Lizzie Dellar
@lizziedellar.bsky.social
Postdoc @mndoxford.bsky.social @ndcnoxford.bsky.social
working on protein biomarkers of ALS/MND and extracellular vesicles.
working on protein biomarkers of ALS/MND and extracellular vesicles.
Reposted by Lizzie Dellar
#ExtracellularVesicles in #TDP43 proteinopathies: pathogenesis and #biomarker potential
Elizabeth R. Dellar @lizziedellar.bsky.social Lara Nikel, Stephanie Fowler...Alexander G. Thompson #exosome #ALS #FTD
molecularneurodegeneration.biomedcentral.com/articles/10....
Elizabeth R. Dellar @lizziedellar.bsky.social Lara Nikel, Stephanie Fowler...Alexander G. Thompson #exosome #ALS #FTD
molecularneurodegeneration.biomedcentral.com/articles/10....
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...
molecularneurodegeneration.biomedcentral.com
June 10, 2025 at 5:01 PM
#ExtracellularVesicles in #TDP43 proteinopathies: pathogenesis and #biomarker potential
Elizabeth R. Dellar @lizziedellar.bsky.social Lara Nikel, Stephanie Fowler...Alexander G. Thompson #exosome #ALS #FTD
molecularneurodegeneration.biomedcentral.com/articles/10....
Elizabeth R. Dellar @lizziedellar.bsky.social Lara Nikel, Stephanie Fowler...Alexander G. Thompson #exosome #ALS #FTD
molecularneurodegeneration.biomedcentral.com/articles/10....
Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE.
doi.org/10.1186/s130...
doi.org/10.1186/s130...
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...
doi.org
June 10, 2025 at 2:53 PM
Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE.
doi.org/10.1186/s130...
doi.org/10.1186/s130...
Reposted by Lizzie Dellar
“The time to write a fellowship is when it feels right for you.” Great advice from @dryvonnecouch.bsky.social’s new guest blog on writing your first fellowship.
www.dementiaresearcher.nihr.ac.uk/blog-writing...
www.dementiaresearcher.nihr.ac.uk/blog-writing...
Dr Yvonne Couch - Blog – Writing Your First Fellowship
Dr Yvonne Couch shares wisdom (and warnings) on writing your first fellowship application — from timing and ideas to funding and salary tips.
www.dementiaresearcher.nihr.ac.uk
April 11, 2025 at 9:53 AM
“The time to write a fellowship is when it feels right for you.” Great advice from @dryvonnecouch.bsky.social’s new guest blog on writing your first fellowship.
www.dementiaresearcher.nihr.ac.uk/blog-writing...
www.dementiaresearcher.nihr.ac.uk/blog-writing...
Reposted by Lizzie Dellar
Also contributing were Beatrix with her poster on long-read sequencing of #C9orf72 HRE and @lizziedellar.bsky.social with her poster on #ExtracellularVesicle -based biomarker discovery in CSF.
March 27, 2025 at 11:00 AM
Also contributing were Beatrix with her poster on long-read sequencing of #C9orf72 HRE and @lizziedellar.bsky.social with her poster on #ExtracellularVesicle -based biomarker discovery in CSF.
Reposted by Lizzie Dellar
The @mndoxford.bsky.social team enjoyed the day at the Oxford #MDUK Neuromuscular Centre meeting yesterday. In the #ALS/#MND session Alex spoke on our
studies of at-risk pre-symptomatic populations, and Kevin on the path from pre-clinical models to experimental medicine.
studies of at-risk pre-symptomatic populations, and Kevin on the path from pre-clinical models to experimental medicine.
March 27, 2025 at 11:00 AM
The @mndoxford.bsky.social team enjoyed the day at the Oxford #MDUK Neuromuscular Centre meeting yesterday. In the #ALS/#MND session Alex spoke on our
studies of at-risk pre-symptomatic populations, and Kevin on the path from pre-clinical models to experimental medicine.
studies of at-risk pre-symptomatic populations, and Kevin on the path from pre-clinical models to experimental medicine.
Reposted by Lizzie Dellar
Excellent talk by Lizzie @lizziedellar.bsky.social from the group on discovery and validation of early biomarkers in #ALS at the Oxford Neuroscience Symposium this week.
March 21, 2025 at 12:35 PM
Excellent talk by Lizzie @lizziedellar.bsky.social from the group on discovery and validation of early biomarkers in #ALS at the Oxford Neuroscience Symposium this week.
Come and work with me! Research position open to work on isolation of #extracellular #vesicles for biomarker discovery in #ALS #MND. See link for more details, and reach out if you have questions. my.corehr.com/pls/uoxrecru...
January 24, 2025 at 1:22 PM
Come and work with me! Research position open to work on isolation of #extracellular #vesicles for biomarker discovery in #ALS #MND. See link for more details, and reach out if you have questions. my.corehr.com/pls/uoxrecru...
