Lori Benedict BSN RN CDCES CMES
@mandaloriann.bsky.social
Nurse, Diabetes, Glucose Goddess, Kidney Transplant
Wife, Mother, Personal Trainer, Cycologist 🚴♀️, Overthinker
Wife, Mother, Personal Trainer, Cycologist 🚴♀️, Overthinker
Reposted by Lori Benedict BSN RN CDCES CMES
On the cusp of closing the genetic association and mechanism gap while laying the foundation for future precision medicine approaches in type 2 #diabetes #genetics @diabetologiajnl.bsky.social link.springer.com/article/10.1...
Bridging the variant-to-function gap in type 2 diabetes: advances and challenges - Diabetologia
Type 2 diabetes is a polygenic, heterogeneous disease affecting over 530 million individuals worldwide, a number projected to rise to 1.3 billion by 2050. Genome-wide association studies have identifi...
link.springer.com
November 22, 2025 at 8:54 PM
On the cusp of closing the genetic association and mechanism gap while laying the foundation for future precision medicine approaches in type 2 #diabetes #genetics @diabetologiajnl.bsky.social link.springer.com/article/10.1...
this is the year I send out holiday cards
November 5, 2025 at 1:06 AM
this is the year I send out holiday cards
Reposted by Lori Benedict BSN RN CDCES CMES
Reporters must stop accepting this. Options:
-Laughing at him. Long and hard (combine with others)
-"It's your job to be informed"
-"How can Americans take you seriously when you always claim ignorance?"
-"I've never heard a speaker claim ignorance so often"
-"Nancy Pelosi knew what was happening"
-Laughing at him. Long and hard (combine with others)
-"It's your job to be informed"
-"How can Americans take you seriously when you always claim ignorance?"
-"I've never heard a speaker claim ignorance so often"
-"Nancy Pelosi knew what was happening"
Q: Just last week a minister was shot directly in the face with a pepper round by a DHS agent that left his face bloodied. Are you concerned that this is a religious freedom issue?
MIKE JOHNSON: I can't comment on any of those instances. I haven't seen or heard any of those videos
MIKE JOHNSON: I can't comment on any of those instances. I haven't seen or heard any of those videos
October 29, 2025 at 10:01 PM
Reporters must stop accepting this. Options:
-Laughing at him. Long and hard (combine with others)
-"It's your job to be informed"
-"How can Americans take you seriously when you always claim ignorance?"
-"I've never heard a speaker claim ignorance so often"
-"Nancy Pelosi knew what was happening"
-Laughing at him. Long and hard (combine with others)
-"It's your job to be informed"
-"How can Americans take you seriously when you always claim ignorance?"
-"I've never heard a speaker claim ignorance so often"
-"Nancy Pelosi knew what was happening"
Reposted by Lori Benedict BSN RN CDCES CMES
⏩ Next #NephJC is on IgA nephropathy @kdigo.org guideline
🎨 Nice visual summary by @roxnonna23.bsky.social
www.nephjc.com/news/2025/10...
🎨 Nice visual summary by @roxnonna23.bsky.social
www.nephjc.com/news/2025/10...
KDIGO 2025 IgA guidelines - Visual Abstract — NephJC
KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection. Check out the visual abstract created by Natalia Nombera
www.nephjc.com
October 27, 2025 at 5:27 PM
⏩ Next #NephJC is on IgA nephropathy @kdigo.org guideline
🎨 Nice visual summary by @roxnonna23.bsky.social
www.nephjc.com/news/2025/10...
🎨 Nice visual summary by @roxnonna23.bsky.social
www.nephjc.com/news/2025/10...
Reposted by Lori Benedict BSN RN CDCES CMES
This 2017 HuffPo piece contains more wisdom & insight on current politics than 1000000 consultant polling reports.
I Don't Know How To Explain To You That You Should Care About Other People
Our disagreement is not merely political, but a fundamental divide on what it means to live in a society.
www.huffpost.com
October 27, 2025 at 7:46 PM
This 2017 HuffPo piece contains more wisdom & insight on current politics than 1000000 consultant polling reports.
Reposted by Lori Benedict BSN RN CDCES CMES
Turns out that if you lose weight you feel better dom-pubs.onlinelibrary.wiley.com/doi/10.1111/...
