Mohammad Iyas Kawas
@moekawas.bsky.social
Post-Doctoral Researcher, Neuroscience, fMRI, Alzheimer's Disease. Father, Husband, and cooking enthusiast
Reposted by Mohammad Iyas Kawas
Excited to share our work making an "allostasis-first" case that brain function is most productively framed in terms of its core regulatory function. We also introduce some new ideas in the context of metabolism and cognitive function in Alzheimer's.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
October 14, 2025 at 7:56 PM
Excited to share our work making an "allostasis-first" case that brain function is most productively framed in terms of its core regulatory function. We also introduce some new ideas in the context of metabolism and cognitive function in Alzheimer's.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Reposted by Mohammad Iyas Kawas
@benhayden.bsky.social
@tyrellturing.bsky.social
@jmgrohneuro.bsky.social
@pessoabrain.bsky.social
I see a lot of talk on here about how we should avoid
"x does y" talk because the brain is "a dynamic, reverberant, reciprocally interconnected system".
But this does not follow.
A thread...
@tyrellturing.bsky.social
@jmgrohneuro.bsky.social
@pessoabrain.bsky.social
I see a lot of talk on here about how we should avoid
"x does y" talk because the brain is "a dynamic, reverberant, reciprocally interconnected system".
But this does not follow.
A thread...
September 5, 2025 at 9:57 PM
@benhayden.bsky.social
@tyrellturing.bsky.social
@jmgrohneuro.bsky.social
@pessoabrain.bsky.social
I see a lot of talk on here about how we should avoid
"x does y" talk because the brain is "a dynamic, reverberant, reciprocally interconnected system".
But this does not follow.
A thread...
@tyrellturing.bsky.social
@jmgrohneuro.bsky.social
@pessoabrain.bsky.social
I see a lot of talk on here about how we should avoid
"x does y" talk because the brain is "a dynamic, reverberant, reciprocally interconnected system".
But this does not follow.
A thread...
Reposted by Mohammad Iyas Kawas
Precision Functional Mapping (PFM). 8 yrs ago some told us it wasn't interesting. Now it's helping cure depression as part of PACE (Personalized Adaptive Cortical Electro-stimulation), ... commercialized by @turingmedical.bsky.social.
osf.io/preprints/ps...
www.cell.com/neuron/comme...
osf.io/preprints/ps...
www.cell.com/neuron/comme...
August 12, 2025 at 1:54 AM
Precision Functional Mapping (PFM). 8 yrs ago some told us it wasn't interesting. Now it's helping cure depression as part of PACE (Personalized Adaptive Cortical Electro-stimulation), ... commercialized by @turingmedical.bsky.social.
osf.io/preprints/ps...
www.cell.com/neuron/comme...
osf.io/preprints/ps...
www.cell.com/neuron/comme...
Reposted by Mohammad Iyas Kawas
This is the future. The reality of biological #psychiatry. We listen to the patient, create a personalized map of their brain, use algorithms to disrupt stuck networks, and adapt the stimulation over time while continuing our quest to understand those networks.
Now with PFM, prior cortical stim work by @ziad-nahas.bsky.social for depression could be patient specific.
We developed the end-to-end minimally invasive PACE used by @drdaviddarrow.bsky.social to place electrodes directly on Mike's salience, default, fronto-parietal, and action mode networks.
We developed the end-to-end minimally invasive PACE used by @drdaviddarrow.bsky.social to place electrodes directly on Mike's salience, default, fronto-parietal, and action mode networks.
August 10, 2025 at 10:00 PM
This is the future. The reality of biological #psychiatry. We listen to the patient, create a personalized map of their brain, use algorithms to disrupt stuck networks, and adapt the stimulation over time while continuing our quest to understand those networks.
Reposted by Mohammad Iyas Kawas
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
Reposted by Mohammad Iyas Kawas
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
July 10, 2025 at 7:52 PM
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
Reposted by Mohammad Iyas Kawas
Alert!!!!
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
June 26, 2025 at 1:29 PM
Alert!!!!
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
“An Action Networks Model for Pain”
We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.
👉 thread below 🧵
osf.io/preprints/ps...
Reposted by Mohammad Iyas Kawas
Normality bias - ‘the tendency to underestimate the likelihood or impact of a potential hazard, based on the belief that things will continue as they have in the past’ - is a very hard habit to break.
March 1, 2025 at 9:35 AM
Normality bias - ‘the tendency to underestimate the likelihood or impact of a potential hazard, based on the belief that things will continue as they have in the past’ - is a very hard habit to break.