@lutfia95.bsky.social
Bioinformatician and C/C++ lover. Interested in computational biology and fast algorithms.
Reposted
New review article out!
Metaproteomics of human microbiota: progress and key challenges for precision medicine
Link:
www.sciencedirect.com/science/arti...
#Metaproteomics #TeamMassSpec #Microbiome
Metaproteomics of human microbiota: progress and key challenges for precision medicine
Link:
www.sciencedirect.com/science/arti...
#Metaproteomics #TeamMassSpec #Microbiome
a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''
ALT: a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''
media.tenor.com
May 25, 2025 at 5:16 AM
New review article out!
Metaproteomics of human microbiota: progress and key challenges for precision medicine
Link:
www.sciencedirect.com/science/arti...
#Metaproteomics #TeamMassSpec #Microbiome
Metaproteomics of human microbiota: progress and key challenges for precision medicine
Link:
www.sciencedirect.com/science/arti...
#Metaproteomics #TeamMassSpec #Microbiome
Reposted
Short-read metagenomic sequencing cannot recover genomes from many abundant marine prokaryotes due to high strain heterogeneity and platform-inherent GC bias (likely viruses, too), but Nanopore long reads can address this. A results thread on our recent preprint 🧵.
May 25, 2025 at 10:27 AM
Short-read metagenomic sequencing cannot recover genomes from many abundant marine prokaryotes due to high strain heterogeneity and platform-inherent GC bias (likely viruses, too), but Nanopore long reads can address this. A results thread on our recent preprint 🧵.
Reposted
Correct FDR control in proteomics is tricky, and this @natmethods.nature.com study by Wen et. al is a great example highlighting the specific challenges. It provides a formal framework to evaluate entrapment estimation methods. Fantastic read!
Error control in proteomics mass spectrometry analysis is hard. We came up with a way to evaluate error control. Upshot: for old-school DDA data, not so bad. For DIA data, no existing tool successfully controls the false discovery rate!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment - Nature Methods
A theoretical foundation for entrapment methods is presented, along with a method that enables more accurate evaluation of false discovery rate (FDR) control in proteomics mass spectrometry analysis p...
www.nature.com
June 16, 2025 at 9:20 PM
Correct FDR control in proteomics is tricky, and this @natmethods.nature.com study by Wen et. al is a great example highlighting the specific challenges. It provides a formal framework to evaluate entrapment estimation methods. Fantastic read!
Reposted
Foundation Model for MS Proteomics - Preprint out:
arxiv.org/abs/2505.10848
arxiv.org/abs/2505.10848
Foundation model for mass spectrometry proteomics
Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrument...
arxiv.org
May 19, 2025 at 8:46 PM
Foundation Model for MS Proteomics - Preprint out:
arxiv.org/abs/2505.10848
arxiv.org/abs/2505.10848
Reposted
MegaPX: fast and space-efficient peptide assignment method using IBF-based multi-indexing https://www.biorxiv.org/content/10.1101/2025.04.14.648734v1
April 20, 2025 at 4:47 AM
MegaPX: fast and space-efficient peptide assignment method using IBF-based multi-indexing https://www.biorxiv.org/content/10.1101/2025.04.14.648734v1
Reposted
MegaPX: fast and space-efficient peptide assignment method using IBF-based multi-indexing https://www.biorxiv.org/content/10.1101/2025.04.14.648734v1
April 20, 2025 at 4:47 AM
MegaPX: fast and space-efficient peptide assignment method using IBF-based multi-indexing https://www.biorxiv.org/content/10.1101/2025.04.14.648734v1