Nanion Technologies
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naniontech.bsky.social
Nanion Technologies
@naniontech.bsky.social
For 20+ years, Nanion combines exceptional instrumentation with trusted scientific support, to accelerate successful drug development and scientific discoveries.
Reduce variability in NaV studies with adaptive voltage clamp on the SyncroPatch 384.

Tailor Vhalf per well, gain better IC50 precision, and study state-dependent effects with confidence.

Check out the flyer to see how it works!
ow.ly/8QMU50WFXei

#APC #IonChannels #NaV #Electrophysiology
August 14, 2025 at 12:45 PM
How do CaV1.2 mutations drive both arrhythmias and neuro symptoms in Timothy syndrome?

Join Ivy Dick on June 12 to learn how high-throughput patch clamp reveals mutation-specific gating changes tied to clinical outcomes.

📍https://ow.ly/PxZY50W72H7

#PatchClamp #Channelopathies #IonChannels
June 10, 2025 at 2:29 PM
Most cardiac gene variants are still classed as “uncertain.”

Join us on Thursday to learn how APC is helping reclassify VUS and improve clinical decisions.

🗓️ May 8 | 16:00–17:00 CEST
🔗 ow.ly/RQfB50VFl93

Hope to see you there!
#CardiacGenetics #APC #VUS #LQTS #Brugada
May 5, 2025 at 3:08 PM
How do beta-lactam antibiotics get into our cells, and how can we use that to design better drugs?

Join our webinar on May 14 to explore new insights into PepT2, drug uptake, and delivery.

🔗 Register: ow.ly/1mCL50Vo2j8

#PepT2 #DrugDesign #CryoEM #Webinar
April 28, 2025 at 12:34 PM
Why is NHE9 active in endosomes but silent at the membrane?

A new Nature Communications study reveals a lipid switch: PI(3,5)P₂ stabilizes NHE9’s dimer only in endosomes.

🔗Read the full article to find out more: ow.ly/zrsR50VAAZW

#MembraneTransport #CryoEM #SSME
April 15, 2025 at 4:46 PM
𝗖𝗮𝗻 𝘄𝗲 𝗶𝗺𝗽𝗿𝗼𝘃𝗲 𝘁𝗵𝗲 𝘄𝗮𝘆 𝘄𝗲 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁 𝗰𝗮𝗿𝗱𝗶𝗮𝗰 𝗴𝗲𝗻𝗲 𝘃𝗮𝗿𝗶𝗮𝗻𝘁𝘀?

Join Dr. Chai Ng (Victor Chang Cardiac Research Institute) on May 8 to explore APC’s role in variant classification for inherited arrhythmias.

🔗 ow.ly/XrnO50VymFI

#Webinar @chaiannng.bsky.social @victorchang.edu.au
April 11, 2025 at 10:19 AM
iPSC-CMs are powerful, but their immaturity limits their predictive value. A recent study from TU Dresden shows how combining metabolic medium, nanopatterning, and electrostimulation significantly enhances structural and electrophysiological maturation.

🔗 lnkd.in/dipXpmyN

#Cardiac #iPSC #APC
April 10, 2025 at 3:03 PM
TRPV3 is a temperature-sensitive, ligand-gated ion channel known for its role in warmth perception.

It can be activated by heat (~ 38˚C) or by 2-APB, and we have explored both activation modes using APC with temp control.

Read the app note: ow.ly/YMp850R6hwG
#TRPV3 #IonChannels #Electrophysiology
April 9, 2025 at 1:53 PM
Cryo-EM reveals how cholesterol and sphingomyelin shape the structure and stability of a membrane pore formed by the toxin Fav.

Electrophysiology with the Orbit Mini confirms cholesterol reduces current noise.

🔗 Read more in the paper: ow.ly/sPmJ50VusCf

#CryoEM #MembraneBiophysics #Orbitmini
April 4, 2025 at 9:19 AM
𝗛𝗼𝘄 𝗱𝗼 𝗯𝗲𝘁𝗮-𝗹𝗮𝗰𝘁𝗮𝗺 𝗮𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗲𝗻𝘁𝗲𝗿 𝘁𝗵𝗲 𝗯𝗼𝗱𝘆?
And why does it matter for drug design?

Join us on May 14 as Joanne Parker (University of Oxford) presents new insights into the structure and function of PepT2, a key transporter in beta-lactam pharmacokinetics.
ow.ly/1mCL50Vo2j8

#MembraneTransport
April 2, 2025 at 9:22 AM
Understanding cardiac function needs more than one readout

This flyer shows how combining electrophysiology, contractility & viability data offers deeper insights into drug effects & disease models.

Discover more in the flyer: ow.ly/LGRs50VnV0o

#CardiacResearch #iPSC
March 25, 2025 at 2:12 PM
𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗣𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺!

From ion channels to drug discovery—discover what’s next in electrophysiology. Connect with leading experts in Napa Valley!

