Anaya Malik
@amjeditor.bsky.social
Editor & VP of Content of the American Medical Journal. Publisher of open access eJournals in Dermatology, Neurology, Respiratory, Oncology, Microbiology & ID, and Rheumatology content. Free subscription: https://www.emjreviews.com/en-us/amj/mailing-list/
💨 New data show lung cancer survival has risen to nearly 30%, driven by screening and precision medicine. Yet experts caution that funding cuts could slow advances in prevention, diagnosis, and equitable access to care.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory
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#AMJRespiratory
Lung Cancer Survival Improves, but Funding Threats Loom
Lung cancer survival rates are rising across the U.S. thanks to early detection and new treatments, but funding cuts could jeopardize these life-saving advancements.
www.emjreviews.com
November 11, 2025 at 5:28 PM
💨 New data show lung cancer survival has risen to nearly 30%, driven by screening and precision medicine. Yet experts caution that funding cuts could slow advances in prevention, diagnosis, and equitable access to care.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory
📊 COVID-19 disrupted cancer patterns, and men were hit harder. National data reveal sharper declines in cancer diagnoses among men than women during the pandemic, altering long-term detection and prevention trends.
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
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#AMJOncology #CancerResearch
COVID-19 Altered Cancer Rates Differently for Men and Women
A population-based study found enduring sex differences in cancer incidence after COVID-19, with males and females showing distinct postpandemic patterns across tumor types.
www.emjreviews.com
November 11, 2025 at 5:25 PM
📊 COVID-19 disrupted cancer patterns, and men were hit harder. National data reveal sharper declines in cancer diagnoses among men than women during the pandemic, altering long-term detection and prevention trends.
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
🧠 New data reveal rural Americans aged 45+ face higher rates of modifiable dementia risk factors such as obesity, diabetes, hearing loss underscoring the need for targeted prevention and better access to care.
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #PublicHealth #DementiaPrevention
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#AMJMicrobiology #PublicHealth #DementiaPrevention
Rural Americans Face Higher Burden of Dementia Risk
New data reveal U.S. adults in rural areas face higher rates of modifiable dementia risk factors, underscoring the need for targeted prevention strategies.
www.emjreviews.com
November 11, 2025 at 2:19 PM
🧠 New data reveal rural Americans aged 45+ face higher rates of modifiable dementia risk factors such as obesity, diabetes, hearing loss underscoring the need for targeted prevention and better access to care.
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #PublicHealth #DementiaPrevention
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #PublicHealth #DementiaPrevention
🧴☀️ New finding: Sunscreens purchased online sometimes contain no UV-filter actives whatsoever. That means zero UVB or UVA protection, branding only.
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#AMJDermatology #SkinHealth
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#AMJDermatology #SkinHealth
Poor-Quality Sunscreens Show No UV Protection
New analysis shows poor-quality sunscreen products purchased online can lack UV filters entirely and therefore provide no photoprotection, placing users at substantial cutaneous risk.
www.emjreviews.com
November 10, 2025 at 5:32 PM
🧴☀️ New finding: Sunscreens purchased online sometimes contain no UV-filter actives whatsoever. That means zero UVB or UVA protection, branding only.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #SkinHealth
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #SkinHealth
🤖 Artificial neural networks predicted overall and progression-free survival in adults aged 65+ with head and neck cancer after chemoradiation, using standard clinical variables across 19 global centers.
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
AI Outcome Prediction for Chemoradiation in Head and Neck Cancer
Artificial neural networks predicted overall and progression-free survival after chemoradiation in older adults with head and neck cancer, enabling pragmatic risk stratification to inform personalized...
www.emjreviews.com
November 6, 2025 at 8:00 PM
🤖 Artificial neural networks predicted overall and progression-free survival in adults aged 65+ with head and neck cancer after chemoradiation, using standard clinical variables across 19 global centers.
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
www.emjreviews.com/en-us/amj/on...
