Michael Marty
@michaelmarty.bsky.social
Scientist, Mass Spec, Membrane Biochemistry, Lipids, Department of Chemistry, University of Texas at Austin, #Nanodiscs, #UniDec
To everyone doing cool data analysis stuff, I'd love to see some analytical chem applicants in this search! Please pass along.
We invite applications for tenure-track faculty whose research programs broadly align with the themes of Artificial Intelligence and Data Analytics (AI+DA) in the areas of life sciences, bioorganic, synthesis, analytical, materials, and generative AI.
apply.interfolio.com/174602
apply.interfolio.com/174602
Apply - Interfolio
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apply.interfolio.com
September 26, 2025 at 5:46 PM
To everyone doing cool data analysis stuff, I'd love to see some analytical chem applicants in this search! Please pass along.
Reposted by Michael Marty
We invite applications for tenured faculty in any area of experimental physical chemistry.
apply.interfolio.com/174607
apply.interfolio.com/174607
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 26, 2025 at 5:12 PM
We invite applications for tenured faculty in any area of experimental physical chemistry.
apply.interfolio.com/174607
apply.interfolio.com/174607
Assuming the voltages are correct, has anyone ever had issues running a 15 A mass spectrometer on a 30 A circuit?
August 6, 2025 at 7:45 PM
Assuming the voltages are correct, has anyone ever had issues running a 15 A mass spectrometer on a 30 A circuit?
We've got a new MassSpecCodingClub module posted. The videos are linked here: github.com/michaelmarty...
This module teaches how to parse FASTA files and read/write Pandas DataFrames. We explore an application of converting DDA data into an MRM transition list. Enjoy!
This module teaches how to parse FASTA files and read/write Pandas DataFrames. We explore an application of converting DDA data into an MRM transition list. Enjoy!
GitHub - michaelmarty/MassSpecCodingClub: A community dedicated to education of computer coding applied to mass spectrometry applications.
A community dedicated to education of computer coding applied to mass spectrometry applications. - GitHub - michaelmarty/MassSpecCodingClub: A community dedicated to education of computer coding a...
github.com
July 18, 2025 at 3:49 PM
We've got a new MassSpecCodingClub module posted. The videos are linked here: github.com/michaelmarty...
This module teaches how to parse FASTA files and read/write Pandas DataFrames. We explore an application of converting DDA data into an MRM transition list. Enjoy!
This module teaches how to parse FASTA files and read/write Pandas DataFrames. We explore an application of converting DDA data into an MRM transition list. Enjoy!
Anyone know of a nitrogen pressure booster that can bring the pressure up from ~90 psi to ~110 psi?
June 27, 2025 at 3:50 PM
Anyone know of a nitrogen pressure booster that can bring the pressure up from ~90 psi to ~110 psi?
New review article from Hiruni and Farhana on MS of membrane proteins in the context of biotherapeutics: doi.org/10.1002/9781...
(Preprint link here: doi.org/10.26434/che...)
(Preprint link here: doi.org/10.26434/che...)
Membrane Proteins: Challenging Biotherapeutic Targets
Membrane proteins are about 30% of the human proteome and serve important physiological roles, including chemical transport, cell signaling, and energy transduction. Consequently, they represent abou...
doi.org
June 12, 2025 at 2:01 PM
New review article from Hiruni and Farhana on MS of membrane proteins in the context of biotherapeutics: doi.org/10.1002/9781...
(Preprint link here: doi.org/10.26434/che...)
(Preprint link here: doi.org/10.26434/che...)
Reposted by Michael Marty
A Fast Neural Network for Isotopic Charge State Assignment #JACS pubs.acs.org/doi/10.1021/...
A Fast Neural Network for Isotopic Charge State Assignment
Electrospray ionization (ESI) mass spectrometry is an essential technique for chemical analysis in a range of fields. In ESI, analytes can produce multiple charge states, which must be correctly assig...
pubs.acs.org
June 10, 2025 at 8:01 PM
A Fast Neural Network for Isotopic Charge State Assignment #JACS pubs.acs.org/doi/10.1021/...
