Sean Murphy
@murphyslaw1987.bsky.social
Philosopher w/ focus on disease causation (esp. clusters). I completed Mark Purdey’s research project by identifying the true environmental causes (oil pollution, pesticides, mercury, & mycotoxins) of “Huntington’s Disease” at Lake Maracaibo.
Pinned
Lake Maracaibo Huntington’s Disease cluster (the most important cluster of them all when it comes to challenging the genetic consensus), petroleum pollution, and heritable genetic mutations.
This is a new insight? I thought this was already recognized. In any event, when posting about the cigarette/Huntington’s connection in the past, I realized that cigarette smoking means mercury exposure. I’m sure that’s just a coincidence, though.
🚬 New insight: smoking may accelerate symptom progression in Huntington’s disease, with smokers experiencing a faster decline. Lifestyle counselling could be key to slowing neurological deterioration.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #HuntingtonsDisease #Neurodegeneration
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #HuntingtonsDisease #Neurodegeneration
Smoking Tied to Faster Huntington’s Decline
Analysis of Enroll-HD shows smoking is linked to earlier Huntington’s disease onset in women and faster motor and cognitive decline, supporting cessation advice for HD gene carriers.In Enroll-HD, smok...
www.emjreviews.com
October 16, 2025 at 1:37 PM
This is a new insight? I thought this was already recognized. In any event, when posting about the cigarette/Huntington’s connection in the past, I realized that cigarette smoking means mercury exposure. I’m sure that’s just a coincidence, though.
Anybody have any idea what would possess a scientist with impressive credentials to erroneously claim that the results of some study which were carefully measured and reported by multiple researchers were merely self-reported by their patient, instead? Asking for Dr. Rachel Harding. Thanks.
September 30, 2025 at 4:01 AM
Anybody have any idea what would possess a scientist with impressive credentials to erroneously claim that the results of some study which were carefully measured and reported by multiple researchers were merely self-reported by their patient, instead? Asking for Dr. Rachel Harding. Thanks.
Another good reason for questioning the alleged success of AMT-130 in slowing the progression of Huntington’s Disease: Ed Wild’s involvement.
September 28, 2025 at 2:38 PM
Another good reason for questioning the alleged success of AMT-130 in slowing the progression of Huntington’s Disease: Ed Wild’s involvement.
My take on the alleged Huntington’s Disease breakthrough:
September 25, 2025 at 9:25 PM
My take on the alleged Huntington’s Disease breakthrough:
The Rouen ducks have grown a bit:
August 10, 2025 at 1:19 PM
The Rouen ducks have grown a bit:
Since smelling salts have apparently just been banned from the NFL, I thought I’d share my take on them from years ago, and their (thus far officially unacknowledged) potential link to CTE symptoms. CTE researchers never told me why I was wrong, only insisted that I must be. Go figure.
August 6, 2025 at 4:45 PM
Since smelling salts have apparently just been banned from the NFL, I thought I’d share my take on them from years ago, and their (thus far officially unacknowledged) potential link to CTE symptoms. CTE researchers never told me why I was wrong, only insisted that I must be. Go figure.
What I’ve been busy with lately:
July 16, 2025 at 8:06 AM
What I’ve been busy with lately:
Reposted by Sean Murphy
Speaking of Mount Isa and genetic mutations in response to pollution problems:
amp.abc.net.au/article/1029...
amp.abc.net.au/article/1029...
June 9, 2025 at 5:35 AM
Speaking of Mount Isa and genetic mutations in response to pollution problems:
amp.abc.net.au/article/1029...
amp.abc.net.au/article/1029...
Reposted by Sean Murphy
Although it still officially has nothing to do with what’s making the Indigenous population there sick (w/ Groote Eylandt Syndrome/MJD/SCA3), Purdey’s compelling Cawtian analysis notwithstanding, the excessive manganese exposure on Groote is now being recognized as detrimental to quoll health. Hmm…
June 11, 2025 at 6:36 AM
Although it still officially has nothing to do with what’s making the Indigenous population there sick (w/ Groote Eylandt Syndrome/MJD/SCA3), Purdey’s compelling Cawtian analysis notwithstanding, the excessive manganese exposure on Groote is now being recognized as detrimental to quoll health. Hmm…
Reposted by Sean Murphy
‘A timebomb’: could a French mine full of waste poison the drinking water of millions?
Then consider the implications for a #nuclear waste 'disposal' facility leaking over time ...
www.theguardian.com/environment/...
Then consider the implications for a #nuclear waste 'disposal' facility leaking over time ...
www.theguardian.com/environment/...
‘A timebomb’: could a French mine full of waste poison the drinking water of millions?
Scientists fear thousands of tonnes of chemicals dumped in mining tunnels in Alsace may seep into an aquifer with devastating consequences for people and wildlife
www.theguardian.com
June 23, 2025 at 8:13 AM
‘A timebomb’: could a French mine full of waste poison the drinking water of millions?
Then consider the implications for a #nuclear waste 'disposal' facility leaking over time ...
www.theguardian.com/environment/...
