Marie-Charlotte
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mcallichon.bsky.social
Marie-Charlotte
@mcallichon.bsky.social
👩🏼, rider 🐎 and postdoc at @PittPsychiatry

PhD from Sorbonne University 🇫🇷🧠 into heteromers, addiction and depression
Reposted by Marie-Charlotte
"Untangling the multifaceted VTA responses to stress"
http://dlvr.it/TPKFpf

@dralexharris.bsky.social @ampolter.bsky.social & Urszula Skupio
@cp-trendsneuro.bsky.social
#SfN2025
November 17, 2025 at 11:16 PM
Reposted by Marie-Charlotte
Dopamine dynamics in the nucleus accumbens core reflected decision confidence during evaluation of decisions in an economic foraging task in mice, as well as both past and future value during re-evaluation and change-of-mind

@perothwell.bsky.social

www.nature.com/articles/s41...
Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind - Nature Neuroscience
Differences in neuroeconomic decision-making influence nucleus accumbens dopamine dynamics and reflect choice confidence during evaluation, as well as past and future value during re-evaluation, which...
www.nature.com
August 4, 2025 at 4:29 PM
Reposted by Marie-Charlotte
New paper alert!🚨📝

Paper: tinyurl.com/2cycsy6d
Press release: tinyurl.com/yur3j2n8

How the brain 🧠 engages in change-of-mind decisions taps into cognitive biases that depend on sensitivity to sunk costs & regret - both of which may contribute to negative rumination…however…🧵👇1/6 #ScienceAdvances
Change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex in a sex-dependent manner
Long non-coding RNA LINC00473 in mPFC alters change-of-mind re-evaluative decision-making behavior related to negative rumination.
tinyurl.com
July 15, 2025 at 1:43 AM
Reposted by Marie-Charlotte
Nicotine doesn’t just “turn on” the brain’s reward circuits — it reshapes them. Our new paper in Nature Communications shows that activating reward-linked dopamine neurons also sets off a feedback loop that drives negative emotional states.
www.nature.com/articles/s41...
Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety-like behaviors - Nature Communications
Drugs of abuse exert both motivational and emotional effects. Here, the authors show that nicotine and ethanol activate a VTA–NAc loop that inhibits dopamine neurons projecting to the amygdala, thereb...
www.nature.com
July 5, 2025 at 1:19 PM
Reposted by Marie-Charlotte
Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8
March 4, 2025 at 4:34 PM