Mark C Turner
@markcturner.bsky.social
Assistant Professor in Endocrinology & Metabolism. Interested in skeletal muscle response to diet, exercise and pharmaceuticals.
Congratulations to Ryan Brett who successfully defended his PhD thesis today. It has been great to work with you and develop as a researcher. A big thank you to examiners Dr Mike Dodd and Prof Lee Roberts. Thank you to Derek Renshaw and Leanne Hodson for their support and guidance as supervisors.
August 11, 2025 at 8:43 PM
Congratulations to Ryan Brett who successfully defended his PhD thesis today. It has been great to work with you and develop as a researcher. A big thank you to examiners Dr Mike Dodd and Prof Lee Roberts. Thank you to Derek Renshaw and Leanne Hodson for their support and guidance as supervisors.
Reposted by Mark C Turner
Unraveling Skeletal Muscle Insulin Resistance: Molecular Mechanisms and the Restorative Role of Exercise
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Unraveling Skeletal Muscle Insulin Resistance: Molecular Mechanisms and the Restorative Role of Exercise | Circulation Research
Skeletal muscle is essential for movement and maintaining energy homeostasis and is
the primary tissue for insulin-stimulated glucose uptake. Skeletal muscle is composed
of various cell types that hel...
www.ahajournals.org
July 4, 2025 at 10:58 PM
Unraveling Skeletal Muscle Insulin Resistance: Molecular Mechanisms and the Restorative Role of Exercise
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Reposted by Mark C Turner
Excited to share our new work in PDAC Cachexia. This work demonstrated that addition of factors like advanced age in murine models can uncover signatures that might have been obscured in other models.
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Cachexia is a devastating cancer comorbidity that impacts numerous cancer outcomes. In @jem.org, @aneedasgupta.bsky.social, @jdoles.bsky.social et al describe a novel metabolic pathway/target w/ clinical implications for the treatment of cachectic #PancreaticCancer rupress.org/jem/article/...
July 2, 2025 at 4:49 PM
Excited to share our new work in PDAC Cachexia. This work demonstrated that addition of factors like advanced age in murine models can uncover signatures that might have been obscured in other models.
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Reposted by Mark C Turner
This study investigates possible off-target effects of the often-used antibiotic #streptomycin on myoblast cell function. Reduced global #protein #synthesis rate in differentiating #myotubes is reported, while #myoblast proliferation is unaffected.
doi.org/10.14814/phy...
#MyoBlue #CellPhysiology
doi.org/10.14814/phy...
#MyoBlue #CellPhysiology
doi.org
June 27, 2025 at 9:02 AM
This study investigates possible off-target effects of the often-used antibiotic #streptomycin on myoblast cell function. Reduced global #protein #synthesis rate in differentiating #myotubes is reported, while #myoblast proliferation is unaffected.
doi.org/10.14814/phy...
#MyoBlue #CellPhysiology
doi.org/10.14814/phy...
#MyoBlue #CellPhysiology
The skeletal muscle response to high‐intensity training assessed by single‐nucleus RNA‐sequencing is blunted in individuals with type 2 diabetes - Hansen - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.1113/...
The skeletal muscle response to high‐intensity training assessed by single‐nucleus RNA‐sequencing is blunted in individuals with type 2 diabetes
Abstract figure legend The figure illustrates the impact of high-intensity interval training (HIIT) on skeletal muscle metabolism and insulin sensitivity in individuals with type 2 diabetes and healt...
physoc.onlinelibrary.wiley.com
June 2, 2025 at 11:19 AM
The skeletal muscle response to high‐intensity training assessed by single‐nucleus RNA‐sequencing is blunted in individuals with type 2 diabetes - Hansen - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by Mark C Turner
Member Insights Webinar: Volunteerism | Join our team on Thursday, May 29 at 12:00 PM ET to learn how to grow your network, develop your leadership skills, and support the field of endocrinology through volunteering with the Endocrine Society. Register today: bit.ly/4c00O0W #endocrinology
May 20, 2025 at 7:51 PM
Member Insights Webinar: Volunteerism | Join our team on Thursday, May 29 at 12:00 PM ET to learn how to grow your network, develop your leadership skills, and support the field of endocrinology through volunteering with the Endocrine Society. Register today: bit.ly/4c00O0W #endocrinology
Reposted by Mark C Turner
Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains
portlandpress.com/biochemsoctr...
portlandpress.com/biochemsoctr...
Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains
Branched ubiquitin chains are complex molecular structures in which two or more ubiquitin moieties are attached to distinct lysine residues of a single ubiquitin molecule within a polyubiquitin chain....
portlandpress.com
May 18, 2025 at 9:03 AM
Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains
portlandpress.com/biochemsoctr...
portlandpress.com/biochemsoctr...
Reposted by Mark C Turner
If you would like to attend a #microscopy or #bioimageanalysis training course in the next 6 months but don’t have funding, check out our Microscopy Training Grant from @jcellsci.bsky.social and @focalplane.bsky.social.
Next deadline: 6 June 2025
www.biologists.com/grants/jcs-f...
#Training
Next deadline: 6 June 2025
www.biologists.com/grants/jcs-f...
#Training
May 13, 2025 at 8:46 AM
If you would like to attend a #microscopy or #bioimageanalysis training course in the next 6 months but don’t have funding, check out our Microscopy Training Grant from @jcellsci.bsky.social and @focalplane.bsky.social.
Next deadline: 6 June 2025
www.biologists.com/grants/jcs-f...
#Training
Next deadline: 6 June 2025
www.biologists.com/grants/jcs-f...
