. Eliminating somatic cell transcriptional memory improves reprogramming success #nucleartransfer ow.ly/g1Au50VimTM
@www.helmholtz-munich.de @isscr.org
@www.helmholtz-munich.de @isscr.org
Reposted by Eva Hörmanseder
We’d like to thank our Editors and peer reviewers who made the #fastandfairpeerreview trial possible. Would you like to join our reviewer pool? Visit bit.ly/41N31tO for more details.
March 28, 2025 at 11:24 AM
We’d like to thank our Editors and peer reviewers who made the #fastandfairpeerreview trial possible. Would you like to join our reviewer pool? Visit bit.ly/41N31tO for more details.
Reposted by Eva Hörmanseder
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends. This sounds like Trump trying to please Putin rather than anything to do with US immigration.
www.independent.co.uk/news/world/a...
www.independent.co.uk/news/world/a...
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends
Kseniia Petrova has been in U.S. detention since mid-February after having her visa revoked, according to friends and independent Russian media
www.independent.co.uk
March 28, 2025 at 9:07 AM
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends. This sounds like Trump trying to please Putin rather than anything to do with US immigration.
www.independent.co.uk/news/world/a...
www.independent.co.uk/news/world/a...
Our key collaborator, genius scientist and wonderful person Kseniia is in a horrendous situation right now, see article below. Why? Trump.
Please share, please do not ignore, if you can, help.
www.independent.co.uk/news/world/a...
Please share, please do not ignore, if you can, help.
www.independent.co.uk/news/world/a...
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends
Kseniia Petrova has been in U.S. detention since mid-February after having her visa revoked, according to friends and independent Russian media
www.independent.co.uk
March 28, 2025 at 11:11 AM
Our key collaborator, genius scientist and wonderful person Kseniia is in a horrendous situation right now, see article below. Why? Trump.
Please share, please do not ignore, if you can, help.
www.independent.co.uk/news/world/a...
Please share, please do not ignore, if you can, help.
www.independent.co.uk/news/world/a...
Thank you very much for this possibility to contribute to this podcast! …but, as it said in my recommendation letter, “she has a tendency to talk fast” :)
Thanks to everyone who contributed to these discoveries discussed here 🙏 Especially to those I forgot to mention cause I was so nervous…
Thanks to everyone who contributed to these discoveries discussed here 🙏 Especially to those I forgot to mention cause I was so nervous…
March 28, 2025 at 10:58 AM
Thank you very much for this possibility to contribute to this podcast! …but, as it said in my recommendation letter, “she has a tendency to talk fast” :)
Thanks to everyone who contributed to these discoveries discussed here 🙏 Especially to those I forgot to mention cause I was so nervous…
Thanks to everyone who contributed to these discoveries discussed here 🙏 Especially to those I forgot to mention cause I was so nervous…
Reposted by Eva Hörmanseder
🚨NEW PAPER ALERT!
3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail
@hamperllab.bsky.social
@antonio-scialdone.bsky.social
@evahoermanseder.bsky.social
Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social
3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail
@hamperllab.bsky.social
@antonio-scialdone.bsky.social
@evahoermanseder.bsky.social
Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social
Cell Fate Changes – Transcriptional Memory in Reprogramming
Dr. Eva Hörmanseder, #HelmholtzMunich & team uncovered why some cells resist reprogramming – a key hurdle for regenerative medicine.
👉 t1p.de/43yrw
@epihmgu.bsky.social
#CellReprogramming #Epigenetics #StemCells #RegenerativeMedicine
Dr. Eva Hörmanseder, #HelmholtzMunich & team uncovered why some cells resist reprogramming – a key hurdle for regenerative medicine.
👉 t1p.de/43yrw
@epihmgu.bsky.social
#CellReprogramming #Epigenetics #StemCells #RegenerativeMedicine
March 14, 2025 at 4:31 PM
🚨NEW PAPER ALERT!
3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail
@hamperllab.bsky.social
@antonio-scialdone.bsky.social
@evahoermanseder.bsky.social
Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social
3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail
@hamperllab.bsky.social
@antonio-scialdone.bsky.social
@evahoermanseder.bsky.social
Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social