Leiden Early Drug Discovery & Development (LED3)
@led3hub.bsky.social
LED3 is a hub of scientists working on early drug discovery at the Leiden Institute of Chemistry, the Leiden Academic Centre for Drug Research, the Institute of Biology Leiden and the Leiden Institute of Advanced Computer Science. @LED3hub@mstdn.science
Also check out the accompanying News and Views article that gives a concise overview of the study: www.nature.com/articles/s41...
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A pipeline for proteome-wide analysis of electrophile selectivity - Nature Chemistry
In the growing field of chemical proteomics, there is a need for general methods to map the reactivity profiles of covalent probes in complex proteomes. Now, a completely unbiased proteomic workflow h...
www.nature.com
October 30, 2025 at 10:53 AM
Also check out the accompanying News and Views article that gives a concise overview of the study: www.nature.com/articles/s41...
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Reposted by Leiden Early Drug Discovery & Development (LED3)
If you want to learn more, also check out the "In the Pipeline" blog post by @dereklowe.bsky.social from when the preprint was released: www.science.org/content/blog...
CC: @led3hub.bsky.social, @leidenscience.bsky.social, @unileiden.bsky.social, @tum.de
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CC: @led3hub.bsky.social, @leidenscience.bsky.social, @unileiden.bsky.social, @tum.de
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Comprehensive Covalent Probe Time
I really enjoyed this new paper on ChemRxiv, a Munich/Michigan/Berkeley collaboration on reactive covalent groups and their profile across different proteins. There have been a number of papers addres...
www.science.org
October 30, 2025 at 10:27 AM
If you want to learn more, also check out the "In the Pipeline" blog post by @dereklowe.bsky.social from when the preprint was released: www.science.org/content/blog...
CC: @led3hub.bsky.social, @leidenscience.bsky.social, @unileiden.bsky.social, @tum.de
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CC: @led3hub.bsky.social, @leidenscience.bsky.social, @unileiden.bsky.social, @tum.de
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