melbechon.bsky.social
@melbechon.bsky.social
Reposted
RBC cast containing several WBC's - brightfield with Prescott-Brodie stain - from new consult: admitted with SOB, nodular pulm infiltrate, and AKI - serologies pending. bx tomorrow ... #UrineMicroscopy #UrinarySediment
December 3, 2024 at 3:24 AM
Reposted
In the setting of these results across ckd, HF, and CV outcomes:

It’s still hard to ask a fixed income (eg medicare/medicaid) patient to switch from spiro to finerenone.

Easier when they have CKD and CV along with HF.

#MedSky #NephSky #CardioSky
#PatientsHealthFirst financial tox of health care
December 2, 2024 at 5:42 PM
Reposted
Diagnosis, management and treatment of the #Alport syndrome – 2024 #guideline on behalf of ERKNet, ERA and ESPN
#nephsky
academic.oup.com/ndt/advance-...
Diagnosis, management and treatment of the Alport syndrome – 2024 guideline on behalf of ERKNet, ERA and ESPN
Abstract. Glomerular nephropathy resulting from the genetic defects in COL4A3/4/5 genes including the classical Alport syndrome (AS) is the second commones
academic.oup.com
December 3, 2024 at 2:04 AM
Reposted
Also, given the recent TAPIR trial findings, when would you stop steroids, after tapering in a PR3 +ve AAV pt (with RPGN) who has just commenced Rituximab maintenance after initial induction Rx. #nephsky #rheumsky
bsky.app/profile/arvi...
In GPA after inductn, use of low-dose prednisone (5 mg/day) prevents more disease relapses over 6 mths than being fully off prednisone. The benefit of low-dose pred (5 mg/day) to prevent minor flares is seen only among pts treated with a non-rituximab-based regimen acrabstracts.org/abstract/a-m...
December 3, 2024 at 2:33 AM
Reposted
🆕🚨Heard of Dupilumab ?
It's new to #Nephrology

Dupilumab ➡️human monoclonal IgG4 Ab : inhibits IL-4 and IL-13 🛑

It's approved for atopic dermatitis !

Can be useful in cases with severe atopy & Membranous GN 🫘
@isnkidneycare

#NephTwitter #NephSky
#Medtwitter #NephEd
#Nephronuggets
December 3, 2024 at 10:33 AM
Reposted
diuretics, heart failure, loop diuretics, thiazides, sglt2i

'avoid premature cessation of diuretic therapy, doubling of creatinine or an increase greater than 1 mg/dL (instead of > 0.3 mg/dL) has been suggested as true renal dysfunction' #cardiosky #nephrosky #nephsky

www.ccjm.org/content/89/1...
How do we maximize diuresis in acute decompensated heart failure?
The initial goal is to maximize loop diuretic therapy using urine output or urinary sodium for guidance. Combination therapy can be used when patients respond poorly to escalating loop diuretic doses.
www.ccjm.org
December 3, 2024 at 10:56 AM