#AMJOncology #CancerResearch
💨 Inspiratory muscle training appears to enhance exercise tolerance in adults with post-COVID-19 syndrome. Trials show gains in inspiratory strength, diaphragmatic thickness, and six-minute walk distance.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #PostCOVID
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#AMJRespiratory #PostCOVID
Inspiratory Muscle Training May Boost Post-COVID Exercise Tolerance
Systematic review suggests inspiratory muscle training improves exercise tolerance and respiratory parameters in post-COVID-19 syndrome, though protocols vary and larger standardized trials are needed...
www.emjreviews.com
November 6, 2025 at 7:59 PM
💨 Inspiratory muscle training appears to enhance exercise tolerance in adults with post-COVID-19 syndrome. Trials show gains in inspiratory strength, diaphragmatic thickness, and six-minute walk distance.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #PostCOVID
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #PostCOVID
📈 Achalasia hospitalizations surged over a decade. Rising admissions signal burden and care gaps in motility disorder.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
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#AMJNeurology
Achalasia Hospitalizations Reflect Major Decade Shift
This U.S. trend analysis of achalasia hospitalizations reports rising POEM adoption more comorbid patients and increasing cost pressures across a decade of inpatient care.
www.emjreviews.com
November 6, 2025 at 7:58 PM
📈 Achalasia hospitalizations surged over a decade. Rising admissions signal burden and care gaps in motility disorder.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
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#AMJNeurology
🎯🔍 Gaps in GP confidence are shaping dermatology referrals. Targeted training could improve triage quality. Study shows modules aid.
www.emjreviews.com/dermatology/...
#AMJDermatology
www.emjreviews.com/dermatology/...
#AMJDermatology
Improving Dermatology Referrals: Addressing Gaps in Doctor Confidence
Foundation doctors report limited confidence in dermatology skills, with mismatched expectations from dermatologists. This study highlights the need for better dermatology training and clearer referra...
www.emjreviews.com
November 5, 2025 at 12:51 PM
🎯🔍 Gaps in GP confidence are shaping dermatology referrals. Targeted training could improve triage quality. Study shows modules aid.
www.emjreviews.com/dermatology/...
#AMJDermatology
www.emjreviews.com/dermatology/...
#AMJDermatology
🧠 Why do outcomes vary in pediatric cerebral malaria? Researchers found that deaths arise from diverse causes, not just cerebral herniation, but also systemic organ failure, suggesting new directions for targeted interventions.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
Clinical Drivers of Outcome in Cerebral Malaria
Cause-specific mortality patterns in paediatric cerebral malaria revealed multiple distinct immediate causes of death indicating possible dilution of brain-focused therapeutic effects in clinical tria...
www.emjreviews.com
November 4, 2025 at 10:51 AM
🧠 Why do outcomes vary in pediatric cerebral malaria? Researchers found that deaths arise from diverse causes, not just cerebral herniation, but also systemic organ failure, suggesting new directions for targeted interventions.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology
🦠 New AMJ infographic: Post-exposure prophylaxis must evolve with shifting COVID-19 variants...
emjreviews.com/en-us/amj/mi...
The publication of this infographic was funded by an unrestricted educational grant from Shionogi Inc. (US).
#AMJMicrobiology #InfectiousDiseases
emjreviews.com/en-us/amj/mi...
The publication of this infographic was funded by an unrestricted educational grant from Shionogi Inc. (US).
#AMJMicrobiology #InfectiousDiseases
Role of Post-Exposure Prophylaxis in COVID-19
Hospitalizations due to COVID-19 have declined, but SARS-CoV-2 transmission remains high in high-exposure settings and...
emjreviews.com
November 3, 2025 at 12:45 PM
🦠 New AMJ infographic: Post-exposure prophylaxis must evolve with shifting COVID-19 variants...
emjreviews.com/en-us/amj/mi...
The publication of this infographic was funded by an unrestricted educational grant from Shionogi Inc. (US).
#AMJMicrobiology #InfectiousDiseases
emjreviews.com/en-us/amj/mi...
The publication of this infographic was funded by an unrestricted educational grant from Shionogi Inc. (US).
#AMJMicrobiology #InfectiousDiseases
🦴✨ Bone manipulation may enhance wound healing by boosting microcirculation and tissue repair. Study links effect to angiogenesis.
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
How Does Bone Manipulation Influence Wound Healing?
This case series reports limb salvage with transverse tibial transport showing complete healing in recalcitrant diabetic foot ulcers with no pin site infections.
www.emjreviews.com
November 3, 2025 at 11:28 AM
🦴✨ Bone manipulation may enhance wound healing by boosting microcirculation and tissue repair. Study links effect to angiogenesis.