Excited to have this published in @jacs.acspublications.org! IsoDec is a new neural network for charge state assignment with high-resolution MS data. We test it for top-down proteomics. It's free and fast, what else could you want?
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
A Fast Neural Network for Isotopic Charge State Assignment
Electrospray ionization (ESI) mass spectrometry is an essential technique for chemical analysis in a range of fields. In ESI, analytes can produce multiple charge states, which must be correctly assig...
pubs.acs.org
June 10, 2025 at 5:41 PM
Excited to have this published in @jacs.acspublications.org! IsoDec is a new neural network for charge state assignment with high-resolution MS data. We test it for top-down proteomics. It's free and fast, what else could you want?
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Two new IsoDec tutorial videos to go over top-down proteomics searching with a few different workflows, one with TopPIC and the other with MetaMorpheus @metamorpheus.bsky.social :
youtu.be/OTQbplEezLQ
and
youtu.be/56OZJph48BU
youtu.be/OTQbplEezLQ
and
youtu.be/56OZJph48BU
IsoDec Tutorial 2: Analyzing LC-MS in the UniDec GUI with TopPIC search
YouTube video by Michael T Marty
youtu.be
May 14, 2025 at 7:43 PM
Two new IsoDec tutorial videos to go over top-down proteomics searching with a few different workflows, one with TopPIC and the other with MetaMorpheus @metamorpheus.bsky.social :
youtu.be/OTQbplEezLQ
and
youtu.be/56OZJph48BU
youtu.be/OTQbplEezLQ
and
youtu.be/56OZJph48BU
Reposted by Michael Marty
I am thrilled to share after years of work/procrastination that the MassQL manuscript is finally published in @natmethods.nature.com - "A universal language for finding mass spectrometry data patterns". This was an team effort from all co-authors that helped shape MassQL and how it could be used.
May 12, 2025 at 6:10 PM
I am thrilled to share after years of work/procrastination that the MassQL manuscript is finally published in @natmethods.nature.com - "A universal language for finding mass spectrometry data patterns". This was an team effort from all co-authors that helped shape MassQL and how it could be used.
Check out the latest tutorial video, from Marty Lab postdoc John Pavek, on how to analyze individual spectra with IsoDec, our new neural network for isotopic deconvolution: youtu.be/aOR37-j28NI
IsoDec Tutorial 1: Analysis of Individual Spectra
YouTube video by Michael T Marty
youtu.be
May 1, 2025 at 8:18 PM
Check out the latest tutorial video, from Marty Lab postdoc John Pavek, on how to analyze individual spectra with IsoDec, our new neural network for isotopic deconvolution: youtu.be/aOR37-j28NI
Would anyone be interested in me holding a UniDec/IsoDec office hour at ASMS this year?
March 24, 2025 at 5:16 PM
Would anyone be interested in me holding a UniDec/IsoDec office hour at ASMS this year?
Well, the USA may be getting worse, but UniDec is getting better. Check out the new version here: github.com/michaelmarty...
Mostly bug fixes. I'd love some people to try it out and let me know how it works on their computers. Hopefully it fixes issues with it getting blocked by antiviruses
Mostly bug fixes. I'd love some people to try it out and let me know how it works on their computers. Hopefully it fixes issues with it getting blocked by antiviruses
Release UniDec Version 8.0.1 · michaelmarty/UniDec
Version 8.0.1 UniDec.
Please cite Marty et al. Anal. Chem. 2015. DOI: 10.1021/acs.analchem.5b00140 if you use UniDec in publications.
Check out a video tutorial: https://www.youtube.com/watch?v=e33...
github.com
March 15, 2025 at 12:28 AM
Well, the USA may be getting worse, but UniDec is getting better. Check out the new version here: github.com/michaelmarty...
