Theodore Morley
@morleytheodore.bsky.social
Researcher in the Center for Digital Genomic Medicine and Ruderfer Lab at Vanderbilt University Medical Center. I do ML research in genetics and healthcare! Views my own.
Truly the way that extremely important guidelines should be decided, huh. Just based on what some guy with no qualifications feels like it should be. Vibes based medical policy.
Trump: "The MMR I think should be taken separately. This is based on what I feel."
September 22, 2025 at 11:22 PM
Truly the way that extremely important guidelines should be decided, huh. Just based on what some guy with no qualifications feels like it should be. Vibes based medical policy.
Reposted by Theodore Morley
Stuttering is the most common speech fluency disorder and is as heritable as many common complex traits. Yet, genetic research of stuttering has lagged behind other human traits. In collaboration with #23andme we conducted the first large-scale GWAS of stuttering. www.nature.com/articles/s41...
Large-scale genome-wide analyses of stuttering - Nature Genetics
Genome-wide analyses in over one million self-reported cases and controls identify genetic variants associated with stuttering and find genetic correlations with autism, depression and impaired musica...
www.nature.com
July 28, 2025 at 10:52 AM
Stuttering is the most common speech fluency disorder and is as heritable as many common complex traits. Yet, genetic research of stuttering has lagged behind other human traits. In collaboration with #23andme we conducted the first large-scale GWAS of stuttering. www.nature.com/articles/s41...
Reposted by Theodore Morley
I don't think anyone outside of universities, pharma and biotech, independent research institutions have any idea of what is happening right now. If you haven't sounded the alarm among your friends, family and colleagues, now is the time to do it.
May 31, 2025 at 11:25 AM
I don't think anyone outside of universities, pharma and biotech, independent research institutions have any idea of what is happening right now. If you haven't sounded the alarm among your friends, family and colleagues, now is the time to do it.
Reposted by Theodore Morley
How bad will it be? Catastrophic.
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
May 31, 2025 at 2:50 AM
Reposted by Theodore Morley
This is the missing thing. If you touch real data or real problems enough, it's hard to fool yourself
This is why I like (in my ML for climate change work) partnering with people with real data needs. You know what you're doing matters and you know if you're getting it right.
May 19, 2025 at 8:33 PM
This is the missing thing. If you touch real data or real problems enough, it's hard to fool yourself
Flying to #Canada for summer vacation this year to go back and visit friends in Montreal (flying out of Nashville), and the price difference between flying now and a few months ago is stark. Canadians are certainly not flying to the US lately, for obvious reasons. That boycott is definitely hittin.
May 19, 2025 at 6:54 PM
Flying to #Canada for summer vacation this year to go back and visit friends in Montreal (flying out of Nashville), and the price difference between flying now and a few months ago is stark. Canadians are certainly not flying to the US lately, for obvious reasons. That boycott is definitely hittin.
Objectively a really funny statement to make about a feature that you literally can't opt out of, which is forced to the top of the search results for the most market-dominant search engine on the planet.
ALPHABET CEO - AI OVERVIEWS NOW HAS MORE THAN 1.5 BLN USERS EVERY MONTH, NEARLY A YEAR AFTER U.S. LAUNCH - CONF. CALL
April 24, 2025 at 9:05 PM
Objectively a really funny statement to make about a feature that you literally can't opt out of, which is forced to the top of the search results for the most market-dominant search engine on the planet.
This proposal is a disaster.
It's mind boggling how much this, alongside existing cuts, will irreparably slow the scientific progress of the human race, harm our children's education, and damage our health as a society.
It's mind boggling how much this, alongside existing cuts, will irreparably slow the scientific progress of the human race, harm our children's education, and damage our health as a society.
New: A 64-page HHS restructuring proposal outlines sweeping cuts to US public health.
Here it is, in its entirety.
open.substack.com/pub/insideme...
Here it is, in its entirety.
open.substack.com/pub/insideme...
New: A 64-page HHS restructuring proposal outlines sweeping cuts to US public health. Here it is, in its entirety.
Inside Medicine is made possible entirely by reader upgrades.
open.substack.com
April 17, 2025 at 7:50 PM
This proposal is a disaster.
It's mind boggling how much this, alongside existing cuts, will irreparably slow the scientific progress of the human race, harm our children's education, and damage our health as a society.
It's mind boggling how much this, alongside existing cuts, will irreparably slow the scientific progress of the human race, harm our children's education, and damage our health as a society.
Very well attended town hall for @warren.senate.gov in Nashville Tennessee! It's great to see Democrats holding a real town hall in Tennessee to pick up the slack as the Republicans ignore all their constituents.
April 5, 2025 at 8:02 PM
Very well attended town hall for @warren.senate.gov in Nashville Tennessee! It's great to see Democrats holding a real town hall in Tennessee to pick up the slack as the Republicans ignore all their constituents.
