Julian Gargiulo
@nano-juli.bsky.social
Physicist and dad. Developing photonics tools for plasmonic chemistry and nanothermometry at UNSAM.
Drosophila brain imaging by #SnoutClub.
Photons are my own.
Drosophila brain imaging by #SnoutClub.
Photons are my own.
Reposted by Julian Gargiulo
📢Check out our latest #preprint list on FocalPlane
This list focusses on the latest research on bioimage analysis and data management. Let us know if there are any preprints that we should add to our list and send us recommendation for the next one!
focalplane.biologists.com/2025/11/14/m...
This list focusses on the latest research on bioimage analysis and data management. Let us know if there are any preprints that we should add to our list and send us recommendation for the next one!
focalplane.biologists.com/2025/11/14/m...
Microscopy preprints – bioimage analysis - FocalPlane
Microscopy preprints – bioimage analysis - News
focalplane.biologists.com
November 18, 2025 at 10:07 AM
📢Check out our latest #preprint list on FocalPlane
This list focusses on the latest research on bioimage analysis and data management. Let us know if there are any preprints that we should add to our list and send us recommendation for the next one!
focalplane.biologists.com/2025/11/14/m...
This list focusses on the latest research on bioimage analysis and data management. Let us know if there are any preprints that we should add to our list and send us recommendation for the next one!
focalplane.biologists.com/2025/11/14/m...
So happy to work with this great team.
Please check out our latest article.
Please check out our latest article.
SO HAPPY to share our new paper in @currentbiology.bsky.social! Using volumetric EM, we found daily shifts in synapses, vesicles, and mitochondria that accompany neuronal remodeling, linking structural plasticity to changes in how s-LNv neurons influence their targets
www.cell.com/current-biol...
www.cell.com/current-biol...
Daily ultrastructural remodeling of clock neurons
A cluster of Drosophila clock neurons remodel their axonal arbors daily. Using volumetric
electron microscopy at different times of day, Ispizua, Rodriguez-Caron, and colleagues
reveal ultrastructural...
www.cell.com
November 20, 2025 at 12:55 AM
So happy to work with this great team.
Please check out our latest article.
Please check out our latest article.
This is great news for Argentina!
Luciano is one of the most talented and successful researchers I've ever met, and Argentina's optics community is lucky to have him back!
Bienvenido!!!
Luciano is one of the most talented and successful researchers I've ever met, and Argentina's optics community is lucky to have him back!
Bienvenido!!!
Thrilled to announce some big news!
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
Excited to share that I’ve been awarded a Wellcome Trust Early Career Award to establish my research as a Group Leader in the Glycosciences Program at the Institute of Biology and Experimental Medicine (IBYME) in Buenos Aires, Argentina, beginning in early 2026.
October 19, 2025 at 1:03 AM
This is great news for Argentina!
Luciano is one of the most talented and successful researchers I've ever met, and Argentina's optics community is lucky to have him back!
Bienvenido!!!
Luciano is one of the most talented and successful researchers I've ever met, and Argentina's optics community is lucky to have him back!
Bienvenido!!!
We are seeking assistance in locating a missing researcher in Germany. If anyone is based in Germany or has contacts in the area who might be able to help, please get in touch as soon as possible.
Any information or support you can provide would be greatly appreciated.
Any information or support you can provide would be greatly appreciated.
October 16, 2025 at 12:10 AM
We are seeking assistance in locating a missing researcher in Germany. If anyone is based in Germany or has contacts in the area who might be able to help, please get in touch as soon as possible.
Any information or support you can provide would be greatly appreciated.
Any information or support you can provide would be greatly appreciated.
Reposted by Julian Gargiulo
Extremely excited to share quite an achievement for our group. Two years ago, we started #PhasorPy (www.phasorpy.org, now in our v0.8). In parallel, Bruno Pannunzio, in collaboration with Marcelo Zoccoller, led the hashtag#Napari_Phasors plugin v0.1 for FLIM & HSI phasor analysis.
October 15, 2025 at 3:16 PM
Extremely excited to share quite an achievement for our group. Two years ago, we started #PhasorPy (www.phasorpy.org, now in our v0.8). In parallel, Bruno Pannunzio, in collaboration with Marcelo Zoccoller, led the hashtag#Napari_Phasors plugin v0.1 for FLIM & HSI phasor analysis.