Then consider the implications for a #nuclear waste 'disposal' facility leaking over time ...
www.theguardian.com/environment/...
If you’re not familiar with the origin story of Chronic Wasting Disease, and how it supports my take on prion diseases more generally, here’s Mark Purdey breaking it down for you:
June 22, 2025 at 2:03 PM
If you’re not familiar with the origin story of Chronic Wasting Disease, and how it supports my take on prion diseases more generally, here’s Mark Purdey breaking it down for you:
Although it wouldn’t surprise me if Shell used this same excuse, too, I might have been thinking of PDVSA, instead. My bad:
June 22, 2025 at 1:44 PM
Although it wouldn’t surprise me if Shell used this same excuse, too, I might have been thinking of PDVSA, instead. My bad:
Reposted by Sean Murphy
You follow?
Fishing population+oil pollution (from Shell, no less)=heavy metal (like mercury) exposure/poisoning, thus resulting in neurodegenerative diseases like Parkinson’s and Alzheimer’s in genetically susceptible individuals.
I’m sure it’s different at Lake Maracaibo, though, right? Pfft…
Fishing population+oil pollution (from Shell, no less)=heavy metal (like mercury) exposure/poisoning, thus resulting in neurodegenerative diseases like Parkinson’s and Alzheimer’s in genetically susceptible individuals.
I’m sure it’s different at Lake Maracaibo, though, right? Pfft…
June 3, 2025 at 8:01 AM
You follow?
Fishing population+oil pollution (from Shell, no less)=heavy metal (like mercury) exposure/poisoning, thus resulting in neurodegenerative diseases like Parkinson’s and Alzheimer’s in genetically susceptible individuals.
I’m sure it’s different at Lake Maracaibo, though, right? Pfft…
Fishing population+oil pollution (from Shell, no less)=heavy metal (like mercury) exposure/poisoning, thus resulting in neurodegenerative diseases like Parkinson’s and Alzheimer’s in genetically susceptible individuals.
I’m sure it’s different at Lake Maracaibo, though, right? Pfft…
Reposted by Sean Murphy
I just recently sent an email through ResearchGate asking for full access to this paper, but since I don’t like my odds, and am admittedly a bit impatient, is there anybody who has access to it and willing to share? I’d very much appreciate it. Thanks.
pubmed.ncbi.nlm.nih.gov/8414025/
pubmed.ncbi.nlm.nih.gov/8414025/
June 5, 2025 at 1:47 PM
I just recently sent an email through ResearchGate asking for full access to this paper, but since I don’t like my odds, and am admittedly a bit impatient, is there anybody who has access to it and willing to share? I’d very much appreciate it. Thanks.
pubmed.ncbi.nlm.nih.gov/8414025/
pubmed.ncbi.nlm.nih.gov/8414025/
Reposted by Sean Murphy
An interesting exchange I had a few years ago with one of my friends diagnosed with the Huntington’s Disease CAG expansion mutation.
Coincidence, or causation?
Coincidence, or causation?
June 9, 2025 at 5:31 AM
An interesting exchange I had a few years ago with one of my friends diagnosed with the Huntington’s Disease CAG expansion mutation.
Coincidence, or causation?
Coincidence, or causation?
Reposted by Sean Murphy
If you don’t have a problem with what BHP did (namely, threatened to sue researchers who implicated manganese as the cause of Groote Eylandt Syndrome), I’m not sure why’d you’d find this any more objectionable.
A new chapter in the history of science denial:
A Manufacturer Sues to Stop a Discussion. www.nytimes.com/2025/06/17/c...
A Manufacturer Sues to Stop a Discussion. www.nytimes.com/2025/06/17/c...
Is Fake Grass Safe? A Manufacturer Sues to Stop a Discussion.
www.nytimes.com
June 19, 2025 at 9:14 AM
If you don’t have a problem with what BHP did (namely, threatened to sue researchers who implicated manganese as the cause of Groote Eylandt Syndrome), I’m not sure why’d you’d find this any more objectionable.
Reposted by Sean Murphy
New paper with Ally Clonch highlights how urban environmental stressors like air pollution, heat, and chronic noise exposure are fueling Alzheimer's, Parkinson's, and other neurodegenerative diseases by provoking inflammation in the brain. 🧵
utppublishing.com/doi/10.3138/...
utppublishing.com/doi/10.3138/...
Neurotoxic Metropolis: Navigating Inflammatory Risks to Brain Health in Urban Environmental Planning | Journal of City Climate Policy and Economy
Urban areas are epicentres of environmental stressors that pose significant risks to human health. Here, we highlight the manners in which these exposures—primarily air pollution, heat stress, and noi...
utppublishing.com
June 2, 2025 at 4:44 PM
New paper with Ally Clonch highlights how urban environmental stressors like air pollution, heat, and chronic noise exposure are fueling Alzheimer's, Parkinson's, and other neurodegenerative diseases by provoking inflammation in the brain. 🧵
utppublishing.com/doi/10.3138/...
utppublishing.com/doi/10.3138/...
