Nancy Santiappillai
@nancyts.bsky.social
Postdoc fellow in the Keshari lab @MSKCC interested in cancer metabolism, mass spec, imaging, and therapeutics. 🇳🇿 -> 🇦🇺-> 🇺🇸🗽
Reposted by Nancy Santiappillai
reactant and product metabolite ratios revealed metabolic pathways differences between cancer subtypes and noncancer cell lines by @hoylipidlab.bsky.social @sydneyprecisionds.bsky.social @nancyts.bsky.social ➡️ www.embopress.org/doi/full/10....
July 3, 2025 at 10:11 AM
reactant and product metabolite ratios revealed metabolic pathways differences between cancer subtypes and noncancer cell lines by @hoylipidlab.bsky.social @sydneyprecisionds.bsky.social @nancyts.bsky.social ➡️ www.embopress.org/doi/full/10....
Reposted by Nancy Santiappillai
Incredibly proud of our latest publication in @molsystbiol.org led by @nancyts.bsky.social in collab w/ Jean Yang and Lake-Ee Quek - www.embopress.org/doi/full/10....
We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.
We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.
Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells | Molecular Systems Biology
imageimagePathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial
cell lines grown in their respective standard conditions reveals common and distinctive
metabolic signatur...
www.embopress.org
June 6, 2025 at 1:23 AM
Incredibly proud of our latest publication in @molsystbiol.org led by @nancyts.bsky.social in collab w/ Jean Yang and Lake-Ee Quek - www.embopress.org/doi/full/10....
We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.
We curated targeted metabolomic data into pathway-centric ratios and identified subclusters of cancer cells with distinct features.
Had a great time sharing our work on macrophage TNBC symbiosis at the NYAS Cancer and Metabolism symposium!
April 8, 2025 at 9:39 PM
Had a great time sharing our work on macrophage TNBC symbiosis at the NYAS Cancer and Metabolism symposium!
Reposted by Nancy Santiappillai
In @cp-cancercell.bsky.social, Schild et al. @mskcancercenter.bsky.social engineered T cells & CAR T cells to express the fructose-specific transporter GLUT5, improving T cell glycolytic flux & thus effector function in glucose-limited conditions.
📖 the #researchhighlight 👇
📖 the #researchhighlight 👇
Sweet success in CAR T cells - Nature Reviews Cancer
Glycolysis-dependent T cell function is hindered by glucose scarcity in the tumour microenvironment. Now in Cancer Cell, Schild et al. engineered T cells to utilize fructose via GLUT5, enhancing their metabolic activity and cytotoxicity.
bit.ly
April 1, 2025 at 2:53 PM
In @cp-cancercell.bsky.social, Schild et al. @mskcancercenter.bsky.social engineered T cells & CAR T cells to express the fructose-specific transporter GLUT5, improving T cell glycolytic flux & thus effector function in glucose-limited conditions.
📖 the #researchhighlight 👇
📖 the #researchhighlight 👇