PaquetLab
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paquetlab.bsky.social
PaquetLab
@paquetlab.bsky.social
3D iPSC models and CRISPR to investigate mechanisms of neurodegenerative and neurovascular disorders | Professor of Neurobiology at LMU Munich | https://isd-research.de/paquetlab
Big congrats to Mila @milaborri.bsky.social from the lab for obtaining a EU-funded #MCSA postdoc fellowship!! We look forward to working with you on developing #iPSC based vascularized human brain tissue models to study major #brain diseases, such as #Alzheimer's and #stroke!
October 9, 2025 at 6:58 AM
Very happy to be at the Barcelona #B4event blood-brain-barrier meeting and present our work this afternoon on a novel fully #iPSC based model of the #BBB that allows investigating neurovascular diseases! premc.org/blood-brain-...
October 1, 2025 at 1:50 PM
Great to be at #Tau2025 in London, where @angelikadannert.bsky.social from the lab presents our human #iPSC model of Tauopathies in a packed poster session
April 24, 2025 at 3:11 PM
If you are at #ADPD2025 in Vienna, please join us now in hall F1 to get an update about our human 3D #iPSC model of #Alzheimer disease!
April 2, 2025 at 2:36 PM
Great talks and discussions at the 🧠 #SCMND meeting in Edinburgh this week, where @julien-klimmt.bsky.social from our lab presented our #ipsc 3D brain tissue model for #Alzheimer’s diseases to a full audience
March 29, 2025 at 6:59 AM
Open #Postdoc position @isd-research.bsky.social @lmumuenchen.bsky.social to develop an #iPSC-derived #BBB model. Fully funded and embedded in our international Foundation Leducq Network of Excellence www.brenda-leducq.de Experience in vascular biology or related field required. Please RP and apply
March 12, 2025 at 4:42 PM
Lastly, we concluded an exciting year with our annual Christmas party - many thanks to all lab members for a great year 2024!
January 13, 2025 at 9:04 AM
In October, lab members presented our work at the 4th Project Meeting of our BRENDA #Leducq Foundation network in Burlington, USA, hosted by Mark Nelson’s group www.brenda-leducq.de/brenda#news
January 13, 2025 at 9:04 AM
In September, we kicked off our #JPND collaboration on #PLCG2 at a meeting in the nice town of #Lille.
January 13, 2025 at 9:04 AM
In August, we celebrated Angelika's #PhD at the #GSN graduation day ceremony.
January 13, 2025 at 9:04 AM
In July, we co-organized our institute's annual scientific retreat, with presentations and posters from lab and institute's members, and an exciting talk from our fantastic guest speaker Moritz Helmstaedter from #MPI for Brain Research for a really inspiring talk about #connectomics!
January 13, 2025 at 9:04 AM
In May, Dominik discussed our work on #iPSC models for investigating mechanisms of brain diseases in an invited talk at Vall d'Hebron Institut de Recerca, and presented our fully #iPSC derived model of the #bloodbrainbarrier in a talk at the #EMBOBuildNetworks meeting, both in #Barcelona.
January 13, 2025 at 9:04 AM
In April, Angelika Dannert, #GSN graduate student from the lab working on a #iPSC model of #Tauopathies, graduated with flying colors. Big congrats Angelika (and thanks lab for the nice hat!)
January 13, 2025 at 9:04 AM
Furthermore, members of the lab presented at the #StemCellTuebingen conference and Carolina won an award for the best poster!
January 13, 2025 at 9:04 AM
In March, Dominik chaired a session on 'Vascular Diseases: Mechanisms, Pathophysiology' at #ADPD and presented our new fully #iPSC derived model of the blood-brain-barrier to investigate neurovascular diseases.
January 13, 2025 at 9:04 AM
... molecular mechanisms of #neurodegeneration and #neurovascular diseases, including #Alzheimer's, #Frontotemporal-dementia, #stroke and small vessels disease (#SVD). We apply cutting-edge technology including #iPSCs, #CRISPR genome editing and human #tissue engineering. Follow us to hear more!
January 12, 2025 at 3:15 PM