@pdhsu.bsky.social
Genomes encode biological complexity, which is determined by combinations of DNA mutations across millions of bases
In new work @arcinstitute.org, we report the discovery and engineering of the first programmable DNA recombinases capable of megabase-scale human genome rearrangement
In new work @arcinstitute.org, we report the discovery and engineering of the first programmable DNA recombinases capable of megabase-scale human genome rearrangement
May 15, 2025 at 1:47 PM
Genomes encode biological complexity, which is determined by combinations of DNA mutations across millions of bases
In new work @arcinstitute.org, we report the discovery and engineering of the first programmable DNA recombinases capable of megabase-scale human genome rearrangement
In new work @arcinstitute.org, we report the discovery and engineering of the first programmable DNA recombinases capable of megabase-scale human genome rearrangement
Reposted
This was a fun one — new Endpoints Slack interview with @pdhsu.bsky.social :
endpts.com/endpoints-sl...
endpts.com/endpoints-sl...
The Endpoints Slack interview: Arc Institute's Patrick Hsu on investing, AI and new ways of research
An interview with Patrick Hsu, 31, Harvard PhD grad and CRISPR pioneer, who co-founded Arc Institute and helped develop Evo 2, a biology-focused AI model.
endpts.com
April 30, 2025 at 3:09 PM
This was a fun one — new Endpoints Slack interview with @pdhsu.bsky.social :
endpts.com/endpoints-sl...
endpts.com/endpoints-sl...
are there good CROs for cell line engineering and generation?
March 24, 2025 at 11:48 PM
are there good CROs for cell line engineering and generation?
Reposted
Today, we're launching the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements. arc-website-git-ben-virtual-cell-atlas-tool-arc-institute.vercel.app/news/news/ar...
Arc Virtual Cell Atlas launches, combining data from over 300 million cells | Arc Institute
Arc Institute today launched the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements, starting with data from over 300 million cells. The initial release of the A...
arc-website-git-ben-virtual-cell-atlas-tool-arc-institute.vercel.app
February 25, 2025 at 2:03 PM
Today, we're launching the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements. arc-website-git-ben-virtual-cell-atlas-tool-arc-institute.vercel.app/news/news/ar...
Reposted
At the @arcinstitute.org we are building AI models of cell state from the ground up, rethinking every step, from data generation to biologically relevant evaluation
Today we launch scBaseCamp, the largest public repository of single cell RNAseq data, uniformly processed from raw sequencing reads.
Today we launch scBaseCamp, the largest public repository of single cell RNAseq data, uniformly processed from raw sequencing reads.
February 25, 2025 at 2:35 PM
At the @arcinstitute.org we are building AI models of cell state from the ground up, rethinking every step, from data generation to biologically relevant evaluation
Today we launch scBaseCamp, the largest public repository of single cell RNAseq data, uniformly processed from raw sequencing reads.
Today we launch scBaseCamp, the largest public repository of single cell RNAseq data, uniformly processed from raw sequencing reads.
Reposted
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling
Building predictive models of the cell requires systematically mapping how perturbations reshape each cell's state, function, and behavior. Here, we present Tahoe-100M, a giga-scale single-cell atlas ...
www.biorxiv.org
February 25, 2025 at 1:25 PM
@thejohnnyyu.bsky.social, @therealnima.bsky.social, and I, are excited to tell you about Tahoe-100M! The largest publicly available single-cell dataset that measures the effect of 1200 genes on 50 cell line models. The Vevo team has outdone itself. #Tahoe100M www.biorxiv.org/content/10.1...
Reposted
Watch @thejohnnyyu.bsky.social @therealnima.bsky.social (@vevotherapeutics.bsky.social), @pdhsu.bsky.social , Dave Burke and I (@arcinstitute.org) talking about virtual cells, and how #Tahoe100M, now on. @arcinstitute.org's Virtual Cell Atlas, can change the game!
www.youtube.com/watch?v=ak_f...
www.youtube.com/watch?v=ak_f...
No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
YouTube video by No Priors: AI, Machine Learning, Tech, & Startups
www.youtube.com
February 25, 2025 at 1:39 PM
Watch @thejohnnyyu.bsky.social @therealnima.bsky.social (@vevotherapeutics.bsky.social), @pdhsu.bsky.social , Dave Burke and I (@arcinstitute.org) talking about virtual cells, and how #Tahoe100M, now on. @arcinstitute.org's Virtual Cell Atlas, can change the game!
www.youtube.com/watch?v=ak_f...
www.youtube.com/watch?v=ak_f...
Reposted
New from @arcinstitute.org is "the largest publicly available #AI model for biology to date"!
Evo 2 now includes information from all domains in life to expand its capabilities in generative functional genomics. @pdhsu.bsky.social @brianhie.bsky.social
tinyurl.com/3t83vseh
Evo 2 now includes information from all domains in life to expand its capabilities in generative functional genomics. @pdhsu.bsky.social @brianhie.bsky.social
tinyurl.com/3t83vseh
Arc Institute’s AI Model Evo 2 Designs the Genetic Code Across All Domains of Life
Evo 2 now includes information from humans, plants, and other eukaryotic species to expand its capabilities in generative functional genomics.
tinyurl.com
February 19, 2025 at 6:17 PM
New from @arcinstitute.org is "the largest publicly available #AI model for biology to date"!
Evo 2 now includes information from all domains in life to expand its capabilities in generative functional genomics. @pdhsu.bsky.social @brianhie.bsky.social
tinyurl.com/3t83vseh
Evo 2 now includes information from all domains in life to expand its capabilities in generative functional genomics. @pdhsu.bsky.social @brianhie.bsky.social
tinyurl.com/3t83vseh
AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
February 19, 2025 at 4:35 PM
AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.
Reposted
Introducing Evo 2 from Arc Institute - an AI that can model and design the genetic code for all domains of life. It’s one of the largest-scale truly open source AI models for biology (and in fact more generally - most “open source” large language models are only “open weights”)
February 19, 2025 at 4:05 PM
Introducing Evo 2 from Arc Institute - an AI that can model and design the genetic code for all domains of life. It’s one of the largest-scale truly open source AI models for biology (and in fact more generally - most “open source” large language models are only “open weights”)