#Training
New publication from our research group in Coventry. Congratulations to Sharn and Jason on there hard work and the countless hours collecting the data and getting the publication out!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Adverse effects of high‐fat diet consumption on contractile mechanics of isolated mouse skeletal muscle are reduced when supplemented with resveratrol
Abstract figure legend An evaluation of the effectiveness of resveratrol as an anti-obesogenic nutritional strategy to mitigate the adverse effects of a high-fat diet on skeletal muscle health. Resve....
physoc.onlinelibrary.wiley.com
May 11, 2025 at 7:04 PM
New publication from our research group in Coventry. Congratulations to Sharn and Jason on there hard work and the countless hours collecting the data and getting the publication out!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by Mark C Turner
Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization
jbiomedsci.biomedcentral.com/articles/10....
jbiomedsci.biomedcentral.com/articles/10....
Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization - Journal of Biomedical Science
Background Skeletal muscle atrophy involves significant remodeling of fibers and is characterized by deficits in mitochondrial content and function. These changes are intimately connected to shifts in...
jbiomedsci.biomedcentral.com
February 21, 2025 at 10:26 PM
Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization
jbiomedsci.biomedcentral.com/articles/10....
jbiomedsci.biomedcentral.com/articles/10....
Reposted by Mark C Turner
Want to come work with us to understand the role of mitochondrial permeability transition in skeletal muscle? Postdoc position available at UF on the BREATHE T32 (US citizens and permanent residents eligible). breathe.phhp.ufl.edu/training/bre...
BREATHE Application » Breathing Research and Therapeutics Center » College of Public Health and Health Professions » University of Florida
.
breathe.phhp.ufl.edu
January 22, 2025 at 7:59 PM
Want to come work with us to understand the role of mitochondrial permeability transition in skeletal muscle? Postdoc position available at UF on the BREATHE T32 (US citizens and permanent residents eligible). breathe.phhp.ufl.edu/training/bre...
Reposted by Mark C Turner
Reposted by Mark C Turner
In our February issue: Daniel J. Drucker discusses the expanding applications of therapies based on #GLP1, outlining key papers from the past 12 months (£) go.nature.com/3WkhZ7g
January 16, 2025 at 11:37 AM
In our February issue: Daniel J. Drucker discusses the expanding applications of therapies based on #GLP1, outlining key papers from the past 12 months (£) go.nature.com/3WkhZ7g
Reposted by Mark C Turner
ICYMI: New content online: Exploring the functions of the myokine feimin
Exploring the functions of the myokine feimin
Nature Reviews Endocrinology, Published online: 15 January 2025; doi:10.1038/s41574-025-01086-zExploring the functions of the myokine feimin
go.nature.com
January 17, 2025 at 4:30 PM
ICYMI: New content online: Exploring the functions of the myokine feimin
Reposted by Mark C Turner
Read our latest Methods article! Godwin et al evaluate common methods to analyse #skeletal #muscle #ribosomes and quantify total RNA and also present a novel RiboAb antibody cocktail method.
doi.org/10.14814/phy...
#MyoBlue #RNA
doi.org/10.14814/phy...
#MyoBlue #RNA
January 9, 2025 at 10:04 PM
Read our latest Methods article! Godwin et al evaluate common methods to analyse #skeletal #muscle #ribosomes and quantify total RNA and also present a novel RiboAb antibody cocktail method.
doi.org/10.14814/phy...
#MyoBlue #RNA
doi.org/10.14814/phy...
#MyoBlue #RNA
Reposted by Mark C Turner
🚨 Closing date next week to apply to do a PhD with me at Oxford Brookes.
www.jobs.ac.uk/job/DKY307/n...
www.jobs.ac.uk/job/DKY307/n...
Nigel Groome Studentship: Investigating The Role of Non-coding RNAs in Patient Pancreatic Neuroendocrine Tumour Cells, Extracellular Vesicles and Blood Samples and Their Function in Cancer Development...
Discover a Nigel Groome Studentship: Investigating The Role of Non-coding RNAs in Patient Pancreatic Neuroendocrine Tumour Cells, Extracellular Vesicles and Blood Samples and Their Function in Cancer ...
www.jobs.ac.uk
January 8, 2025 at 1:09 PM
🚨 Closing date next week to apply to do a PhD with me at Oxford Brookes.
www.jobs.ac.uk/job/DKY307/n...
www.jobs.ac.uk/job/DKY307/n...
Reposted by Mark C Turner
The Education Committee of the @CancerCachexia Society invites you to our seminar on January 15 at 12:00 pm EST with Andrea Bonetto, University of Colorado, US.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.
January 8, 2025 at 2:28 PM
The Education Committee of the @CancerCachexia Society invites you to our seminar on January 15 at 12:00 pm EST with Andrea Bonetto, University of Colorado, US.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.
Reposted by Mark C Turner
Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative - Communications Biology
Optimized methods and protocols for single cell and single nucleus RNA sequencing of preserved skeletal muscle provide an important resource for obtaining high-quality single cell genomic material fro...
www.nature.com
January 5, 2025 at 7:23 PM
Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Mark C Turner
Reposted by Mark C Turner
We’ll be continuing to award JCS-FocalPlane Training Grants in 2025. They are open to ECRs that otherwise wouldn’t have sufficient funding to attend a microscopy or bioimage analysis course to support their research in cell biology.
www.biologists.com/grants/jcs-f...
@jcellsci.bsky.social
www.biologists.com/grants/jcs-f...
@jcellsci.bsky.social
December 20, 2024 at 1:53 PM
We’ll be continuing to award JCS-FocalPlane Training Grants in 2025. They are open to ECRs that otherwise wouldn’t have sufficient funding to attend a microscopy or bioimage analysis course to support their research in cell biology.
www.biologists.com/grants/jcs-f...
@jcellsci.bsky.social
www.biologists.com/grants/jcs-f...
@jcellsci.bsky.social