With so many new methods buried in results-focused papers, this thread is my encouragement to groups to also publish separate protocols papers! You'll be pleasantly surprised at the engagement these papers get, and most importantly they provide real impact aiding others in their science.

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

I’m excited to share our lab’s new preprint! We find that some exhausted T cell clones maintain the capacity form functional memory cells:
www.biorxiv.org/content/10.1...

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Cool stuff from my friends!

Excited to announce that my research focusing on discovering anti-metastatic immunotherapies and regulators of secondary metastasis will be funded by the Early Career Investigator Award from
@metavivor.bsky.social! Thank you for the support! www.metavivor.org/blog/metaviv...

Congratulations to the @caleblareau.bsky.social lab for being awarded a prestigious grant under the NIH Common Fund Human Virome Program 👏👏

You can learn more about the lab's work below and get a glimpse into the project our #MSKPostdoc Erin Cumming is working on.

New preprint documenting a common but oft-under-appreciated source of noise, which is ignored at one's peril: "These findings reveal extensive barcode swapping during AAV pooled packaging that significantly compromises cell type specificity measurements from barcoded enhancer AAVs."

Native IL-9/IL-9R as a natural cytokine-receptor pair with near-orthogonal qualities and an optimal JAK/STAT signaling profile for engineered T cell therapy
doi.org/10.1101/2025...
@xrtcell.bsky.social

Ansuman Satpathy will engineer T cell states with enhanced anti-cancer activity using synthetic transcription factors to modulate gene expression and advanced machine learning tools.