Michael Marty
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michaelmarty.bsky.social
Michael Marty
@michaelmarty.bsky.social
Scientist, Mass Spec, Membrane Biochemistry, Lipids, Department of Chemistry, University of Texas at Austin, #Nanodiscs, #UniDec
Pass on congrats from me! How all is well there!
September 27, 2025 at 12:42 AM
In this case, we are in a temporary space that we can’t modify. Seems to me like the MS should also have its own breakers in that case. I’ve blown a fuse on the instrument from shorts in boards but I’ve never seen an MS trip a building circuit
August 11, 2025 at 1:07 PM
This is perfect!
June 30, 2025 at 1:43 PM
Awesome! Send me an email, and I'd be happy to meet up.
May 1, 2025 at 8:42 PM
If you want to try it out, IsoDec is bundled with UniDec, and there is a simple GUI for doing individual spectra and full files. For doing full top-down proteomics searches, we've bundled it into @metamorpheus.bsky.social, where it really shines!
February 21, 2025 at 4:00 PM
We ended up with something that worked pretty well, and John Pavek, a postdoc in the group, worked on getting it into a top-down proteomics workflow. It's not leaps and bounds beyond other tools, but it's a decent improvement that nicely balances speed, accuracy, and depth.
February 21, 2025 at 4:00 PM
For a long time, I've tried to get UniDec to work for isotopic data, but it never really panned out. After getting a grant from NSF to go after the problem, I spent the summer trying to train AI to assign isotopic cluster charge states.
February 21, 2025 at 4:00 PM