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
💡 Three monthly autologous platelet-rich plasma injections significantly improved hair density, reduced shedding and raised patient satisfaction scores in moderate to severe androgenetic alopecia. Safe, promising and minimally invasive.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #HairLoss
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #HairLoss
Platelet-Rich Plasma Injections Boost Hair Growth
A prospective trial found that autologous platelet-rich plasma injections significantly improved hair density and satisfaction in patients with androgenetic alopecia.
www.emjreviews.com
October 31, 2025 at 4:19 PM
💡 Three monthly autologous platelet-rich plasma injections significantly improved hair density, reduced shedding and raised patient satisfaction scores in moderate to severe androgenetic alopecia. Safe, promising and minimally invasive.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #HairLoss
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #HairLoss
🧠 Prior concussion, not just years in contact sport, shows clear ties to altered cortical microstructure in collegiate athletes, hinting at early neurotrauma risk.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #SportsMedicine
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#AMJNeurology #SportsMedicine
Contact Sports and Concussion Affect Brain Structure
New imaging data suggest prior concussion alters cortical microstructure and surface area in young athletes, highlighting early neurotrauma effects in contact sports.
www.emjreviews.com
October 28, 2025 at 3:08 PM
🧠 Prior concussion, not just years in contact sport, shows clear ties to altered cortical microstructure in collegiate athletes, hinting at early neurotrauma risk.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #SportsMedicine
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #SportsMedicine
🧬 Understanding stubborn lung infection: a new study reveals how M. avium frequently reinfects, evolves and resists therapy in chronic pulmonary disease, highlighting critical challenges for clinicians.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #InfectiousDiseases #PulmonaryDisease #NTM
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #InfectiousDiseases #PulmonaryDisease #NTM
Why Stubborn Lung Infections Persist Despite Therapy
Whole genome sequencing reveals frequent strain acquisition and adaptive evolution of Mycobacterium avium during chronic infection, highlighting virulence and resistance targets for intervention.
www.emjreviews.com
October 28, 2025 at 3:07 PM
🧬 Understanding stubborn lung infection: a new study reveals how M. avium frequently reinfects, evolves and resists therapy in chronic pulmonary disease, highlighting critical challenges for clinicians.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #InfectiousDiseases #PulmonaryDisease #NTM
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #InfectiousDiseases #PulmonaryDisease #NTM
As #ACRConvergence unfolds, one session really stood out “Driving CAR-T into the Future.”
With discussion of next-gen #Bcell targets (CD19, CD20, BCMA, autoreactive subsets), the field is moving from broad depletion to tailored immune precision.
#Lupus #AutoimmuneDisease #CARTcells
With discussion of next-gen #Bcell targets (CD19, CD20, BCMA, autoreactive subsets), the field is moving from broad depletion to tailored immune precision.
#Lupus #AutoimmuneDisease #CARTcells
October 26, 2025 at 5:09 PM
As #ACRConvergence unfolds, one session really stood out “Driving CAR-T into the Future.”
With discussion of next-gen #Bcell targets (CD19, CD20, BCMA, autoreactive subsets), the field is moving from broad depletion to tailored immune precision.
#Lupus #AutoimmuneDisease #CARTcells
With discussion of next-gen #Bcell targets (CD19, CD20, BCMA, autoreactive subsets), the field is moving from broad depletion to tailored immune precision.
#Lupus #AutoimmuneDisease #CARTcells
🧬 New study finds TNF inhibitors do not accelerate weight gain in psoriatic arthritis. In fact, the pace of weight increase slowed after treatment, offering reassurance for long-term metabolic management.
www.emjreviews.com/rheumatology...
#AMJRheumatology #AutoimmuneDisease #PsoriaticArthritis
www.emjreviews.com/rheumatology...
#AMJRheumatology #AutoimmuneDisease #PsoriaticArthritis
Weight Gain Rates Stabilize After TNF Inhibitor Initiation
Tumor necrosis factor inhibitors were not linked to additional weight gain in patients with psoriatic arthritis when age-related changes were considered.
www.emjreviews.com
October 24, 2025 at 5:54 PM
🧬 New study finds TNF inhibitors do not accelerate weight gain in psoriatic arthritis. In fact, the pace of weight increase slowed after treatment, offering reassurance for long-term metabolic management.
www.emjreviews.com/rheumatology...
