Marcel van de Wouw, PhD
mvdwouw.bsky.social
Marcel van de Wouw, PhD
@mvdwouw.bsky.social
Microbiome Program Director at the Weston Family Foundation

Microbiome-gut-brain axis | Early life | Healthy aging | Canada
Reposted by Marcel van de Wouw, PhD
New paper with @statsepi.bsky.social and @deevybee.bsky.social in which we show there's really no evidence for a link between the gut microbiome and autism www.cell.com/neuron/fullt...
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism
Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...
www.cell.com
November 13, 2025 at 4:10 PM
Reposted by Marcel van de Wouw, PhD
Just out! ✨ Using a novel machine learning approach, we identify a developmental pathway by which the early life gut microbiome may shape mental health at school age via effects on functional brain development. This work can help identify microbial biomarkers of later health issues. 👉 rdcu.be/eNsUK
Childhood gut microbiome is linked to internalizing symptoms at school age via the functional connectome
Nature Communications - Here, the authors find that relative abundances of stress-sensitive gastrointestinal microbes at age 2 years predicts internalizing symptoms in middle childhood through...
rdcu.be
October 31, 2025 at 7:03 PM
Reposted by Marcel van de Wouw, PhD
Congrats to Yancong, Amrisha, Xochitl, Eric and all co-authors!!!
October 17, 2025 at 3:36 PM
Reposted by Marcel van de Wouw, PhD
Reposted by Marcel van de Wouw, PhD
Is a healthy microbiome one that is rich in phages? 🦠 Excited to share our paper out in Lancet Microbe with @bkoskella.bsky.social & @dholtappels.bsky.social where we test whether virome diversity can be used a broad signature of microbiome health 📈
New research article

Evaluation of bacteriophages as a signature of #microbiome health: a systematic review and meta-analysis

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #Phage #OpenAccess #OA
October 10, 2025 at 1:12 PM
Reposted by Marcel van de Wouw, PhD
Our third sponsored talk was given by Dr. Simon Hirota, co-director of the Canadian National Organoid Network (CNON). CNON is free to join and gives researchers access to protocols, in-person training, and help with organoid ordering and research. canadianorganoidnetwork.ca
September 24, 2025 at 1:42 PM
Reposted by Marcel van de Wouw, PhD
Multicenter RCT in @lancetgastrohep.bsky.social:
FMT (with live microbes) prevents recurrent C. diff far better than fecal filtrates.
Thanks to Dina Kao (@ualberta.bsky.social) & @tsbschm.bsky.social from
@apcmicrobiomeirel.bsky.social), and whole team.
🔗 authors.elsevier.com/c/1lphg8nByr...
September 23, 2025 at 4:55 PM
Reposted by Marcel van de Wouw, PhD
The Weston Family Foundation is proud to be a Platinum Sponsor of #HavingIMPACTT2025. Through their Microbiome Initiative, they support groundbreaking research that accelerates the application of the microbiome to transform healthy aging for all Canadians. Visit bit.ly/4na4thJ to learn more.
September 3, 2025 at 5:48 PM
Reposted by Marcel van de Wouw, PhD
💥Personalized C. difficile colonization risk prediction and probiotic therapy assessment in the human gut💥

I'm very excited about this work, driven by Alex Carr & co-supervised by @cdiener.com

@cp-cellsystems.bsky.social @isbscience.org @nitinbaliga.bsky.social

www.cell.com/cell-systems...

🧵...
Personalized Clostridioides difficile colonization risk prediction and probiotic therapy assessment in the human gut
Carr et al. show how microbial community-scale metabolic models (MCMMs) predict personalized Clostridioides difficile colonization risk and probiotic efficacy. MCMMs reveal key metabolic strategies ex...
www.cell.com
August 6, 2025 at 4:51 PM
Reposted by Marcel van de Wouw, PhD
Reposted by Marcel van de Wouw, PhD
Today is the last day to submit your abstract and get our early-bird registration rate for #HavingIMPACTT2025!
📣‼️DEADLINE EXTENDED: We have EXTENDED our early-bird registration & abstract submission deadline by ONE WEEK for our #HavingIMPACTT2025 microbiome symposium! This means you now have until Tuesday, July 22, 2025 to submit your abstract and take advantage of our early-bird registration rate!
July 22, 2025 at 5:45 PM
Reposted by Marcel van de Wouw, PhD
Exciting Senior Scientist 👩‍🔬 👨‍🔬 role available in my research group 🧠 🦠 - Closing date Tuesday 5th August 2025.

Please Share

@apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social
Full details here
my.corehr.com/pls/uccrecru...
July 7, 2025 at 11:20 AM
Reposted by Marcel van de Wouw, PhD
Just 3 weeks until our early-bird registration & abstract submission deadline for our #HavingIMPACTT2025 microbiome symposium on Sep 22-24, 2025 in Canmore, Canada! We have tons of awards and an incredible speaker lineup, so you don't want to miss out! www.impactt-microbiome.ca/having-impac...
June 24, 2025 at 6:11 PM
Reposted by Marcel van de Wouw, PhD
Led by Emily Wroot, I present our recent Comment in @natmicrobiol.nature.com

"Opportunities for microbiome-based therapeutics in preterm infants"

Hopefully this provides a timely insight for clinicians and researchers interested in preterm infants, and beyond!