Weight‐reducing treatments are associated with an improvement in depression, functional health status, and quality of life: A meta‐analysis of randomized controlled trials
Aim
To assess whether there is a beneficial or detrimental effect of weight reduction on mental health.
Materials and methods
Meta-analysis of randomized trials performed for weight loss, in which.....
dom-pubs.onlinelibrary.wiley.com
October 24, 2025 at 9:49 PM
Turns out that if you lose weight you feel better dom-pubs.onlinelibrary.wiley.com/doi/10.1111/...
headed out to shop for a blue and white polka dot dress
October 24, 2025 at 10:11 PM
headed out to shop for a blue and white polka dot dress
Reposted by Lori Benedict BSN RN CDCES CMES
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
October 22, 2025 at 10:44 PM
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
Has anyone checked on Dolly Parton lately?
October 22, 2025 at 10:48 PM
Has anyone checked on Dolly Parton lately?
Reposted by Lori Benedict BSN RN CDCES CMES
My feelings, exactly.
October 19, 2025 at 10:27 PM
My feelings, exactly.
every. fkn. time.
October 17, 2025 at 8:43 PM
every. fkn. time.
Reposted by Lori Benedict BSN RN CDCES CMES
Top 10 Rally Reminders for #NoKingsDayOct18th
October 16, 2025 at 12:58 PM
Top 10 Rally Reminders for #NoKingsDayOct18th
Reposted by Lori Benedict BSN RN CDCES CMES
What happens when your body suddenly stops making the one hormone that keeps your blood sugar in check?
The 2,000-Year Journey to Understanding Type 1 Diabetes—And What’s Next
What happens when your body suddenly stops making the one hormone that keeps your blood sugar in check?
www.scientificamerican.com
October 14, 2025 at 6:42 PM
What happens when your body suddenly stops making the one hormone that keeps your blood sugar in check?
Reposted by Lori Benedict BSN RN CDCES CMES
A new drug slows insulin-dependent diabetic deterioration and has sped up development of a complete remedy
A New Drug Slows the Worsening of Type 1 Diabetes and Has Sped up Work on a Full Cure
A new drug slows insulin-dependent diabetic deterioration and has sped up development of a complete remedy
www.scientificamerican.com
October 14, 2025 at 1:57 PM
A new drug slows insulin-dependent diabetic deterioration and has sped up development of a complete remedy
Reposted by Lori Benedict BSN RN CDCES CMES
Inflammation is a key driver of the pathophysiology of cardiometabolic disorders #obesity #T2D and new metabolic medicines based on GLP-1 action exert their magic in part by reducing inflammation. A new review from Professor Donath summarizes the field www.sciencedirect.com/science/arti...?
Obesity, diabetes, and inflammation: Pathophysiology and clinical implications
Obesity and its related disorders, including type 2 diabetes and liver, kidney, and cardiovascular diseases, are now recognized as chronic inflammator…
www.sciencedirect.com
October 3, 2025 at 3:23 PM
Inflammation is a key driver of the pathophysiology of cardiometabolic disorders #obesity #T2D and new metabolic medicines based on GLP-1 action exert their magic in part by reducing inflammation. A new review from Professor Donath summarizes the field www.sciencedirect.com/science/arti...?
Reposted by Lori Benedict BSN RN CDCES CMES
GLP-1 medicines and #arthritis www.nature.com/articles/s41...
Glucagon-like peptide-1 receptor agonists in arthritis: current insights and future directions - Nature Reviews Rheumatology
Evidence is emerging that glucagon-like peptide-1 (GLP-1) receptor agonists have anti-inflammatory and chondroprotective properties independent of their effects on weight loss. In this Review, the authors discuss the potential effects of GLP-1 receptor agonists on the incidence, disease activity and progression of various forms of arthritis, as well as practical considerations for their use in this context.
www.nature.com
October 1, 2025 at 10:24 AM
GLP-1 medicines and #arthritis www.nature.com/articles/s41...
Reposted by Lori Benedict BSN RN CDCES CMES
Do you want to decrease your chance of dying? Take tirzepatide.
Do you want to preserve kidney function? Tirzepatide.
My latest blog post on the remarkable data from the SURPASS CVOT trial.
We live in a time of medical miracles.
Please read and share
Do you want to preserve kidney function? Tirzepatide.
My latest blog post on the remarkable data from the SURPASS CVOT trial.
We live in a time of medical miracles.