Reposted by Julian Gargiulo
This is insane. 13 years ago we bought a million dollar #microscope to do this type of super-resolution imaging. Today, all you need is a smartphone and a few hundred bucks of off-the-shelf components 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope - Nature Communications
Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely distributed applications in diagnostics, biosensing, and science education.
www.nature.com
October 9, 2025 at 6:36 PM
This is insane. 13 years ago we bought a million dollar #microscope to do this type of super-resolution imaging. Today, all you need is a smartphone and a few hundred bucks of off-the-shelf components 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julian Gargiulo
Playing around with how to represent volume in #Snouty light sheet data. Here is a dividing hiPSC with endogenously tagged histone in all three orthogonal projections. Bluer is further away. If anything, it distracts from politics.
October 8, 2025 at 7:57 PM
Playing around with how to represent volume in #Snouty light sheet data. Here is a dividing hiPSC with endogenously tagged histone in all three orthogonal projections. Bluer is further away. If anything, it distracts from politics.
Reposted by Julian Gargiulo
Happy to share this article with my views on @elislenders.bsky.social and @vicidominilab.bsky.social work and discussing current developments in single-molecule localization combining structured excitation and detection. So many exciting perspectives in the field!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Localization of single molecules with structured illumination and structured detection - Light: Science & Applications
Light: Science & Applications - Localization of single molecules with structured illumination and structured detection
www.nature.com
September 30, 2025 at 6:17 PM
Happy to share this article with my views on @elislenders.bsky.social and @vicidominilab.bsky.social work and discussing current developments in single-molecule localization combining structured excitation and detection. So many exciting perspectives in the field!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julian Gargiulo
Here's a six-month time-lapse of me building the single objective light sheet fluorescence microscope at the UCSF Center for Advanced Light Microscopy!
Also pictured is @nicostuurman.bsky.social and @kahsage.bsky.social.
#snouty
Also pictured is @nicostuurman.bsky.social and @kahsage.bsky.social.
#snouty
August 20, 2025 at 6:57 PM
Here's a six-month time-lapse of me building the single objective light sheet fluorescence microscope at the UCSF Center for Advanced Light Microscopy!
Also pictured is @nicostuurman.bsky.social and @kahsage.bsky.social.
#snouty
Also pictured is @nicostuurman.bsky.social and @kahsage.bsky.social.
#snouty
Reposted by Julian Gargiulo
“A #SPADarray in any laser scanning #microscope”. That is the latest effort from a group of people that shared this mantra. Proud of all of them.
@erc.europa.eu
#imagescanningmicroscopy #photonresolvedmicroscopy
#superresolution
#BrightEyes_ERC
doi.org/10.1038/s415...
@erc.europa.eu
#imagescanningmicroscopy #photonresolvedmicroscopy
#superresolution
#BrightEyes_ERC
doi.org/10.1038/s415...
July 24, 2025 at 12:11 PM
“A #SPADarray in any laser scanning #microscope”. That is the latest effort from a group of people that shared this mantra. Proud of all of them.
@erc.europa.eu
#imagescanningmicroscopy #photonresolvedmicroscopy
#superresolution
#BrightEyes_ERC
doi.org/10.1038/s415...
@erc.europa.eu
#imagescanningmicroscopy #photonresolvedmicroscopy
#superresolution
#BrightEyes_ERC
doi.org/10.1038/s415...
Reposted by Julian Gargiulo
Happy Pi day to those who like to arrange units by order of magnitude.
July 22, 2025 at 7:45 PM
Happy Pi day to those who like to arrange units by order of magnitude.
Reposted by Julian Gargiulo
Un submarino español usa una pila de hidrógeno basada en un proceso que desarrolló Miguel Laborde.
Acá lo cuenta con @aleberco en @pasaroncosas899
El problema no es el sistema de ciencia y tecnología sino el modelo de desarrollo.
radiocut.fm/audiocut/ent...
Acá lo cuenta con @aleberco en @pasaroncosas899
El problema no es el sistema de ciencia y tecnología sino el modelo de desarrollo.
radiocut.fm/audiocut/ent...
