Mark Wossidlo
@markwossidlo.bsky.social
Scientist, Partner, Dad, Adventurer.
Reposted by Mark Wossidlo
📢 New publication from the Vesely group in @jem.org!
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!
🧬 👉 rupress.org/jem/article/...
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!
🧬 👉 rupress.org/jem/article/...
Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis | Journal of Experimental Medicine | Rockefeller University Press
In this study, Gawish et al. show that RNA editing of the actin cross-linker FLNA is similarly regulated in mice and humans and that the targeted induction
rupress.org
June 8, 2025 at 6:13 AM
📢 New publication from the Vesely group in @jem.org!
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!
🧬 👉 rupress.org/jem/article/...
Led by Riem Gawish, this study shows that edited Filamin A in myeloid cells can protect mice from chemically induced colitis.
Congratulations to all involved in this exciting collaborative work!
🧬 👉 rupress.org/jem/article/...
Reposted by Mark Wossidlo
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 21, 2025 at 3:05 PM
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
Reposted by Mark Wossidlo
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
May 14, 2025 at 4:01 PM
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Reposted by Mark Wossidlo
This guy nails it
This is why basic (aka blue skies) research is so important. It’s fundamental to discoveries that change lives and improve humanity
This is why basic (aka blue skies) research is so important. It’s fundamental to discoveries that change lives and improve humanity
January 28, 2025 at 7:03 AM
This guy nails it
This is why basic (aka blue skies) research is so important. It’s fundamental to discoveries that change lives and improve humanity
This is why basic (aka blue skies) research is so important. It’s fundamental to discoveries that change lives and improve humanity
Reposted by Mark Wossidlo
2024 is coming to a close, and what a year it was for the GMI! As we recap this year’s highlights, let’s start with the biggest achievements by our Students and Postdocs in 2024.
December 5, 2024 at 11:13 AM
2024 is coming to a close, and what a year it was for the GMI! As we recap this year’s highlights, let’s start with the biggest achievements by our Students and Postdocs in 2024.
Reposted by Mark Wossidlo
By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12
Redirecting
doi.org
December 2, 2024 at 4:44 PM
By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12
Reposted by Mark Wossidlo
Let’s go! Less than two weeks to the 46th International Annual Asilomar #Chromatin, #Chromosomes, and #Epigenetics Conference Dec 12-15, 2024, in Pacific Grove, CA! asilomarchromatin.com #AsilomarChromatin
November 29, 2024 at 11:22 PM
Let’s go! Less than two weeks to the 46th International Annual Asilomar #Chromatin, #Chromosomes, and #Epigenetics Conference Dec 12-15, 2024, in Pacific Grove, CA! asilomarchromatin.com #AsilomarChromatin
Reposted by Mark Wossidlo
Our lab members are off to cool new jobs (including faculty 🎉) so we are looking for new team members. Experimental postdoc prioritized, but do get in touch if you think you are a good fit.
Also, our PhD program is currently accepting applications: www.molgen.mpg.de/IMPRS/applic...
Also, our PhD program is currently accepting applications: www.molgen.mpg.de/IMPRS/applic...
Application
The graduate program IMPRS for Biology And Computation (IMPRS-BAC) provides an education for students at the interface of molecular life sciences and computational sciences. This is based on perspective and supervision from both ends - experimental and computational - and suits students with degrees in molecular biology, biochemistry, mathematics, bioinformatics or any related areas. If you have a passion for epigenetics, bioinformatics, developmental biology, mathematics, sequence analysis, gene regulation, RNA biology, mechanobiology, protein biochemistry, stem cells and differentiation, statistics, molecular evolution or biophysics and want to work at the Max Planck Institute for Molecular Genetics or the Freie Universität Berlin - this is the program for you!
www.molgen.mpg.de
November 27, 2024 at 11:16 AM
Our lab members are off to cool new jobs (including faculty 🎉) so we are looking for new team members. Experimental postdoc prioritized, but do get in touch if you think you are a good fit.
Also, our PhD program is currently accepting applications: www.molgen.mpg.de/IMPRS/applic...
Also, our PhD program is currently accepting applications: www.molgen.mpg.de/IMPRS/applic...
Hello Bluesky! Excited to reconnect with a vibrant and healthy scientific community. Eager to explore #epigenetics and #DNAmethylation insights from the experts here!
November 22, 2024 at 6:57 PM
Hello Bluesky! Excited to reconnect with a vibrant and healthy scientific community. Eager to explore #epigenetics and #DNAmethylation insights from the experts here!