www.nature.com/articles/s41...
Opportunities for microbiome-based therapeutics in preterm infants - Nature Microbiology
Microbial-based and microorganism-targeting therapies are emerging to prevent or treat preterm infant complications, but more preclinical research and clinical evidence is needed.
www.nature.com
May 20, 2025 at 1:48 PM
Reposted by Marcel van de Wouw, PhD
We are excited to share that we have SIXTEEN (16) awards for presenters this year at #HavingIMPACTT2025 - our most ever! Submit your abstract before our July 15, 2025 deadline, and remember to register early, as spaces are first-come first-served! www.impactt-microbiome.ca/having-impac...
May 20, 2025 at 11:45 PM
Reposted by Marcel van de Wouw, PhD
The FDA says that over the next 3–5 years it aims “to make animal studies the exception rather than the norm” for preclinical safety testing, starting with monoclonal antibodies and eventually encompassing all drugs. cen.acs.org/pharmaceutic...
FDA’s shift from animal testing opens doors for organoid makers
New policy could be a windfall for makers of nonanimal models
cen.acs.org
May 12, 2025 at 10:08 AM
Reposted by Marcel van de Wouw, PhD
PLEASE SHARE We’re hiring a contract #bioinformatician (research officer) to analyse #microbiome data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics

topjobs-teagasc.thehirelab.com/LiveJobs/Job...
May 12, 2025 at 10:12 AM
Reposted by Marcel van de Wouw, PhD
📢 Just launched!

FREE educational modules about the #microbiome - including one about #breastfeeding.

This flexible curriculum includes slide decks, speaker notes, learning activities & recorded lectures.

Please use, share, and send feedback!

cifar.ca/cifarnews/20...
Humans & the Microbiome: Educational Modules for Public Health Professionals - CIFAR
The human microbiome (microbes living in and on us, and their genomes) is a critical yet often overlooked factor influencing public health. Public health has […]
cifar.ca
May 6, 2025 at 8:10 PM
Reposted by Marcel van de Wouw, PhD
A lot of what looks like microbial engraftment after FMT might actually be noise. Using placebo sequencing and culture-enriched metagenomics, we sort signal from noise. Our latest from the Surette lab: www.nature.com/articles/s41... @surettem.bsky.social @mcmasteruniversity.bsky.social
Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise - Nature Communications
Here, the authors profile bacterial engraftment in UC patients receiving FMT from a single donor and placebo samples to estimate noise, showing a significant level of false-positive engraftment, which...
www.nature.com
April 25, 2025 at 3:22 PM
📢 Funding announcement: Our POP2025 call for applications is now open!

The Weston Family Foundation is funding Canadian researchers in advancing microbiome-based interventions to improve therapeutic responses or health outcomes.

For more info and to apply now: westonfoundation.ca/grant_call/p...
April 25, 2025 at 12:59 PM
Reposted by Marcel van de Wouw, PhD
New research links fibromyalgia pain to the gut microbiome. Transplanting healthy gut bacteria reduced pain in mice—and in a small clinical trial, improved symptoms in women.
@karapedsgastrodoc.bsky.social
@nyupainresearch.bsky.social
www.cell.com/neuron/fullt...
The gut microbiota promotes pain in fibromyalgia
Cai et al. revealed that transplanting gut microbiota from women with fibromyalgia—a chronic widespread pain condition of unknown etiology—into mice induces pain. It also induces phenotypes commonly o...
www.cell.com
April 24, 2025 at 8:28 PM
Reposted by Marcel van de Wouw, PhD
Excited to share a new publication out!

“Acute Stress-induced Alterations in Short-Chain Fatty Acids: Implications for the Intestinal and Blood Brain Barriers”.

@jfcryan.bsky.social
@apcmicrobiomeirel.bsky.social
@sarah-janeleigh.bsky.social

www.sciencedirect.com/science/arti...
Acute Stress-induced Alterations in Short-Chain Fatty Acids: Implications for the Intestinal and Blood Brain Barriers
Unravelling the features of the whole-body response to acute stress exposures is critical to understand this neglected building block of chronic stres…
www.sciencedirect.com
April 20, 2025 at 9:18 AM
Reposted by Marcel van de Wouw, PhD
Commentary published on Microbiome Stewardship!

Our collaborative team of researchers (bioethicists (Kieran and Diego), bioinformaticians (Rob), host microbial ecologists (Sue and Emma), and soil microbial ecologists (Mallory), had our first co-authored paper published in mSystems! Our paper is a…
Commentary published on Microbiome Stewardship!
Our collaborative team of researchers (bioethicists (Kieran and Diego), bioinformaticians (Rob), host microbial ecologists (Sue and Emma), and soil microbial ecologists (Mallory), had our first co-authored paper published in mSystems! Our paper is a commentary on the concept and need for microbiome stewardship, and outlines the research and policy priorities that are the focus of our ongoing research.
sueishaqlab.org
April 16, 2025 at 4:02 PM
Reposted by Marcel van de Wouw, PhD
Eat to support your #microbiome. Anissa Armet and I are thrilled to announce our FREE 'science cookbook' on The NiMe Diet, bit.ly/41BV0HW, covering the story behind our research published in @cp-cell.bsky.social. If around Cork, register freely for an evening with the Creators on March 10th.
The NiMe Diet: Scientific Principles and... | ERA
Industrialized diets – high in processed foods and low in fibre – disrupt the gut microbiome and predispose us to chronic diseases, such...
bit.ly
March 3, 2025 at 9:52 AM