Leiden Early Drug Discovery & Development (LED3)
@led3hub.bsky.social
LED3 is a hub of scientists working on early drug discovery at the Leiden Institute of Chemistry, the Leiden Academic Centre for Drug Research, the Institute of Biology Leiden and the Leiden Institute of Advanced Computer Science. @LED3hub@mstdn.science
Interesting Tuesday Talk at @leidenscience.bsky.social by Ilze Bot of our LED3 hub. Under the title "Breaking the cycle of heart attacks", she talked about her research into, why heart attacks are still a big threat, even in patients receiving treatment.
#ChemSky #ChemBio #DrugDiscovery
#ChemSky #ChemBio #DrugDiscovery
November 11, 2025 at 3:14 PM
Interesting Tuesday Talk at @leidenscience.bsky.social by Ilze Bot of our LED3 hub. Under the title "Breaking the cycle of heart attacks", she talked about her research into, why heart attacks are still a big threat, even in patients receiving treatment.
#ChemSky #ChemBio #DrugDiscovery
#ChemSky #ChemBio #DrugDiscovery
Jeroen Codee speaks at the #Reedijk Symposium: "A new twist in the tale - stereoselective glycosylation reactions for bacterial glycan assembly". Exciting insights into the importance of advanced glycosylation chemistries to make complex glycosides to better understand (bacterial) biology.
November 7, 2025 at 12:47 PM
Jeroen Codee speaks at the #Reedijk Symposium: "A new twist in the tale - stereoselective glycosylation reactions for bacterial glycan assembly". Exciting insights into the importance of advanced glycosylation chemistries to make complex glycosides to better understand (bacterial) biology.
Huge congratulations to @craigmcrews.bsky.social on being awarded the #Havinga medal at the #Reedijk Symposium of the Leiden Institute of Chemistry for his groundbreaking work on induced proximity, including targeted protein degradation, as a new paradigm for #DrugDiscovery.
#ChemSky #ChemBio #TPD
#ChemSky #ChemBio #TPD
November 7, 2025 at 10:20 AM
Huge congratulations to @craigmcrews.bsky.social on being awarded the #Havinga medal at the #Reedijk Symposium of the Leiden Institute of Chemistry for his groundbreaking work on induced proximity, including targeted protein degradation, as a new paradigm for #DrugDiscovery.
#ChemSky #ChemBio #TPD
#ChemSky #ChemBio #TPD
Kim Bonger (@kimmb1.bsky.social) represents our @led3hub.bsky.social at the #Reedijk Symposium of the Leiden Institute of Chemistry with a great talk on "Chemical tools for profiling protein activity and cell targeting in (auto)immune disease".
#ChemBio #ChemSky #DrugDiscovery #FluorescenceFriday
#ChemBio #ChemSky #DrugDiscovery #FluorescenceFriday
November 7, 2025 at 9:00 AM
Kim Bonger (@kimmb1.bsky.social) represents our @led3hub.bsky.social at the #Reedijk Symposium of the Leiden Institute of Chemistry with a great talk on "Chemical tools for profiling protein activity and cell targeting in (auto)immune disease".
#ChemBio #ChemSky #DrugDiscovery #FluorescenceFriday
#ChemBio #ChemSky #DrugDiscovery #FluorescenceFriday
We are very happy that Nicolas Winssinger visited us today for a LED3 Lecture. He talked about his group's research into using functional nucleic acid assemblies for various applications including highly selective protein inhibitors and targeted photodynamic therapy.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
October 30, 2025 at 3:28 PM
We are very happy that Nicolas Winssinger visited us today for a LED3 Lecture. He talked about his group's research into using functional nucleic acid assemblies for various applications including highly selective protein inhibitors and targeted photodynamic therapy.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
We are looking forward to the LED3 Lecture of Nicolas Winssinger on Thursday October 30th: "Programing responsive assemblies from PNA-encoded and folded peptides"
If you are interested, make sure to come by!
www.universiteitleiden.nl/en/science/l...
#ChemBio #Chemistry #DrugDiscovery
If you are interested, make sure to come by!
www.universiteitleiden.nl/en/science/l...