Reposted by Lizzie Dellar
Come and join us! Research assistant position open at @mndoxford.bsky.social @ndcnoxford.bsky.social, working on collecting neuroimaging data in #ALS and #FTD. Previous research experience with humans is essential. This post would suit a #Psychology or #Neuroscience graduate. See link below for info
Job Details
my.corehr.com
January 15, 2025 at 3:41 PM
Come and join us! Research assistant position open at @mndoxford.bsky.social @ndcnoxford.bsky.social, working on collecting neuroimaging data in #ALS and #FTD. Previous research experience with humans is essential. This post would suit a #Psychology or #Neuroscience graduate. See link below for info
Reposted by Lizzie Dellar
We also have several group members giving platform talks as well as a plenary lecture! We would be delighted to see you there - see below for our presenters and talks #MND #ALS @mndassoc.bsky.social #alsmndsymp
December 6, 2024 at 1:34 AM
We also have several group members giving platform talks as well as a plenary lecture! We would be delighted to see you there - see below for our presenters and talks #MND #ALS @mndassoc.bsky.social #alsmndsymp
Reposted by Lizzie Dellar
We are excited to be here in Montreal for @mndassoc.bsky.social #alsmndsymp! We would be delighted to see you at our posters - see below for our presenters and poster numbers #MND #ALS
December 6, 2024 at 1:32 AM
We are excited to be here in Montreal for @mndassoc.bsky.social #alsmndsymp! We would be delighted to see you at our posters - see below for our presenters and poster numbers #MND #ALS
Reposted by Lizzie Dellar
@mndoxford.bsky.social is now also here on Bluesky. Give it a follow to hear research updates from the whole Oxford MND Centre!
November 22, 2024 at 11:09 AM
@mndoxford.bsky.social is now also here on Bluesky. Give it a follow to hear research updates from the whole Oxford MND Centre!
Congrats to Steph Fowler and team for their excellent work showing the presence of tau filaments in #extracellularvesicles derived from brain tissue in Alzheimer's disease, out in @NatureNeuro today. www.nature.com/articles/s41... Excited to see more on this!
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease - Nature Neuroscience
Using cryo-electron tomography (cryo-ET) and proteomics, this study identifies the tethering of pathological tau filaments within defined brain extracellular vesicles in Alzheimer’s disease, shining l...
www.nature.com
November 21, 2024 at 5:03 PM
Congrats to Steph Fowler and team for their excellent work showing the presence of tau filaments in #extracellularvesicles derived from brain tissue in Alzheimer's disease, out in @NatureNeuro today. www.nature.com/articles/s41... Excited to see more on this!
Reposted by Lizzie Dellar
Here's number 2:
(hopefully by now you have figured out where to find them and can head over and browse at your leisure!)
www.dementiaresearcher.nihr.ac.uk/guest-blog-i...
(hopefully by now you have figured out where to find them and can head over and browse at your leisure!)
www.dementiaresearcher.nihr.ac.uk/guest-blog-i...
Dr Yvonne Couch - Is Leadership Important In Science?
Dr Yvonne Couch talks about leadership in research, exploring different styles and approaches and how you might apply them.
www.dementiaresearcher.nihr.ac.uk
November 11, 2024 at 9:51 AM
Here's number 2:
(hopefully by now you have figured out where to find them and can head over and browse at your leisure!)
www.dementiaresearcher.nihr.ac.uk/guest-blog-i...
(hopefully by now you have figured out where to find them and can head over and browse at your leisure!)
www.dementiaresearcher.nihr.ac.uk/guest-blog-i...
Reposted by Lizzie Dellar
This week’s Science Without Anguish post is out: the slippery slope to imposter syndrome in research and how to escape it.
Please tell your colleagues on or off social media. 🧪
www.sciencewithoutanguish.com/blog/we-are-...
Please tell your colleagues on or off social media. 🧪
www.sciencewithoutanguish.com/blog/we-are-...
November 18, 2024 at 6:07 PM
This week’s Science Without Anguish post is out: the slippery slope to imposter syndrome in research and how to escape it.
Please tell your colleagues on or off social media. 🧪
www.sciencewithoutanguish.com/blog/we-are-...
Please tell your colleagues on or off social media. 🧪
www.sciencewithoutanguish.com/blog/we-are-...
Reposted by Lizzie Dellar
EV people unite! 😁
First attempt at a starter pack for EV people - surprisingly difficult to find everyone!
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
Comment if you want to be added to the list 👇
#extracellularvesicles #exosomes #microvesicles
November 19, 2024 at 5:26 PM
EV people unite! 😁
Reposted by Lizzie Dellar
PXD051859 🚨
Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 levels in asymptomatic C9orf72 hexanucleotide repeat expansion carriers.
🚨 New dataset alert! 🚨
Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 levels in asymptomatic C9orf72 hexanucleotide repeat expansion carriers.
🚨 New dataset alert! 🚨
November 19, 2024 at 7:05 PM
PXD051859 🚨
Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 levels in asymptomatic C9orf72 hexanucleotide repeat expansion carriers.
🚨 New dataset alert! 🚨
Elevated cerebrospinal fluid ubiquitin carboxyl-terminal hydrolase isozyme L1 levels in asymptomatic C9orf72 hexanucleotide repeat expansion carriers.
🚨 New dataset alert! 🚨
(1/3) Happy to share our new work assessing protein changes in CSF of 48 asymptomatic C9orf72 variant carriers at higher risk of #ALS and #FTD.
We find an elevation in levels of UCHL1 protein, even in the absence of elevation in #neurofilament (NFL).
onlinelibrary.wiley.com/doi/full/10....
We find an elevation in levels of UCHL1 protein, even in the absence of elevation in #neurofilament (NFL).
onlinelibrary.wiley.com/doi/full/10....
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl‐Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers
Objective To identify biochemical changes in individuals at higher risk of developing amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD) via C9orf72 hexanucleotide repeat expansion...
onlinelibrary.wiley.com
November 18, 2024 at 10:44 AM
(1/3) Happy to share our new work assessing protein changes in CSF of 48 asymptomatic C9orf72 variant carriers at higher risk of #ALS and #FTD.
We find an elevation in levels of UCHL1 protein, even in the absence of elevation in #neurofilament (NFL).
onlinelibrary.wiley.com/doi/full/10....
We find an elevation in levels of UCHL1 protein, even in the absence of elevation in #neurofilament (NFL).
onlinelibrary.wiley.com/doi/full/10....