Reposted by Sean Murphy
ChatGPT fails the Turing Test because it sounds too clever.
As expected: "Despite ChatGPT reportedly outperforming 99.9% of humans in a Verbal IQ test, it falls short of passing the Turing Test. In 9 out of the 10 tests conducted, the interrogators successfully identified ChatGPT-4 and the human participant."
link.springer.com/article/10.1...
link.springer.com/article/10.1...
ChatGPT-4 in the Turing Test - Minds and Machines
There has been considerable optimistic speculation on how well ChatGPT-4 would perform in a Turing Test. However, no minimally serious implementation of the test has been reported to have been carried...
link.springer.com
January 28, 2025 at 10:49 PM
ChatGPT fails the Turing Test because it sounds too clever.
Reposted by Sean Murphy
Here’s what I put together for you on Groote Eylandt Syndrome/MJD/SCA3 @maaikeverbruggen.bsky.social. Not my best work, but I think it covers enough of what it needs to. Along with the timeline I’m reposting (which contains my sources), here’s pages 1-4 (of 12) of what I wrote:
May 24, 2025 at 6:50 AM
Here’s what I put together for you on Groote Eylandt Syndrome/MJD/SCA3 @maaikeverbruggen.bsky.social. Not my best work, but I think it covers enough of what it needs to. Along with the timeline I’m reposting (which contains my sources), here’s pages 1-4 (of 12) of what I wrote:
Reposted by Sean Murphy
Still think my intro (post linked to) is better, since I’m not ignoring the mercury pollution and pesticide exposure in Antioquia like everybody else who’d have you believe in genetic determinism, including Smith and Lopera. But what do I know?
bsky.app/profile/murp...
bsky.app/profile/murp...
Book Review: The Mystery of Alzheimer’s Disease in Rural Colombia - good intro to @jennieerinsmith.bsky.social's insightful and poignant work via @undark.org undark.org/2025/06/13/b...
Book Review: The Mystery of Alzheimer’s Disease in Rural Colombia
Jennie Erin Smith’s “Valley of Forgetting” explores the genetic roots of early-onset dementia plaguing a mountain region.
undark.org
June 14, 2025 at 12:43 PM
Still think my intro (post linked to) is better, since I’m not ignoring the mercury pollution and pesticide exposure in Antioquia like everybody else who’d have you believe in genetic determinism, including Smith and Lopera. But what do I know?
bsky.app/profile/murp...
bsky.app/profile/murp...
Reposted by Sean Murphy
For whatever reason, Williams, like Kwakye, fails to mention that the clustering in Venezuela (which she does acknowledge) also impacts a fishing population. Considering that they both have to know as much (it’s no secret, after all), why would they omit it after the Minamata comparison? Anyone?
June 15, 2025 at 7:58 AM
For whatever reason, Williams, like Kwakye, fails to mention that the clustering in Venezuela (which she does acknowledge) also impacts a fishing population. Considering that they both have to know as much (it’s no secret, after all), why would they omit it after the Minamata comparison? Anyone?
If you don’t have a problem with what BHP did (namely, threatened to sue researchers who implicated manganese as the cause of Groote Eylandt Syndrome), I’m not sure why’d you’d find this any more objectionable.
A new chapter in the history of science denial:
A Manufacturer Sues to Stop a Discussion. www.nytimes.com/2025/06/17/c...
A Manufacturer Sues to Stop a Discussion. www.nytimes.com/2025/06/17/c...
Is Fake Grass Safe? A Manufacturer Sues to Stop a Discussion.
www.nytimes.com
June 19, 2025 at 9:14 AM
If you don’t have a problem with what BHP did (namely, threatened to sue researchers who implicated manganese as the cause of Groote Eylandt Syndrome), I’m not sure why’d you’d find this any more objectionable.
Reposted by Sean Murphy
Remember when I contracted you a few years back (on LinkedIn) regarding BHP threatening to sue researchers who blamed Groote Eylandt Syndrome on manganese, before they funded the genetic research that entirely ignored their pollution? I’d still very much like to hear your take on this. Thanks.
June 19, 2025 at 9:09 AM
Remember when I contracted you a few years back (on LinkedIn) regarding BHP threatening to sue researchers who blamed Groote Eylandt Syndrome on manganese, before they funded the genetic research that entirely ignored their pollution? I’d still very much like to hear your take on this. Thanks.
Reposted by Sean Murphy
Trial Shows No Added Benefit From Antibiotics Before Appendectomy
www.emjreviews.com/gastroentero...
www.emjreviews.com/gastroentero...
Trial Shows No Added Benefit From Antibiotics Before Appendectomy
A major trial shows no significant difference in outcomes for patients with uncomplicated appendicitis who wait for surgery without antibiotics.
www.emjreviews.com
June 18, 2025 at 6:02 PM
Trial Shows No Added Benefit From Antibiotics Before Appendectomy
www.emjreviews.com/gastroentero...
www.emjreviews.com/gastroentero...