Manuel Friese
@manuelfriese.bsky.social
Professor of Neurology | Director Institute of Neuroimmunology and Multiple Sclerosis, UKE
Reposted by Manuel Friese
👉 Register now: hubs.li/Q03NdTNP0
📆 Nov 20, 2025 | 2pm GMT / 9am EST / 10pm CST
Join our expert panel as they explore innate immunity’s role in neurological diseases, and therapies to prevent inflammation-driven neurodegeneration.
#neurology #brainhealth #lancetwebinar
📆 Nov 20, 2025 | 2pm GMT / 9am EST / 10pm CST
Join our expert panel as they explore innate immunity’s role in neurological diseases, and therapies to prevent inflammation-driven neurodegeneration.
#neurology #brainhealth #lancetwebinar
November 5, 2025 at 7:50 AM
👉 Register now: hubs.li/Q03NdTNP0
📆 Nov 20, 2025 | 2pm GMT / 9am EST / 10pm CST
Join our expert panel as they explore innate immunity’s role in neurological diseases, and therapies to prevent inflammation-driven neurodegeneration.
#neurology #brainhealth #lancetwebinar
📆 Nov 20, 2025 | 2pm GMT / 9am EST / 10pm CST
Join our expert panel as they explore innate immunity’s role in neurological diseases, and therapies to prevent inflammation-driven neurodegeneration.
#neurology #brainhealth #lancetwebinar
Our latest work:
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
Neuronal proteasomal dysfunction is a hallmark of neuroinflammatory and neurodegenerative
diseases. This study reveals that the interferon-induced immunoproteasome drastically
decreases proteasomal ac...
www.cell.com
June 17, 2025 at 7:18 PM
Our latest work:
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...
Reposted by Manuel Friese
Interferon-induced immunoproteasome drastically decreases proteasomal activity in neurons, leading to a switch in neuronal metabolism with increased oxidative injury and ferroptosis @cellcellpress.bsky.social @manuelfriese.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
June 17, 2025 at 4:44 PM
Interferon-induced immunoproteasome drastically decreases proteasomal activity in neurons, leading to a switch in neuronal metabolism with increased oxidative injury and ferroptosis @cellcellpress.bsky.social @manuelfriese.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Manuel Friese
We’re looking for a physician (f/m/d) with a strong interest in neuroimmunology and research in our MS outpatient clinic and day hospital team!
Join us in advancing care and science in a dynamic, interdisciplinary environment🧠
uke.jobs/index.php?ac...
Join us in advancing care and science in a dynamic, interdisciplinary environment🧠
uke.jobs/index.php?ac...
Arzt/Ärztin (all genders) in Weiterbildung - Neurologie mit Schwerpunkt Neuroimmunologie
uke.jobs
June 6, 2025 at 2:00 PM
We’re looking for a physician (f/m/d) with a strong interest in neuroimmunology and research in our MS outpatient clinic and day hospital team!
Join us in advancing care and science in a dynamic, interdisciplinary environment🧠
uke.jobs/index.php?ac...
Join us in advancing care and science in a dynamic, interdisciplinary environment🧠
uke.jobs/index.php?ac...
Reposted by Manuel Friese
Important walkthrough for newcomers in the field
rdcu.be/eg58p
rdcu.be/eg58p
Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...
rdcu.be
April 9, 2025 at 8:21 PM
Important walkthrough for newcomers in the field
rdcu.be/eg58p
rdcu.be/eg58p
Reposted by Manuel Friese
This week in #Science #Immunology: researchers @ @helsinki.fi characterize #immune landscape of deep cervical #LymphNodes in newly diagnosed untreated patients w #MultipleSclerosis! Authors uncover several lines of evidence strengthening possible link btw #MS & Epstein–Barr virus ( #EBV ) infection!
Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
Deep cervical lymph nodes of patients with MS have an altered B cell compartment that, in part, transcriptionally resembles an EBV infection.
www.science.org
February 21, 2025 at 8:38 PM
This week in #Science #Immunology: researchers @ @helsinki.fi characterize #immune landscape of deep cervical #LymphNodes in newly diagnosed untreated patients w #MultipleSclerosis! Authors uncover several lines of evidence strengthening possible link btw #MS & Epstein–Barr virus ( #EBV ) infection!
We are hiring (2 positions) one
Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf
uke.jobs/index.php?ac...
uke.jobs/index.php?ac...
Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf
uke.jobs/index.php?ac...
uke.jobs/index.php?ac...
January 28, 2025 at 8:39 AM
We are hiring (2 positions) one
Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf
uke.jobs/index.php?ac...
uke.jobs/index.php?ac...
Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf
uke.jobs/index.php?ac...
uke.jobs/index.php?ac...
Check out our results from an academic drug development program targeting TRPM4 to protect neurons from neurodegeneration. Many years of intense collaboration between UKE Hamburg, KU Leuven, Fraunhofer ITMP, Evotec:
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
December 4, 2024 at 11:37 AM
Check out our results from an academic drug development program targeting TRPM4 to protect neurons from neurodegeneration. Many years of intense collaboration between UKE Hamburg, KU Leuven, Fraunhofer ITMP, Evotec:
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...