Mostly bug fixes. I'd love some people to try it out and let me know how it works on their computers. Hopefully it fixes issues with it getting blocked by antiviruses
Mostly bug fixes. I'd love some people to try it out and let me know how it works on their computers. Hopefully it fixes issues with it getting blocked by antiviruses
New paper from the group! Our first with MD simulations included. Congrats to Hiruni and Farhana, who worked really hard on this!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Alanine Scanning to Define Membrane Protein–Lipid Interaction Sites Using Native Mass Spectrometry
Lipids surrounding membrane proteins interact with different sites on the protein with varying specificities, ranging from highly specific to weak interactions. These interactions can modulate the str...
pubs.acs.org
March 6, 2025 at 5:05 PM
New paper from the group! Our first with MD simulations included. Congrats to Hiruni and Farhana, who worked really hard on this!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
New preprint from the lab on IsoDec, our new neural net for isotopic charge state assignment:
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
A Fast Neural Network for Isotopic Charge State Assignment
Electrospray ionization (ESI) mass spectrometry is an essential technique for chemical analysis in a range of fields. In ESI, analytes can produce multiple charge states, which must be correctly assig...
chemrxiv.org
February 21, 2025 at 4:00 PM
New preprint from the lab on IsoDec, our new neural net for isotopic charge state assignment:
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Does anyone have recommendations for good lab moving companies?
February 21, 2025 at 2:52 PM
Does anyone have recommendations for good lab moving companies?
Very excited to share this commentary written by Chae, Daniel, and myself about navigating the postdoc experience. This started out of a discussion in a @femalesinms.bsky.social pod last year. Enjoy!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Navigating the Postdoc Experience
There are many reasons to consider postdoctoral research after completing a Ph.D. For those interested in academic careers at all levels, a postdoctoral research associate (PDRA) position is often req...
pubs.acs.org
February 20, 2025 at 5:28 PM
Very excited to share this commentary written by Chae, Daniel, and myself about navigating the postdoc experience. This started out of a discussion in a @femalesinms.bsky.social pod last year. Enjoy!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Michael Marty
The first @asms.org Winter Conference in Santa Fe is in progress. An intrepid group of skiers and snow boarders took to the slopes at #SkiSantaFe for some free afternoon fun!
#TeamMassSpec
#TeamMassSpec
January 26, 2025 at 3:26 PM
The first @asms.org Winter Conference in Santa Fe is in progress. An intrepid group of skiers and snow boarders took to the slopes at #SkiSantaFe for some free afternoon fun!
#TeamMassSpec
#TeamMassSpec
Really excited to release a beta version of UniDec 8.0!
The coolest feature is a new AI-based charge assignment for isotopic resolution data. It's performing a little better than Thrash/Xtract but way faster. Try out IsoDec if you are doing top-down!
github.com/michaelmarty...
The coolest feature is a new AI-based charge assignment for isotopic resolution data. It's performing a little better than Thrash/Xtract but way faster. Try out IsoDec if you are doing top-down!
github.com/michaelmarty...
Release UniDec Version 8.0.0 · michaelmarty/UniDec
Version 8.0.0 UniDec.
Please cite Marty et al. Anal. Chem. 2015. DOI: 10.1021/acs.analchem.5b00140 if you use UniDec in publications.
Check out a video tutorial: https://www.youtube.com/watch?v=e33...
github.com
December 27, 2024 at 10:19 PM
Really excited to release a beta version of UniDec 8.0!
The coolest feature is a new AI-based charge assignment for isotopic resolution data. It's performing a little better than Thrash/Xtract but way faster. Try out IsoDec if you are doing top-down!
github.com/michaelmarty...
The coolest feature is a new AI-based charge assignment for isotopic resolution data. It's performing a little better than Thrash/Xtract but way faster. Try out IsoDec if you are doing top-down!
github.com/michaelmarty...
It’s official! The Marty Lab will be moving to Austin this summer. Looking forward to the new adventure!
