Eva Hörmanseder
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evahoermanseder.bsky.social
Eva Hörmanseder
@evahoermanseder.bsky.social
Science for work- Mom, Knitter 🧶 at home

Love for Development, Reprogramming, Epigenetics and of course our frog Xenopus 🐸
Pinned
Yearly Lab Luncheon at John’s place. 2017
Yearly Lab Luncheon at John’s place. 2017
October 7, 2025 at 2:52 PM
Reposted by Eva Hörmanseder
The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story.
www.nytimes.com/2025/04/11/s...
She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her (Gift Article)
President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.
www.nytimes.com
April 11, 2025 at 5:55 PM
Reposted by Eva Hörmanseder
#EpigeneticsPodcast with #HelmholtzMunich expert Dr. Eva Hörmanseder, @epihmgu.bsky.social!

🎧 Listen and learn about epigenetic memories & more:
👉 t1p.de/30q54

👉Check out her latest findings on this topic:
t1p.de/43yrw

@epigeneticspod.bsky.social
#Epigenetics #Podcast #Reprogramming #CellFate
In this episode of the Epigenetics Podcast, we talked with @evahoermanseder.bsky.social from @www.helmholtz-munich.de‬ about her work on epigenetic mechanisms in cellular memory and gene regulation. #podcast #epigenetics

Listen here: activemotif.com/podcasts-eva...
March 28, 2025 at 11:02 AM
Reposted by Eva Hörmanseder
In the most recent episode we talked with @evahoermanseder.bsky.social from @www.helmholtz-munich.de‬ about her work on epigenetic mechanisms in cellular memory and gene regulation. #podcast #epigenetics

Listen here: activemotif.com/podcasts-eva...
March 31, 2025 at 8:01 AM
Reposted by Eva Hörmanseder
This is very disturbing.
Harvard PhD student Kseniia Petrova (Russian citizen) was arrested by ICE for transporting xenopus embryos into Boston from Paris. She has been detained in Louisiana since Feb. 16.

www.theguardian.com/us-news/2025...
Russian scientist working at Harvard detained by Ice at Boston airport
Kseniia Petrova was returning to the US from a trip to France when officials revoked her visa and detained her
www.theguardian.com
March 29, 2025 at 8:38 AM
If I could do it all over again, I’d apply here for my postdoc- look at these fantastic opportunities! ⬇️
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
March 28, 2025 at 6:12 PM
Reposted by Eva Hörmanseder
Reprogramming efficiency varies across cell types in vivo and is modulated by somatic cell identity memory. Eliminating somatic cell transcriptional memory improves reprogramming success #nucleartransfer ow.ly/g1Au50VimTM

@www.helmholtz-munich.de @isscr.org
March 18, 2025 at 5:10 PM
Reposted by Eva Hörmanseder
We’d like to thank our Editors and peer reviewers who made the #fastandfairpeerreview trial possible. Would you like to join our reviewer pool? Visit bit.ly/41N31tO for more details.
March 28, 2025 at 11:24 AM
Reposted by Eva Hörmanseder
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends. This sounds like Trump trying to please Putin rather than anything to do with US immigration.
www.independent.co.uk/news/world/a...
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends
Kseniia Petrova has been in U.S. detention since mid-February after having her visa revoked, according to friends and independent Russian media
www.independent.co.uk
March 28, 2025 at 9:07 AM
Our key collaborator, genius scientist and wonderful person Kseniia is in a horrendous situation right now, see article below. Why? Trump.

Please share, please do not ignore, if you can, help.

www.independent.co.uk/news/world/a...
Harvard scientist opposed to Ukraine war faces deportation back to Russia: Friends
Kseniia Petrova has been in U.S. detention since mid-February after having her visa revoked, according to friends and independent Russian media
www.independent.co.uk
March 28, 2025 at 11:11 AM
Thank you very much for this possibility to contribute to this podcast! …but, as it said in my recommendation letter, “she has a tendency to talk fast” :)

Thanks to everyone who contributed to these discoveries discussed here 🙏 Especially to those I forgot to mention cause I was so nervous…
March 28, 2025 at 10:58 AM
Reposted by Eva Hörmanseder
🚨NEW PAPER ALERT!

3 of our teams at IES collaborated to understand why some cells reprogram effectively while others fail
@hamperllab.bsky.social
@antonio-scialdone.bsky.social
@evahoermanseder.bsky.social

Congrats to all the authors of this exceptional paper published @stemcellreports.bsky.social
Cell Fate Changes – Transcriptional Memory in Reprogramming

Dr. Eva Hörmanseder, #HelmholtzMunich & team uncovered why some cells resist reprogramming – a key hurdle for regenerative medicine.