Huge crowd to protest today in Nashville! #HandsOff2025
April 5, 2025 at 7:34 PM
Huge crowd to protest today in Nashville! #HandsOff2025
I've been thinking of giving some blogging a try, so I wrote about an interesting phenomenon I've noticed over the years of tech workers often fantasizing about quitting their jobs to start a farm or a crafts-based job: tjmorley.com/blogposts/co...
Cottagecore Programmers: The Idealization of Farming by Tech
tjmorley.com
March 24, 2025 at 5:31 PM
I've been thinking of giving some blogging a try, so I wrote about an interesting phenomenon I've noticed over the years of tech workers often fantasizing about quitting their jobs to start a farm or a crafts-based job: tjmorley.com/blogposts/co...
Reposted by Theodore Morley
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
March 18, 2025 at 11:27 PM
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
Reposted by Theodore Morley
Here's a quantitative illustration of what's happening with NIH funding.
February 12, 2025 at 6:58 PM
Here's a quantitative illustration of what's happening with NIH funding.
Great crowd today standing up for science in Nashville, TN! About 300 people I believe, lots of great signs and passionate citizens!
March 7, 2025 at 10:00 PM
Great crowd today standing up for science in Nashville, TN! About 300 people I believe, lots of great signs and passionate citizens!
Reposted by Theodore Morley
About 300 people are outside the Capitol in Nashville for the Stand Up For Science rally. Similar demonstrations are happening across the country. Here are their policy goals: standupforscience2025.org/our-policy-g...
March 7, 2025 at 8:21 PM
About 300 people are outside the Capitol in Nashville for the Stand Up For Science rally. Similar demonstrations are happening across the country. Here are their policy goals: standupforscience2025.org/our-policy-g...
Reposted by Theodore Morley
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
March 6, 2025 at 7:14 PM
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
Reposted by Theodore Morley
"In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet 'agency priorities'"
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
www.nature.com
March 6, 2025 at 3:08 AM
"In an unprecedented move, the US National Institutes of Health (NIH) has begun mass terminations of research grants that fund active scientific projects because they no longer meet 'agency priorities'"
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Wherever I go in life, I am proud to be a Vermonter.
Hundreds of protesters gathered in Waitsfield on Saturday morning to protest Vice President JD Vance, who is visiting Vermont with his family for a ski trip this weekend.
March 2, 2025 at 3:09 AM
Wherever I go in life, I am proud to be a Vermonter.
Reposted by Theodore Morley
Study finds incorporating PRS into clinical prediction models provides limited improvements in performance bit.ly/3EUjUJT #machinelearning #genomicmedicine #EHR
February 25, 2025 at 9:26 PM
Study finds incorporating PRS into clinical prediction models provides limited improvements in performance bit.ly/3EUjUJT #machinelearning #genomicmedicine #EHR
Glad to announce that our paper examining the varying methods for combining genetic information with EHR-based features in prediction is now fully out in Genetics in Medicine: doi.org/10.1016/j.gi...
I'll write some more details in the comments below!
I'll write some more details in the comments below!
Redirecting
doi.org
February 25, 2025 at 5:00 PM
Glad to announce that our paper examining the varying methods for combining genetic information with EHR-based features in prediction is now fully out in Genetics in Medicine: doi.org/10.1016/j.gi...
I'll write some more details in the comments below!
I'll write some more details in the comments below!
Roasted up some duck a l'orange, fingerling potatoes, and made some mochi from scratch for dessert as a Christmas dinner for my wife and myself.
Tomorrow it's back to work setting up an RCT, but today is a day to relax. I hope everyone enjoys their holidays and spending time with their loved ones!
Tomorrow it's back to work setting up an RCT, but today is a day to relax. I hope everyone enjoys their holidays and spending time with their loved ones!
December 26, 2024 at 2:16 AM
Roasted up some duck a l'orange, fingerling potatoes, and made some mochi from scratch for dessert as a Christmas dinner for my wife and myself.
Tomorrow it's back to work setting up an RCT, but today is a day to relax. I hope everyone enjoys their holidays and spending time with their loved ones!
Tomorrow it's back to work setting up an RCT, but today is a day to relax. I hope everyone enjoys their holidays and spending time with their loved ones!
I feel like I should post something on here but don't have anything science related I want to post right at this moment, so here's a picture I took while hiking in Colorado after AGBT Precision Health a little while ago!
November 14, 2024 at 4:55 AM
I feel like I should post something on here but don't have anything science related I want to post right at this moment, so here's a picture I took while hiking in Colorado after AGBT Precision Health a little while ago!
Hello world, figured I'd check out this app to see how it is since I saw a few people moving over!
November 1, 2024 at 1:53 AM
Hello world, figured I'd check out this app to see how it is since I saw a few people moving over!