#AMJRheumatology #AutoimmuneDisease #PsoriaticArthritis
www.emjreviews.com/rheumatology...
#AMJRheumatology #AutoimmuneDisease #PsoriaticArthritis
🤖🚬 Dermatologist-guided AI predicts how smoking accelerates facial aging, visualizing wrinkle formation, pigmentation, and skin texture changes over 15 years. A powerful tool for prevention and patient education.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #SkinAging #AIinMedicine #Smoking
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#AMJDermatology #SkinAging #AIinMedicine #Smoking
AI Model Predicts Facial Aging from Tobacco Use
A dermatologist-informed AI model accurately predicts and visualizes how tobacco use accelerates facial aging, offering a new tool for prevention and patient education.
www.emjreviews.com
October 24, 2025 at 5:36 PM
🤖🚬 Dermatologist-guided AI predicts how smoking accelerates facial aging, visualizing wrinkle formation, pigmentation, and skin texture changes over 15 years. A powerful tool for prevention and patient education.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #SkinAging #AIinMedicine #Smoking
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #SkinAging #AIinMedicine #Smoking
🧬 At #IDWeek, a major study shows that vaccinating infants for RSV right after birth is safe and yields high antibody levels, even when mothers received RSV vaccination during pregnancy.
www.emjreviews.com/microbiology...
#AMJMicrobiology #InfectiousDiseases #RSV #Pediatrics
www.emjreviews.com/microbiology...
#AMJMicrobiology #InfectiousDiseases #RSV #Pediatrics
IDWeek 2025: RSV Shot After Birth Sparks Powerful Immunity
A U.S. study finds RSV immunization after birth is safe and provides strong antibody protection in infants, regardless of maternal vaccination status.
www.emjreviews.com
October 23, 2025 at 3:32 PM
🧬 At #IDWeek, a major study shows that vaccinating infants for RSV right after birth is safe and yields high antibody levels, even when mothers received RSV vaccination during pregnancy.
www.emjreviews.com/microbiology...
#AMJMicrobiology #InfectiousDiseases #RSV #Pediatrics
www.emjreviews.com/microbiology...
#AMJMicrobiology #InfectiousDiseases #RSV #Pediatrics
💉 GLP-1 receptor agonists may protect against right heart failure and pulmonary hypertension in people with obesity, showing promising cardiovascular benefits that extend beyond weight loss, new research reveals.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #Cardiology #GLP1 #Obesity
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #Cardiology #GLP1 #Obesity
CHEST 2025: GLP-1 Receptor Agonists Cut Right Heart Failure Risk
In pulmonary arterial hypertension, GLP-1 receptor agonists significantly lowered the risk of right heart failure compared with SGLT2 inhibitors, suggesting enhanced cardioprotective potential.
www.emjreviews.com
October 23, 2025 at 3:22 PM
💉 GLP-1 receptor agonists may protect against right heart failure and pulmonary hypertension in people with obesity, showing promising cardiovascular benefits that extend beyond weight loss, new research reveals.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #Cardiology #GLP1 #Obesity
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #Cardiology #GLP1 #Obesity
🧠 Improving transitions means improving outcomes. New evidence shows care coordination for head and neck cancer patients often falls short, especially between diagnosis, surgery, and radiation therapy. Read more on how teams can bridge the gap.
www.emjreviews.com/en-us/amj/on...
#AMJOncology
www.emjreviews.com/en-us/amj/on...
#AMJOncology
Improving Outcomes Through Coordinated Head and Neck Care
A scoping review reveals key gaps in transitions in care among head and neck cancer patients, urging stronger coordination between multidisciplinary teams to improve outcomes.
www.emjreviews.com
October 23, 2025 at 2:54 PM
🧠 Improving transitions means improving outcomes. New evidence shows care coordination for head and neck cancer patients often falls short, especially between diagnosis, surgery, and radiation therapy. Read more on how teams can bridge the gap.
www.emjreviews.com/en-us/amj/on...
#AMJOncology
www.emjreviews.com/en-us/amj/on...
