MathieuSchulz
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msclz.bsky.social
MathieuSchulz
@msclz.bsky.social
Epigenetic, fertility, molecular biologist. Currently postdoc with Sarah Kimmins, previously PhD student with Deborah Bourc'his | rock & cat lover 🤘🐈 | Tpyos are my own.
Reposted by MathieuSchulz
It is with infinite sadness that we learned of the passing of Clarisse Orniacki.

She joined @vdoye.bsky.social lab and defended her thesis in December 2022 and pursued her career with a postdoc in‬ @tedfon.bsky.social at McGill University in Montreal .

Tribute 🔗 www.ijm.fr/tribute-to-c...
August 4, 2025 at 10:28 AM
Reposted by MathieuSchulz
Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data

by @erikvannimwegen.bsky.social and colleagues:

www.biorxiv.org/content/10.1...
Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data
Single-cell omics methods promise to revolutionize our understanding of gene regulatory processes during cell differentiation, but analysis of such data continues to pose a major challenge. Apart from...
www.biorxiv.org
May 9, 2025 at 11:08 AM
Reposted by MathieuSchulz
If you mutate 25 genes, you can make a Squire Wolf
April 9, 2025 at 1:06 PM
Reposted by MathieuSchulz
What's happening in the USA 🇺🇸 is terrifying and for European 🇪🇺 scientists this should be a wake up call. Here are my emotional rollercoaster🎢 and my 2 cents 💶. #standupforscience
March 20, 2025 at 9:00 AM
Reposted by MathieuSchulz
Hello, Bluesky! ☀️

We fund frontier research in Europe—bold ideas, unexpected discoveries and science that shapes the future. So it’s only fitting we’ve landed here. Sorry for being late.

Follow us for updates on ERC funding, research policy, and our grantees' discoveries.
February 7, 2025 at 8:16 AM
Reposted by MathieuSchulz
January 29, 2025 at 3:52 PM
It’s so exciting to see more and more scientific agencies and institutions joining 🦋

I feel like this is exactly what was missing on other platforms. In my opinion, it will definitely help strengthen the scientific community here! 💪🧬
January 27, 2025 at 10:33 PM
Reposted by MathieuSchulz
If you missed our most recent seminar with Drs. Sarah Kimmins and Mathieu Schulz, you can now find it online!

youtu.be/-CJNhM-1JhA

All of our other seminars can be found at thisisepigenetics.ca/events/semin...
Sperm epigenome in the transmission of disease from fathers to children (January 17, 2025)
YouTube video by CEEHRC VideoCast
youtu.be
January 27, 2025 at 2:38 PM
Reposted by MathieuSchulz
We kick off 2025 with our seminar series on Friday, January 17 at 12pm ET!

We have the pleasure of hosting Drs. Sarah Kimmins and Mathieu Schulz @msclz.bsky.social where they will discuss the role of the sperm epigenome in development.

Register at:
us06web.zoom.us/webinar/regi...
Welcome! You are invited to join a webinar: CEEHRC January 17th 2025 - Kimmins. After registering, you will receive a confirmation email about joining the webinar.
The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network is a network run by epigenetic researchers from across Canada, funded by the Canadian Institutes of Health Researc...
us06web.zoom.us
January 9, 2025 at 12:16 AM
Reposted by MathieuSchulz
www.biorxiv.org/content/10.1...
Our study published today on #bioRxiv describe the identification of a deaminase that converts 5mC to T, enabling direct sequencing of the human methylome and genome. This achievement was made possible through a collaborative effort across all departments at #NEB.
December 9, 2024 at 2:12 PM
Reposted by MathieuSchulz
Happy to share our preprint👇
Congrats and thanks to all the co-authors 🙏
📢 Preprint! How does the environment of a father before conception influence offspring?

Even more, how do paternal genetics & ages interact with exposures to affect F1 outcome?

We tested this systematically, with intriguing findings & some cautionary tales🧵...

www.biorxiv.org/content/10.1...
Embryonic Signatures of Intergenerational Inheritance across Paternal Environments and Genetic Backgrounds
The paternal preconception environment has been implicated as a modulator of phenotypic traits and disease risk in F1 offspring. However, the prevalence and mechanisms of such intergenerational epigen...
www.biorxiv.org
November 27, 2024 at 9:01 AM
Reposted by MathieuSchulz
(1st post @BlueSky) Preprint alert🚨a long thread. Cautions in the use of @nanopore sequencing to map DNA modifications: officially reported “accuracy” ≠ reliable mapping in real applications. We performed a critical assessment of nanopore sequencing (across different versions of models) for the 1/n
November 20, 2024 at 11:41 AM
Reposted by MathieuSchulz
SOX and POU are crucial Transcription Factors in animal development, believed to be innovations of this group. Here we find them in unicellular relatives of animals. And hold tight, you can use a choanoflagellate 🦠 SOX gene to make a full chimeric 🐁 ! Read more here 🧵: rdcu.be/d0dPN 1/6
The emergence of Sox and POU transcription factors predates the origins of animal stem cells
Nature Communications - The pluripotency program is maintained by transcription factors from the Sox and POU families. Here they identify SOX and POU factors from unicellular relatives of animals...
rdcu.be
November 14, 2024 at 5:15 PM
Reposted by MathieuSchulz
I've been meaning to write a lengthy thread about our experiences with DNA methylation editing in mouse ESCs if that would be useful (or interesting?) for a niche audience here. tl;dr: it was frustrating but we learned a lot, and it ended with our shiny new pub (1/17) www.nature.com/articles/s41...
November 12, 2024 at 9:38 PM