Entrevista Miguel Laborde, tecnólogo argentino
Miguel Laborde cuenta la situación actual del sistema de ciencia y técnica y su participación en el desarrollo de una pila que usa un submarino español.
radiocut.fm
June 27, 2025 at 8:23 PM
Un submarino español usa una pila de hidrógeno basada en un proceso que desarrolló Miguel Laborde.
Acá lo cuenta con @aleberco en @pasaroncosas899
El problema no es el sistema de ciencia y tecnología sino el modelo de desarrollo.
radiocut.fm/audiocut/ent...
Acá lo cuenta con @aleberco en @pasaroncosas899
El problema no es el sistema de ciencia y tecnología sino el modelo de desarrollo.
radiocut.fm/audiocut/ent...
Lasers on at UNSAM.
June 11, 2025 at 9:43 PM
Lasers on at UNSAM.
Reposted by Julian Gargiulo
Thrilled to share that my first #micropublication is out! 🧬🔬 I created a user-friendly ImageJ/FIJI plugin for nuclear segmentation and multi-channel fluorescence analysis that doesn't require programming skills.
www.micropublication.org/journals/bio...
www.micropublication.org/journals/bio...
Multi-Channel Nuclear Analysis: An ImageJ/FIJI Plugin for Automated Nuclear Segmentation and Multi-Channel Fluorescence Analysis | microPublication
www.micropublication.org
June 7, 2025 at 2:41 PM
Thrilled to share that my first #micropublication is out! 🧬🔬 I created a user-friendly ImageJ/FIJI plugin for nuclear segmentation and multi-channel fluorescence analysis that doesn't require programming skills.
www.micropublication.org/journals/bio...
www.micropublication.org/journals/bio...
Milei government is destroying the Argentine scientific system.
We resist
www.nature.com/articles/d41...
We resist
www.nature.com/articles/d41...
‘Scienticide’ in Argentina sparks huge protest by researchers
Hundreds of activists wearing gas masks took to the streets to call out their government for slashing science funding.
www.nature.com
May 30, 2025 at 11:35 AM
Milei government is destroying the Argentine scientific system.
We resist
www.nature.com/articles/d41...
We resist
www.nature.com/articles/d41...
Reposted by Julian Gargiulo
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
www.nature.com
May 7, 2025 at 2:56 PM
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
May 7, 2025 at 10:55 PM
Reposted by Julian Gargiulo
Read preprints. Cite preprints. Email people and tell them you loved their preprint. Email people you hated their preprint. Embrace preprints, preprints are good.
April 22, 2025 at 7:11 PM
Read preprints. Cite preprints. Email people and tell them you loved their preprint. Email people you hated their preprint. Embrace preprints, preprints are good.
Reposted by Julian Gargiulo
Our manuscript on accelerating the acquisition rate in oblique plane microscopy (OPM) is online now:
opg.optica.org/boe/fulltext...
Our work addresses the issue that an OPM PSF is tilted, and as such it leaves a lot of "empty space" in Fourier space (FFT of experimental data on the right)... 1/n
opg.optica.org/boe/fulltext...
Our work addresses the issue that an OPM PSF is tilted, and as such it leaves a lot of "empty space" in Fourier space (FFT of experimental data on the right)... 1/n
April 2, 2025 at 6:21 PM
Our manuscript on accelerating the acquisition rate in oblique plane microscopy (OPM) is online now:
opg.optica.org/boe/fulltext...
Our work addresses the issue that an OPM PSF is tilted, and as such it leaves a lot of "empty space" in Fourier space (FFT of experimental data on the right)... 1/n
opg.optica.org/boe/fulltext...
Our work addresses the issue that an OPM PSF is tilted, and as such it leaves a lot of "empty space" in Fourier space (FFT of experimental data on the right)... 1/n
Reposted by Julian Gargiulo
Another nice example from the 1st Snouty light-sheet microscope!
-> Here we show a mammalian cell with 2 fluorescent reporters imaged at ~1 volume per second. The speed and gentleness of the microscope make it ideal for 3D tracking and segmentation!