👉 t1p.de/43yrw

@epihmgu.bsky.social
#CellReprogramming #Epigenetics #StemCells #RegenerativeMedicine
March 14, 2025 at 4:31 PM
Reposted by Eva Hörmanseder
🚨New preprint from @bonevlab.bsky.social 🚨: What are the key epigenetic mechanisms that drive species-specific gene regulation during primate neurogenesis - and how do they contribute to the evolution of the human neocortex?
Here’s what we discovered 👇
www.biorxiv.org/content/10.1...
3D Epigenome Evolution Underlies Divergent Gene Regulatory Programs in Primate Neural Development
The expansion of the neocortex is a hallmark of human evolution and is closely linked to neural stem cell biology. Yet, the epigenetic mechanisms driving divergent gene regulation during primate neuro...
www.biorxiv.org
March 13, 2025 at 9:59 AM
Reposted by Eva Hörmanseder
Very happy to share the preprint of my main PhD project in the @bonevlab.bsky.social! Huge thanks to @boyanbonev.bsky.social, all co-authors and members of the @bonevlab.bsky.social! This work wouldn’t have been possible without your contributions!
March 13, 2025 at 12:18 PM
Reposted by Eva Hörmanseder
The last chapter of my PhD is finally out! Huge thanks to my supervisor @genikhovich.bsky.social for supporting “at first glance, stupid ideas” — which turned into a nice paper! That was so much fun!
March 13, 2025 at 5:20 PM
Thank you Antonio for this great collaboration!
Why do some cells resist nuclear reprogramming? Using nuclear transfer, we tracked single-cell fate changes in vivo and uncovered cell-type-specific barriers to reprogramming. Suppressing the old identity boosts success!

www.cell.com/stem-cell-re...
March 14, 2025 at 8:14 AM
Reposted by Eva Hörmanseder
Cell Fate Changes – Transcriptional Memory in Reprogramming

Dr. Eva Hörmanseder, #HelmholtzMunich & team uncovered why some cells resist reprogramming – a key hurdle for regenerative medicine.

👉 t1p.de/43yrw

@epihmgu.bsky.social
#CellReprogramming #Epigenetics #StemCells #RegenerativeMedicine
March 13, 2025 at 4:31 PM
Do you work with reprogrammed cells? Then look at our new paper!

We asked: How well do reprogrammed cells differentiate into complete&functional tissues?

We found that
- some cell types form perfectly but others fail
- reducing levels of one specific TF of the previous lineage can fix problems⬇️
Differentiation success of reprogrammed cells is heterogeneous in vivo and modulated by somatic cell identity memory
This study investigates how reprogramming success in vivo varies across cell types, revealing that gene expression of the previous somatic cell identity hinders proper differentiation. By following si...
www.cell.com
March 14, 2025 at 8:11 AM
Reposted by Eva Hörmanseder
A preprint from the lab- Corrections in single cell migration path in vivo are controlled by pulses in polar Rac1 activation.
www.biorxiv.org/content/10.1...
Corrections in single cell migration path in vivo are controlled by pulses in polar Rac1 activation
Directed migration of single cells is central to a large number of processes in development and adult life. Corrections to the migration path of cells are often characterized by periodic loss of polar...
www.biorxiv.org
February 27, 2025 at 6:05 AM
Reposted by Eva Hörmanseder
We are hiring.🚨 The Tissue Gene Regulation Lab is looking for an experimental PhD student or PostDoc to join our efforts in devising new single cell methods and decoding gene regulation. 💻🔬🧫
Come join me and my lab in beautiful Copenhagen. 🇩🇰

PhD - lnkd.in/dtKz_gnA
PostDoc - lnkd.in/dBgn6AcK
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
February 26, 2025 at 10:37 AM
Reposted by Eva Hörmanseder
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
 
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).

www.embl.org/about/info/c...
DNA replication and genome maintenance: from basic biology to disease
www.embl.org
February 26, 2025 at 3:22 PM
Reposted by Eva Hörmanseder
🚀 PREPRINT ALERT!

🐸 Research led by our PI @evahoermanseder.bsky.social reveals H3K4 methylation as an epigenetic memory in Xenopus embryos, vital for zygotic genome activation & development.

👏 Congratulations @meghana-oak.bsky.social & rest of authors.

📑 👀 shorturl.at/6MIRn

🔎 #OpenPeerReview
February 25, 2025 at 10:07 AM
Reposted by Eva Hörmanseder
🎆Next #FragileNucleosome meeting is less than a week away! We are delighted to host @manucazottes.bsky.social, @robertadolling1.bsky.social & @leandrosboukas.bsky.social ! We will discuss evolution of XIST regulatory network, cancer epigenetics, and MDEMs!
🗓️ us06web.zoom.us/webinar/regi...
February 22, 2025 at 11:55 AM
Congratulations Marcel, Manuel and everyone involved!
Wonderful work on transcription replication conflicts, check out highlights below ⬇️
February 20, 2025 at 7:04 PM
Reposted by Eva Hörmanseder
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...

#TRC #r-loop #chromatin

More below 👇
Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery
Abstract. Progressing transcription and replication machineries profoundly impact their underlying chromatin template. Consequently, transcription-replicat
academic.oup.com
February 20, 2025 at 1:38 PM