#AMJOncology
🧠💡 A new study finds that combining brain stimulation with immersive VR training can markedly improve attention and cognitive control, offering a powerful, non-invasive approach to enhance brain function.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #CognitiveHealth #Neurorehabilitation #VR
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #CognitiveHealth #Neurorehabilitation #VR
Combined Brain Stimulation and VR Improves Attention
A single session combining transcranial direct current stimulation and virtual reality mindfulness reduced autonomic arousal and may improve attention control, suggesting potential benefits for cognit...
www.emjreviews.com
October 23, 2025 at 12:23 PM
🧠💡 A new study finds that combining brain stimulation with immersive VR training can markedly improve attention and cognitive control, offering a powerful, non-invasive approach to enhance brain function.
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #CognitiveHealth #Neurorehabilitation #VR
www.emjreviews.com/en-us/amj/ne...
#AMJNeurology #CognitiveHealth #Neurorehabilitation #VR
🧫 Nasal irrigation could replace sputum testing for infection monitoring in cystic fibrosis. The method accurately detects P. aeruginosa and S. aureus, offering a practical, non-invasive diagnostic tool.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #CysticFibrosis
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #CysticFibrosis
Nasal Irrigation Rivals Sputum Testing in Cystic Fibrosis
Nasal irrigation could serve as a reliable, less invasive alternative to sputum tests for detecting airway infections in cystic fibrosis, according to new diagnostic accuracy data.
www.emjreviews.com
October 23, 2025 at 11:24 AM
🧫 Nasal irrigation could replace sputum testing for infection monitoring in cystic fibrosis. The method accurately detects P. aeruginosa and S. aureus, offering a practical, non-invasive diagnostic tool.
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #CysticFibrosis
www.emjreviews.com/en-us/amj/re...
#AMJRespiratory #CysticFibrosis
💪 New research reveals that people with psoriatic arthritis have markedly reduced cardiorespiratory fitness versus healthy controls, underscoring the need for early lifestyle interventions to improve long-term health outcomes.
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
Psoriatic Arthritis Shows Lower Cardiorespiratory Fitness Levels
Cross-sectional testing shows reduced cardiorespiratory fitness in psoriatic arthritis, with disease activity and adiposity linked to lower VO2peak and self-reported activity linked to higher fitness.
www.emjreviews.com
October 22, 2025 at 4:58 PM
💪 New research reveals that people with psoriatic arthritis have markedly reduced cardiorespiratory fitness versus healthy controls, underscoring the need for early lifestyle interventions to improve long-term health outcomes.
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
www.emjreviews.com/en-us/amj/rh...
#AMJRheumatology #AutoimmuneDisease
💉 New data show a single RSV vaccine dose reduced severe illness by almost 80% and lowered hospitalization rates in adults aged 60+. Strong evidence that vaccination offers vital protection for older adults this winter.
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #InfectiousDiseases
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #InfectiousDiseases
RSV Vaccine Cuts Severe Illness in Seniors
First postlicensure season data show high RSV vaccine effectiveness against acute respiratory illness in older adults, including high-risk subgroups and severe outcomes, supporting broad uptake in eli...
www.emjreviews.com
October 22, 2025 at 3:20 PM
💉 New data show a single RSV vaccine dose reduced severe illness by almost 80% and lowered hospitalization rates in adults aged 60+. Strong evidence that vaccination offers vital protection for older adults this winter.
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #InfectiousDiseases
www.emjreviews.com/en-us/amj/mi...
#AMJMicrobiology #InfectiousDiseases
🧴 Skincare knowledge matters, people who understand proper skincare routines show milder acne and better self-care habits, according to new findings that spotlight education’s role in acne management.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #Acne #SkinHealth
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #Acne #SkinHealth
Skincare Awareness Linked with Milder Acne
In a cross-sectional study of 450 patients with acne, routine skincare use and higher education correlated with milder disease severity and fewer severe cases, underscoring counseling at every visit.
www.emjreviews.com
October 22, 2025 at 1:11 PM
🧴 Skincare knowledge matters, people who understand proper skincare routines show milder acne and better self-care habits, according to new findings that spotlight education’s role in acne management.
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #Acne #SkinHealth
www.emjreviews.com/en-us/amj/de...
#AMJDermatology #Acne #SkinHealth