Please read and share
GIP: SURPASSing all expectations
Part 3 of the GIP series, cardiac benefits of GIP and a deep dive of the remarkable SURPASS CVOT trial results
the-incretins.beehiiv.com
September 29, 2025 at 3:00 PM
Do you want to decrease your chance of dying? Take tirzepatide.
Do you want to preserve kidney function? Tirzepatide.
My latest blog post on the remarkable data from the SURPASS CVOT trial.
We live in a time of medical miracles.
Please read and share
Do you want to preserve kidney function? Tirzepatide.
My latest blog post on the remarkable data from the SURPASS CVOT trial.
We live in a time of medical miracles.
Please read and share
Reposted by Lori Benedict BSN RN CDCES CMES
Clinical trial results reporting for industry-still room for improvement. Meanwhile in academia, home to many industry critics, the timely reporting rates remain abysmal publichealth.realclearjournals.org/research-art...
Sponsor-Level Compliance with ClinicalTrials.gov Reporting Requirements: A Comprehensive Analysis
Transparency in clinical research is essential for advancing medical knowledge, informing healthcare decisions, and maintaining public trust. The Food and Drug Administration Amendments Act (FDAAA) of...
publichealth.realclearjournals.org
September 26, 2025 at 7:56 PM
Clinical trial results reporting for industry-still room for improvement. Meanwhile in academia, home to many industry critics, the timely reporting rates remain abysmal publichealth.realclearjournals.org/research-art...
Reposted by Lori Benedict BSN RN CDCES CMES
The projected rise in global cancer deaths
1990 —5.9 million
2023—10.4 million
2050—18.8 million
is yet another reason we need to get primary prevention into high gear, which is now possible but not getting done
www.thelancet.com/journals/lan...
1990 —5.9 million
2023—10.4 million
2050—18.8 million
is yet another reason we need to get primary prevention into high gear, which is now possible but not getting done
www.thelancet.com/journals/lan...
September 24, 2025 at 10:38 PM
The projected rise in global cancer deaths
1990 —5.9 million
2023—10.4 million
2050—18.8 million
is yet another reason we need to get primary prevention into high gear, which is now possible but not getting done
www.thelancet.com/journals/lan...
1990 —5.9 million
2023—10.4 million
2050—18.8 million
is yet another reason we need to get primary prevention into high gear, which is now possible but not getting done
www.thelancet.com/journals/lan...
Reposted by Lori Benedict BSN RN CDCES CMES
GLP-1 medicines #weightloss #obesity and frailty. Insights from the STEP HFpEF trials with reduction of frailty endpoints after semaglutide www.sciencedirect.com/science/arti...
Frailty and Effects of Semaglutide in Obesity-Related HFpEF: Findings From the STEP-HFpEF Program
Frailty is common in heart failure with preserved ejection fraction (HFpEF). In the STEP-HFpEF (Research Study to Investigate How Well Semaglutide Wor…
www.sciencedirect.com
September 19, 2025 at 2:48 PM
GLP-1 medicines #weightloss #obesity and frailty. Insights from the STEP HFpEF trials with reduction of frailty endpoints after semaglutide www.sciencedirect.com/science/arti...
Reposted by Lori Benedict BSN RN CDCES CMES
For all my #NephJC friends please note this that in high risk CKD Tirzepatide STOPPED GFR decline for 2 years! And that's not a placebo comparison. That's against dulaglutide. That's incredible.
Even in the general population it delayed GFR decline for about a year.
Even in the general population it delayed GFR decline for about a year.
Then THESE two slides especially are exciting for renal outcomes. In the high risk CKD population tirzepatide actually stalls out GFR decline for nearly TWO YEARS. Thats a huge benefit for mortality. Same for general population the GFR decline is lower indication Tirz is preserving renal function.
September 18, 2025 at 11:11 PM
For all my #NephJC friends please note this that in high risk CKD Tirzepatide STOPPED GFR decline for 2 years! And that's not a placebo comparison. That's against dulaglutide. That's incredible.
Even in the general population it delayed GFR decline for about a year.
Even in the general population it delayed GFR decline for about a year.
Reposted by Lori Benedict BSN RN CDCES CMES
What's happening with Jimmy Kimmel is about politics and power.
September 19, 2025 at 1:04 AM
What's happening with Jimmy Kimmel is about politics and power.