Mike in Cleveland
mikeincleveland.bsky.social
Mike in Cleveland
@mikeincleveland.bsky.social
A Florida Man in Cleveland. I like riding my bike, playing with my kids, and science (occasionally).
Reposted by Mike in Cleveland
EPSTEIN BOMBSHELL: my staff is releasing a new report showing JPMorgan Chase executives – all the way to the top – enabled Epstein's sex trafficking operation. You're going to want to read this.
Wyden Presses for Investigation Into JPMorgan Chase and Epstein
www.nytimes.com
November 20, 2025 at 3:26 PM
Reposted by Mike in Cleveland
This is another 10,000 word opus - I break down the entirety of OpenAI's finances, and explain that they're just another boring AI startup trying to build products on top of their models.

Sora 2 is a mirage - an unsustainable marketing tool.

Anyway, subscribe at the discount link below.
October 3, 2025 at 1:16 AM
Reposted by Mike in Cleveland
Several anti-ICE protestors on the Ohio-Kentucky border.

This is how the police dealt with them.

Literally beat the hell out of them.

This is Trump's police state America, coming to a protest near you.
September 5, 2025 at 2:32 AM
Reposted by Mike in Cleveland
(mf doom voice) he threw a sandwich cheese and salami, feds couldn't indict folded like origami, afraid of subway both the chain and the train, mayo salt and pepper shake your thang, grand jury shut em down twice, coca cola on the side no ice
August 27, 2025 at 8:44 PM
The pacing for UFC 318 is dogshit. It's midnight, and they're just starting the sizzle reel for the co-main. #ufc318
July 20, 2025 at 3:55 AM
Reposted by Mike in Cleveland
Weedkiller ingredient widely used in US can damage organs and gut bacteria, research shows. Diquat is banned in the UK, EU, China and other countries, but the US has resisted calls to regulate it. www.theguardian.com/environment/... via @us.theguardian.com
Weedkiller ingredient widely used in US can damage organs and gut bacteria, research shows
Diquat is banned in the UK, EU, China and other countries. The US has resisted calls to regulate it
www.theguardian.com
July 6, 2025 at 10:39 PM
Reposted by Mike in Cleveland
14/
Key takeaways:
High-dim data creates false signals

Multiple corrections aren’t optional

Simpler is safer

Always validate

Replication is king
May 26, 2025 at 1:15 PM
Am I the only one who was bothered by the bathroom opening outward in the wrong direction, allowing Milchick to get blocked in? You can see once he gets out, that the door opens inward like it actually should. #Severance
March 21, 2025 at 10:20 PM
Reposted by Mike in Cleveland
new track on our great lake greatest hits album 🔊
March 21, 2025 at 1:08 PM
Reposted by Mike in Cleveland
Mine in today’s @newyorker.com
March 12, 2025 at 2:46 PM
Reposted by Mike in Cleveland
An interesting data point worth exploring. 20 bucks a year. That’s it. That’s a couple Dunkin Donuts coffees. Seems like heck of an investment. To save an allied nation. Against a sworn enemy of the U.S….And the American people allegedly have “war fatigue?” Really? Weak sauce.
All military aid from the U.S. to Ukraine from 2014-2024 has cost the U.S. tax payer $19.94 per person per year.

In return they got to destroy Russia’s entire Soviet equipment inheritance and still complain it is a bad deal
March 9, 2025 at 4:48 AM
Reposted by Mike in Cleveland
Reposted by Mike in Cleveland
The current landscape and emerging challenges of benchmarking single-cell methods www.biorxiv.org/content/10....
February 22, 2025 at 2:45 PM
Reposted by Mike in Cleveland
I see amazing bravery, generosity, and leadership from folks illegally fired NIH and NSF jobs.

Then we have toadies doing what Jeremy highlights.

Yes. Sex is a biological variable. Gene expression, and endocrine environment, and reproductive physiology, and fuck why do I even have to type this?
From NIH Office of Research on Women's Health webpage

Sex as a Biological Variable tab

"Historic document published prior to January 20, 2025"

It looks like we are headed back to the good old days when women were consider to be small men for the purposes of research...
February 20, 2025 at 5:40 AM
Reposted by Mike in Cleveland
"I can’t tell you what the market is going to say, because I don’t know how quickly it’s able to assimilate reality....Because the reality is that tariffs are the least of our problems."

Monday's Triad from JVL out now: www.thebulwark.com/p/follow-the...
February 3, 2025 at 4:12 AM
Reposted by Mike in Cleveland
Quite the indictment of AI products: they are more appealing to people who don't understand how they work and see them as magical

The paper concludes: "businesses may benefit from targeting those with lower AI literacy" and "maintaining an aura of magic around AI" ✨

tinyurl.com/ynefd8zk
January 26, 2025 at 9:09 PM
Reposted by Mike in Cleveland
Certainly all the people who were up in arms about Biden not visiting North Carolina immediately will criticize the president’s “fuck you not my problem” attitude to disasters now
Trump: "We're looking at the whole concept of FEMA. I like, frankly, the concept when North Carolina gets hit, the governor takes care of it. When Florida gets hit, the governor takes care of it. Meaning the state takes care of it ... I'd like to see the states take care of disasters."
January 24, 2025 at 6:06 PM
Reposted by Mike in Cleveland
Every year I wait for a truly revolutionary piece of tech coming from CES and every year it's just "this $5,000 bidet now has a RBG strip lighting around the rim of the seat and for $25.99 a month you can buy a subscription to AI module that allows you to customize the colors."
January 13, 2025 at 2:12 PM
The amount of people on the site who hate fireworks on NYE is genuinely astounding. It's one night people, you're fine, I promise.
January 1, 2025 at 5:42 PM
Reposted by Mike in Cleveland
People sometimes make fun of science that sounds stupid and random.

Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea
Breaking News: The FDA approved use of the weight loss drug Zepbound for a common form of sleep apnea. It is the first drug authorized to treat the disorder.
F.D.A. Approves Weight-Loss Drug to Treat Sleep Apnea
Zepbound is the first prescription drug approved specifically to treat the common condition.
www.nytimes.com
December 21, 2024 at 12:41 AM
Reposted by Mike in Cleveland

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨
We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research!
Read more: bmcgenomics.biomedcentral.com/articles/10....
1/8
High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics
The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...
bmcgenomics.biomedcentral.com
December 3, 2024 at 8:38 AM
Reposted by Mike in Cleveland
New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇
November 28, 2024 at 7:07 PM