Prepared and imaged by @jlazzaridean.bsky.social
-> Here we show a mammalian cell with 2 fluorescent reporters imaged at ~1 volume per second. The speed and gentleness of the microscope make it ideal for 3D tracking and segmentation!
Prepared and imaged by @jlazzaridean.bsky.social
April 1, 2025 at 3:56 PM
Another nice example from the 1st Snouty light-sheet microscope!
-> Here we show a mammalian cell with 2 fluorescent reporters imaged at ~1 volume per second. The speed and gentleness of the microscope make it ideal for 3D tracking and segmentation!
Prepared and imaged by @jlazzaridean.bsky.social
-> Here we show a mammalian cell with 2 fluorescent reporters imaged at ~1 volume per second. The speed and gentleness of the microscope make it ideal for 3D tracking and segmentation!
Prepared and imaged by @jlazzaridean.bsky.social
Hi #SnoutClub and microscopy people.
Can you suggest python software for 3D registration?
I want to find the axial shift between two z-stacks
Thanks!!
Can you suggest python software for 3D registration?
I want to find the axial shift between two z-stacks
Thanks!!
April 1, 2025 at 2:07 PM
Hi #SnoutClub and microscopy people.
Can you suggest python software for 3D registration?
I want to find the axial shift between two z-stacks
Thanks!!
Can you suggest python software for 3D registration?
I want to find the axial shift between two z-stacks
Thanks!!
Reposted by Julian Gargiulo
HILO: Hace instantes se publicó nuestro nuevo trabajo del LANSAB-UNAHUR por Magalí di Meglio, Daniela Maza Vega y yo. Es un editorial sobre las chances reales y desafíos de la nanotecnología para tratar la leishmaniasis: www.tandfonline.com/doi/full/10....
1/4
1/4
How could the translation of nanotechnology-based therapies revolutionize cutaneous leishmaniasis treatments?
Published in Nanomedicine (Ahead of Print, 2025)
www.tandfonline.com
March 26, 2025 at 6:28 PM
HILO: Hace instantes se publicó nuestro nuevo trabajo del LANSAB-UNAHUR por Magalí di Meglio, Daniela Maza Vega y yo. Es un editorial sobre las chances reales y desafíos de la nanotecnología para tratar la leishmaniasis: www.tandfonline.com/doi/full/10....
1/4
1/4
📣SEMINARIO INS
El investigador Alberto Scarpettini charlará sobre nanoestructuras híbridas núcleo-satélite formadas por satélites plasmónicos de oro soportados sobre núcleos magnéticos de óxidos de hierro para la remediación asistida por luz solar de agua que contiene arsénico
El investigador Alberto Scarpettini charlará sobre nanoestructuras híbridas núcleo-satélite formadas por satélites plasmónicos de oro soportados sobre núcleos magnéticos de óxidos de hierro para la remediación asistida por luz solar de agua que contiene arsénico
March 19, 2025 at 6:10 PM
📣SEMINARIO INS
El investigador Alberto Scarpettini charlará sobre nanoestructuras híbridas núcleo-satélite formadas por satélites plasmónicos de oro soportados sobre núcleos magnéticos de óxidos de hierro para la remediación asistida por luz solar de agua que contiene arsénico
El investigador Alberto Scarpettini charlará sobre nanoestructuras híbridas núcleo-satélite formadas por satélites plasmónicos de oro soportados sobre núcleos magnéticos de óxidos de hierro para la remediación asistida por luz solar de agua que contiene arsénico
Reposted by Julian Gargiulo
Con @marieldemente.bsky.social y @agmendez.bsky.social grabamos un nuevo episodio de Ocultonas, sobre posesiones, exorcismos y discernimiento de espíritus. No se lo pierdan que quedó geniallll
open.spotify.com/episode/5dte...
open.spotify.com/episode/5dte...
Posesiones
Ocultonas · Episode
open.spotify.com
March 3, 2025 at 6:52 PM
Con @marieldemente.bsky.social y @agmendez.bsky.social grabamos un nuevo episodio de Ocultonas, sobre posesiones, exorcismos y discernimiento de espíritus. No se lo pierdan que quedó geniallll
open.spotify.com/episode/5dte...
open.spotify.com/episode/5dte...