m-zampieri.bsky.social
@m-zampieri.bsky.social
Reposted
I have been loudly, persistently anti-Trump since the beginning. And tonight's election results just make me more sure: *there are more of us than there are of them* A good hard look at Trumpism in action has made that impossible to ignore.

Let's take this country back, and let's make it better.
November 5, 2025 at 2:37 AM
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Catching up on some blog topics: how do you get things past the weird defenses of tuberculosis bacteria, anyway?
Tuberculosis Defenses
www.science.org
October 9, 2025 at 3:13 PM
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We have people in power making broad claims around certain drugs and autism that have been continuously disproven.
September 25, 2025 at 2:02 PM
We are extremely happy to share our new work on glutamine addiction in cancer cells. www.biorxiv.org/content/10.1...
Looking forward to your feedbacks
The glutamine-aspartate metabolic tradeoff between fast growth and metabolic flexibility.
Cancer cells develop unique addictions to nutrients offering attractive opportunities for clinical intervention. However, how cancer cells orchestrate and benefit from metabolic rewiring remain fundam...
www.biorxiv.org
May 13, 2025 at 6:21 AM
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No matter what you think of the Israel/Palestine situation, and no matter what you think of the Columbia Univ. protests:

If ICE can grab a permanent resident, suddenly revoke their Green Card (!) and whisk them away to a distant prison incommunicado, no one’s liberties are really safe.
Uses the word "proudly" in the first sentence. Says it is the "first arrest of many to come" in the second sentence.

If you think this ends with "Hamas Students" you are not paying attention
Trump takes credit for Mahmoud Khalil's arrest by ICE:
March 10, 2025 at 6:57 PM
Our work is now featured in The Scientist! Thanks Sneha Khedkar for such a clear and exciting presentation of our research.

www.the-scientist.com/same-drug-ne...
Same Drug, New Actions: Metabolomics Reveals Hidden Drug Effects
Studying drug-induced metabolic changes with high-throughput systems shed light on drug modes of action, providing an efficient drug discovery platform.
www.the-scientist.com
March 6, 2025 at 2:48 PM
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For decades people have searched for the vascular target of the widely used thiazide blood pressure drugs. Looks like it’s been found!
The Thiazide Target, At Last
www.science.org
February 25, 2025 at 6:01 PM
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Sad to know about the passing of Béla Novák. This review from Tyson, Chen and Novak was such a revelation for me as an introduction to control theory in biological systems. A classic that will remain relevant for many years to come. www.sciencedirect.com/science/arti...
February 25, 2025 at 6:30 PM
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February 13, 2025 at 8:09 AM
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We are seeking for a talented semester or master student for a computational project on antimicrobial effects of drugs. Check it out!

www.zampierilab.org/join-us/
Join us - Zampieri Lab
Interested to join our lab? Feel free to inquire about open positions or semester/master projects in our lab. We are always looking for highly motivated Master and Bachelor Students. We continuously o...
www.zampierilab.org
February 12, 2025 at 11:26 AM
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Exciting news from the Apostolova lab
@biomedizin.unibas.ch! A study by Petya Apostolova & Robert Zeiser shows extracorporeal photopheresis is effective in treating immune-related adverse events from checkpoint inhibitors. www.cell.com/cancer-cell/...

#CancerResearch #Immunotherapy #ECP #ICI #irAE
February 10, 2025 at 7:00 PM
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📢📜 Celebrating some fantastic recent papers from our people!

Rentsch Lab @nccr-antiresist.bsky.social 👉 onlinelibrary.wiley.com/doi/10.1002/...

Bumann Lab 👉 www.nature.com/articles/s41...

Zampieri Lab 👉 nature.com/articles/s41...

@knutdrescher.bsky.social Lab 👉 www.nature.com/articles/s41...
February 6, 2025 at 10:52 AM
Our work was featured in chemistryworld. Fantastic pitch of our research by @AntonyJKing

www.chemistryworld.com/news/mapping...
Mapping metabolite disturbances by drugs
High-throughput metabolomic profiling gives insight into unpredictable drug effects
www.chemistryworld.com
February 5, 2025 at 2:15 PM
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Delighted to share our latest paper describing a method to read the levels of hundreds of metabolites or drugs in parallel using DNA sequencing. This method, which we call ‘smol-seq’ (Small MOLecule sequencing), harnesses the power of DNA sequencing for metabolite detection:
rdcu.be/d8xLv (1/6)
Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing
Nature Biotechnology - Metabolites can be quantified using a combination of aptamers and DNA barcodes.
rdcu.be
February 4, 2025 at 1:54 PM
Really nice work!! www.cell.com/action/showP...
www.cell.com
January 30, 2025 at 1:23 PM
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Fantastic work by @zampierilab.bsky.social‬ (formerly at IMSB) on studying drug mode of action using large scale metabolic profiling.
We are very excited to share that the recent research from our lab has been published in Nature Biotechnology!

Thanks to our lab members and our collaborators for contributing to this project and especially to Laurentz for driving this exciting research!
www.nature.com/articles/s41...
A human metabolic map of pharmacological perturbations reveals drug modes of action - Nature Biotechnology
Mapping the metabolic effects of drugs helps define their mode of action.
www.nature.com
January 28, 2025 at 4:44 PM
Reposted
We are very excited to share that the recent research from our lab has been published in Nature Biotechnology!

Thanks to our lab members and our collaborators for contributing to this project and especially to Laurentz for driving this exciting research!
www.nature.com/articles/s41...
A human metabolic map of pharmacological perturbations reveals drug modes of action - Nature Biotechnology
Mapping the metabolic effects of drugs helps define their mode of action.
www.nature.com
January 28, 2025 at 11:24 AM