We are excited to announce that Michael Marty will join our department in 2025! @michaelmarty.bsky.social
chemistry.utexas.edu/news/announc...
chemistry.utexas.edu/news/announc...
Michael Marty Joining Department
news
chemistry.utexas.edu
December 19, 2024 at 9:03 PM
It’s official! The Marty Lab will be moving to Austin this summer. Looking forward to the new adventure!
New paper from the group combining separations with CD-MS using Hadamard transform multiplexing: pubs.acs.org/doi/full/10....
Coupling Online Size Exclusion Chromatography with Charge Detection-Mass Spectrometry Using Hadamard Transform Multiplexing
Charge detection mass spectrometry (CD-MS) is a powerful technique for the analysis of large, heterogeneous biomolecules. By directly measuring the charge states of individual ions, CD-MS can measure ...
pubs.acs.org
October 14, 2024 at 4:21 PM
New paper from the group combining separations with CD-MS using Hadamard transform multiplexing: pubs.acs.org/doi/full/10....
Reposted by Michael Marty
Coupling online size exclusion chromatography with charge detection-mass spectrometry using Hadamard transform multiplexing chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
September 25, 2024 at 9:00 AM
Coupling online size exclusion chromatography with charge detection-mass spectrometry using Hadamard transform multiplexing chemrxiv.org/engage/...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
New paper from the group describing UniChromCD for time-resolved CD-MS data, especially with fancy demultiplexing strategies! Great work Skippy and team!
pubs.acs.org/doi/full/10....
As always, the software is open-source and free
pubs.acs.org/doi/full/10....
As always, the software is open-source and free
UniChromCD for Demultiplexing Time-Resolved Charge Detection-Mass Spectrometry Data
Charge detection mass spectrometry (CD-MS) enables characterization of large, heterogeneous analytes through the analysis of individual ion signals. Because hundreds to thousands of scans must be acqu...
pubs.acs.org
September 3, 2024 at 3:52 PM
New paper from the group describing UniChromCD for time-resolved CD-MS data, especially with fancy demultiplexing strategies! Great work Skippy and team!
pubs.acs.org/doi/full/10....
As always, the software is open-source and free
pubs.acs.org/doi/full/10....
As always, the software is open-source and free
Reposted by Michael Marty
Combining Fourier Transform Ion Mobility with Charge Detection Mass
Spectrometry for the Analysis of Multimeric Protein Complexes chemrxiv.org/engage/...
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#proteomics #prot-preprint
Spectrometry for the Analysis of Multimeric Protein Complexes chemrxiv.org/engage/...
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#proteomics #prot-preprint
July 1, 2024 at 2:20 PM
Combining Fourier Transform Ion Mobility with Charge Detection Mass
Spectrometry for the Analysis of Multimeric Protein Complexes chemrxiv.org/engage/...
---
#proteomics #prot-preprint
Spectrometry for the Analysis of Multimeric Protein Complexes chemrxiv.org/engage/...
---
#proteomics #prot-preprint
Finally excited to share our recent paper in Anal. Chem. using mutant cycles and native MS to study lipid binding: pubs.acs.org/doi/full/10....
Congrats to Hiruni, Farhana, and Megan on their hard work! Looking forward to seeing what's coming next!
Congrats to Hiruni, Farhana, and Megan on their hard work! Looking forward to seeing what's coming next!
Simultaneous Native Mass Spectrometry Analysis of Single and Double Mutants To Probe Lipid Binding to Membrane Proteins
Lipids are critical modulators of membrane protein structure and function. However, it is challenging to investigate the thermodynamics of protein–lipid interactions because lipids can simultaneously ...
pubs.acs.org
June 11, 2024 at 3:31 PM
Finally excited to share our recent paper in Anal. Chem. using mutant cycles and native MS to study lipid binding: pubs.acs.org/doi/full/10....
Congrats to Hiruni, Farhana, and Megan on their hard work! Looking forward to seeing what's coming next!
Congrats to Hiruni, Farhana, and Megan on their hard work! Looking forward to seeing what's coming next!