📅 Apr 30–May 1

𝗟𝗶𝗺𝗶𝘁𝗲𝗱-𝗧𝗶𝗺𝗲 𝗢𝗳𝗳𝗲𝗿: 𝟭𝟱% 𝗢𝗳𝗳 𝗧𝗶𝗰𝗸𝗲𝘁𝘀
Register now 🔗 ow.ly/SmfE50VgoHz

#MPS25 #MembranePhysiology
March 13, 2025 at 4:18 PM
Venom-derived toxins offer unique precision in ion channel research. We tested Huwentoxin-IV, TTX, GsMTx4 & α-Conotoxin MI on NaV1.7 and nAChR to explore their blocking effects. Want to learn more?
Read more in the full study: ow.ly/bKoG50Vgpy3
#IonChannels #DrugDiscovery #APC
March 12, 2025 at 2:32 PM
𝗛𝗲𝗮𝗱𝗶𝗻𝗴 𝘁𝗼 𝗡𝗲𝘅𝘁𝗚𝗲𝗻 𝗕𝗶𝗼𝗺𝗲𝗱 𝟮𝟬𝟮𝟱? 𝗟𝗲𝘁’𝘀 𝗖𝗼𝗻𝗻𝗲𝗰𝘁!

Meet us at Booth #60 to see AtlaZ in action—now GxP compliant! Get real-time, label-free insights into cell activity & viability and explore its impact on drug discovery & immuno-oncology.

🔗 ow.ly/nl0s50Vafhh

#NextGenBiomed #GxP #AtlaZ
March 5, 2025 at 1:18 PM
𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗖𝗮𝗿𝗱𝗶𝗮𝗰 𝗦𝗮𝗳𝗲𝘁𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝟮𝟬𝟮𝟱!

📅 May 21, 2025 | 🌍 Virtual

The symposium will bring together experts to discuss the latest advancements in safety pharmacology, cardiac physiology, and electrophysiology.

🔗 Learn more and register here 👉 ow.ly/VvWl50TPkbR

#CardiacSafety #Pharmacology
March 3, 2025 at 3:03 PM
AtlaZ now offers 𝗙𝗗𝗔 𝟮𝟭 𝗖𝗙𝗥 𝗣𝗮𝗿𝘁 𝟭𝟭 𝗰𝗼𝗺𝗽𝗹𝗶𝗮𝗻𝗰𝗲, ensuring secure, traceable, and audit-ready data for regulated research.

✅ Secure access & user tracking
✅ Audit trails & data integrity
✅ Compliance made simple

📄 Learn more: ow.ly/Oaln50V6Qk3

#CellAnalytics #GxPCompliance #21CFRPart11
February 27, 2025 at 10:31 AM
Our latest case study highlights how Frédéric Becq from the University of Poitiers uses automated patch-clamp technology to deepen our understanding of CFTR function and its interactions with drugs.

Read more here: www.nanion.de/wp-content/u...

#ionchannels #CFTR
February 26, 2025 at 5:12 PM
𝗛𝗼𝘄 𝗰𝗵𝗮𝗻𝗻𝗲𝗹𝗼𝗽𝗮𝘁𝗵𝗶𝗲𝘀 𝗮𝗿𝗲 𝗮𝗱𝘃𝗮𝗻𝗰𝗶𝗻𝗴 𝗱𝗿𝘂𝗴 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆? 🧬

Mutations in ion channels are linked to 1,300+ genetic disorders, many driving rare diseases. Understanding these mutations enables faster, more precise profiling, crucial for targeted therapies.

🔗 ow.ly/C0ST50V60SB

#RareDiseases #DrugDiscovery
February 25, 2025 at 2:24 PM
The INNOVATION consortium is shaping the next generation of researchers! At our recent meeting, students gained hands-on training while project leaders planned the next steps. Exciting progress in RBC ion channel research. Looking forward to future breakthroughs! 🚀
#IonChannels #Electrophysiology
February 19, 2025 at 1:25 PM
Silent Molecular Translocation

Some molecules move through nanopores without altering ionic currents, remaining invisible to traditional methods. The Orbit mini captures these silent events using optical + electrical recordings, unlocking new insights in biophysics & diagnostics ow.ly/HLFM50V16oS
February 17, 2025 at 1:51 PM
The Biophysical Society Meeting, starts today!

Check out our activities:

🔹 Ion channel drug discovery at our Satellite Meeting - Today!
🔹 Booth #509 – Live demos & latest innovations
🔹 Feb 17, 11:30 AM – Join us at our Exhibitor presentation
🔹 Don´t miss out on our Posters
lnkd.in/dPKd-Q2B

#BPS25
February 14, 2025 at 11:26 AM
Join us at the Membrane Physiology Symposium 2025!

📅 April 30 – May 1, 2025
📍 Napa Valley, CA

Two days of cutting-edge science, expert talks, and networking in a stunning location. Connect with top researchers and industry leaders.

🔗 Register now: lnkd.in/dW23dG-t

#MPS25 #MembranePhysiology
February 10, 2025 at 1:27 PM
Today, on World Cancer Day, we stand with everyone affected by cancer – the patients, the families, the researchers, the doctors, and all those who keep hoping for better days ahead.
www.linkedin.com/posts/nanion...

#worldcancerday #cancer #ionchannels #transporters
February 4, 2025 at 1:40 PM
Join us at #BPS2025! We're presenting six posters on ion channels, transporters, GPCRs & electrophysiology at the Biophysical Society Meeting in LA.

📅 Feb 16–18 | 📍 West Exhibit Hall
🔬 Stop by our posters & Booth #509 to chat!

ow.ly/SzmM50UR5sP

#Biophysics #Electrophysiology #IonChannels
January 31, 2025 at 1:52 PM
A new study introduces poly(C9) #nanopores, self-assembled from complement component 9, for precise single-protein analysis. poly(C9) nanopores enable highly sensitive and accurate characterization of a wide range
of natively folded proteins on a single molecule level.
www.nanion.de/news/self-as...
January 30, 2025 at 5:33 PM