Lesly Calderón
@lesly-calderon.bsky.social
Group leader @Institute of Allergy Research @HelmholtzMunich
|| Interested in lymphocyte development, B-cell-mediated responses, molecular immunology || #LatinasinSTEM🇨🇺
|| Interested in lymphocyte development, B-cell-mediated responses, molecular immunology || #LatinasinSTEM🇨🇺
Reposted by Lesly Calderón
Plasma cells are the immune system’s antibody factories, producing the molecules that protect us after infection or vaccination. They originate from B cell. Yet how B cells make the switch to become plasma cells—and which genes control this transition—isn’t known.
Researchers from the lab of
Researchers from the lab of
January 29, 2026 at 8:20 AM
Plasma cells are the immune system’s antibody factories, producing the molecules that protect us after infection or vaccination. They originate from B cell. Yet how B cells make the switch to become plasma cells—and which genes control this transition—isn’t known.
Researchers from the lab of
Researchers from the lab of
Our manuscript "In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation" was just published in the @jem.org, @rupress.org!!!
@lesly-calderon.bsky.social, Busslinger et al. @impvienna.bsky.social describe an in vivo #CRISPR/Cas9 screening system for identifying novel regulators of B cell activation and plasma cell development in the context of the splenic microenvironment of immunized mice. rupress.org/jem/article/...
January 29, 2026 at 10:28 AM
Our manuscript "In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation" was just published in the @jem.org, @rupress.org!!!
Reposted by Lesly Calderón
Reposted by Lesly Calderón
Reposted by Lesly Calderón
Plasma cells are the immune system’s antibody factories, and they originate from B-cells.
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
January 29, 2026 at 8:20 AM
Plasma cells are the immune system’s antibody factories, and they originate from B-cells.
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
Reposted by Lesly Calderón
In @jem.org, @lesly-calderon.bsky.social et al. @impvienna.bsky.social describe an in vivo #CRISPR/Cas9 screening system for identifying novel regulators of B cell activation and plasma cell development in the context of the splenic microenvironment of immunized mice. rupress.org/jem/article/...
January 28, 2026 at 6:45 PM
In @jem.org, @lesly-calderon.bsky.social et al. @impvienna.bsky.social describe an in vivo #CRISPR/Cas9 screening system for identifying novel regulators of B cell activation and plasma cell development in the context of the splenic microenvironment of immunized mice. rupress.org/jem/article/...