@new299.bsky.social
The Roche SBX e-book available for free subscribers of the substack seems to be doing well. Considering books on Illumina, PacBio! Availavle when you subscribe at aseq.substack.com/subscribe
Subscribe to ASeq Newsletter
A Sequencing technology newsletter. Click to read ASeq Newsletter, by Nava Whiteford, a Substack publication.
aseq.substack.com
May 6, 2025 at 12:49 AM
The Roche SBX e-book available for free subscribers of the substack seems to be doing well. Considering books on Illumina, PacBio! Availavle when you subscribe at aseq.substack.com/subscribe
Wrote a short ebook on Roche’s SBX Nanopore sequencing approach. Available to free subscribers here: aseq.substack.com/subscribe
Subscribe to ASeq Newsletter
A Sequencing technology newsletter. Click to read ASeq Newsletter, by Nava Whiteford, a Substack publication.
aseq.substack.com
May 5, 2025 at 1:38 PM
Wrote a short ebook on Roche’s SBX Nanopore sequencing approach. Available to free subscribers here: aseq.substack.com/subscribe
Reposted
Happy Monday! Let's start this week with fairy tales!
ONCE UPON A TIME extracting high molecular weight (HMW) DNA was difficult. But now, with @pacbio.bsky.social Nanobind extraction kits. you get HMW DNA in, and beautiful long reads -> genome assemblies out! 💫⭐🧪🧬
www.pacb.com/products-and...
ONCE UPON A TIME extracting high molecular weight (HMW) DNA was difficult. But now, with @pacbio.bsky.social Nanobind extraction kits. you get HMW DNA in, and beautiful long reads -> genome assemblies out! 💫⭐🧪🧬
www.pacb.com/products-and...
March 3, 2025 at 5:50 PM
Happy Monday! Let's start this week with fairy tales!
ONCE UPON A TIME extracting high molecular weight (HMW) DNA was difficult. But now, with @pacbio.bsky.social Nanobind extraction kits. you get HMW DNA in, and beautiful long reads -> genome assemblies out! 💫⭐🧪🧬
www.pacb.com/products-and...
ONCE UPON A TIME extracting high molecular weight (HMW) DNA was difficult. But now, with @pacbio.bsky.social Nanobind extraction kits. you get HMW DNA in, and beautiful long reads -> genome assemblies out! 💫⭐🧪🧬
www.pacb.com/products-and...
Reposted
All The DNA Sequencing Companies
open.substack.com/pub/aseq/p/a...
open.substack.com/pub/aseq/p/a...
All The DNA Sequencing Companies
Shawn has a really good list of current (and dead) DNA sequencing companies. I also had a list which I stopped updating in 2020.
open.substack.com
February 17, 2025 at 10:14 AM
All The DNA Sequencing Companies
open.substack.com/pub/aseq/p/a...
open.substack.com/pub/aseq/p/a...
I then fully documented the Chromium pneumatic system, this was also fun!
aseq.substack.com/p/the-10x-ch...
aseq.substack.com/p/the-10x-ch...
The 10X Chromium Controller Pneumatic System
Last time I looked at the Chromium Controller estimating its BOM cost at <$5000. This time I wanted to further document the pneumatic system which forms the core of the Chromium Controller. You can se...
aseq.substack.com
January 26, 2025 at 5:47 AM
I then fully documented the Chromium pneumatic system, this was also fun!
aseq.substack.com/p/the-10x-ch...
aseq.substack.com/p/the-10x-ch...
About a year ago I pulled apart a 10X Chromium and estimated the component cost, that was fun!
aseq.substack.com/p/10x-chromi...
aseq.substack.com/p/10x-chromi...
10X Chromium Controller Component Cost Is Likely <$5000
There’s been recent talk of instrument-less single cell analysis platforms. One of the potential advantages here is you no longer need to buy an instrument (like the 10X Chromium controller) to perfor...
aseq.substack.com
January 26, 2025 at 5:45 AM
About a year ago I pulled apart a 10X Chromium and estimated the component cost, that was fun!
aseq.substack.com/p/10x-chromi...
aseq.substack.com/p/10x-chromi...
Reposted
H/t to Nava for spotting this & posting to ASeq discord
First question posted to @nanopore CEO Gordon Sanghera at #JPM25 had 2 parts:
1. Do they have long read technology?
2. Do they see value in long reads?
First question posted to @nanopore CEO Gordon Sanghera at #JPM25 had 2 parts:
1. Do they have long read technology?
2. Do they see value in long reads?
January 14, 2025 at 6:21 PM
H/t to Nava for spotting this & posting to ASeq discord
First question posted to @nanopore CEO Gordon Sanghera at #JPM25 had 2 parts:
1. Do they have long read technology?
2. Do they see value in long reads?
First question posted to @nanopore CEO Gordon Sanghera at #JPM25 had 2 parts:
1. Do they have long read technology?
2. Do they see value in long reads?
4 years ago I wrote an article on the next few years in DNA sequencing. Planning to review on the substack next week: 41j.com/blog/2021/05...
The Next Few Years in DNA Sequencing
Some was asking on Twitter about the effect of Illumina’s IP expiring on the sequencing industry. I figured I’d summarize my thoughts here. I’m not a patent lawyer, so you should consider tha…
41j.com
January 24, 2025 at 6:18 PM
4 years ago I wrote an article on the next few years in DNA sequencing. Planning to review on the substack next week: 41j.com/blog/2021/05...
The long… long… history for Roche’s nanopore DNA sequencing approach!
aseq.substack.com/p/a-roche-na...
aseq.substack.com/p/a-roche-na...
A Roche Nanopore History
Executive Summary: There’s a long rich history of nanopore sequencing, and Roche-style Xpandomer sequencing.
aseq.substack.com
January 24, 2025 at 11:57 AM
The long… long… history for Roche’s nanopore DNA sequencing approach!
aseq.substack.com/p/a-roche-na...
aseq.substack.com/p/a-roche-na...
Reposted
There is so much speculation about this. According to Aseq, it is expected to be a big box generating 15B reads in 4hrs, most likely at Q20 with 500 bp reads. What is worth noting is that Roche is not a startup, they have the resources to see this through. aseq.substack.com/p/roche-nano...
January 23, 2025 at 2:19 PM
There is so much speculation about this. According to Aseq, it is expected to be a big box generating 15B reads in 4hrs, most likely at Q20 with 500 bp reads. What is worth noting is that Roche is not a startup, they have the resources to see this through. aseq.substack.com/p/roche-nano...