#ChemBio #Chemistry #DrugDiscovery
October 29, 2025 at 11:56 AM
We are looking forward to the LED3 Lecture of Nicolas Winssinger on Thursday October 30th: "Programing responsive assemblies from PNA-encoded and folded peptides"
If you are interested, make sure to come by!
www.universiteitleiden.nl/en/science/l...
#ChemBio #Chemistry #DrugDiscovery
If you are interested, make sure to come by!
www.universiteitleiden.nl/en/science/l...
#ChemBio #Chemistry #DrugDiscovery
We are looking forward to the LED3 Lecture of Nicolas Winssinger on Thursday October 30th: "Programing responsive assemblies from PNA-encoded and folded peptides"
If you are interested, make sure to come by! www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky #DrugDiscovery
If you are interested, make sure to come by! www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky #DrugDiscovery
October 25, 2025 at 7:06 AM
We are looking forward to the LED3 Lecture of Nicolas Winssinger on Thursday October 30th: "Programing responsive assemblies from PNA-encoded and folded peptides"
If you are interested, make sure to come by! www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky #DrugDiscovery
If you are interested, make sure to come by! www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky #DrugDiscovery
On November 11th, Ilze Bot will present her exciting research in our LED3hub at the @leidenscience.bsky.social Tuesday Talks to the Faculty. She will talk about "Breaking the Cycle of Heart Attacks".
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
October 17, 2025 at 10:08 AM
On November 11th, Ilze Bot will present her exciting research in our LED3hub at the @leidenscience.bsky.social Tuesday Talks to the Faculty. She will talk about "Breaking the Cycle of Heart Attacks".
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
Great talk by Kim Bonger (@kimmb1.bsky.social) at our Faculty's (@leidenscience.bsky.social) Tuesday Talks. She talked about her group's exciting research into precision medicine with a special focus on autoimmune diseases.
#ChemBio #ChemSky #DrugDiscovery
#ChemBio #ChemSky #DrugDiscovery
October 14, 2025 at 2:28 PM
Great talk by Kim Bonger (@kimmb1.bsky.social) at our Faculty's (@leidenscience.bsky.social) Tuesday Talks. She talked about her group's exciting research into precision medicine with a special focus on autoimmune diseases.
#ChemBio #ChemSky #DrugDiscovery
#ChemBio #ChemSky #DrugDiscovery
How could #antibiotic research look like in the future? How can antibiotic development be made more economically rewarding?
Check out the interview with LED3 hub researcher @gillesvanwezel.bsky.social (Dutch only).
www.sciencelink.net/verdieping/p...
#ChemSky #ChemBio #DrugDiscovery
Check out the interview with LED3 hub researcher @gillesvanwezel.bsky.social (Dutch only).
www.sciencelink.net/verdieping/p...
#ChemSky #ChemBio #DrugDiscovery
October 11, 2025 at 8:52 AM
How could #antibiotic research look like in the future? How can antibiotic development be made more economically rewarding?
Check out the interview with LED3 hub researcher @gillesvanwezel.bsky.social (Dutch only).
www.sciencelink.net/verdieping/p...
#ChemSky #ChemBio #DrugDiscovery
Check out the interview with LED3 hub researcher @gillesvanwezel.bsky.social (Dutch only).
www.sciencelink.net/verdieping/p...
#ChemSky #ChemBio #DrugDiscovery
We are very happy that Tudor Oprea from Expert Systems Inc. visited us today for a talk. He talked about the use of Machine Learning and Artificial Intelligence in Drug Discovery.
October 7, 2025 at 2:57 PM
We are very happy that Tudor Oprea from Expert Systems Inc. visited us today for a talk. He talked about the use of Machine Learning and Artificial Intelligence in Drug Discovery.
We are very much looking forward to the LED3 Lecture by Nicolas Winssinger on Thursday, October 30th, at 4 p.m.
He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
October 7, 2025 at 1:20 PM
We are very much looking forward to the LED3 Lecture by Nicolas Winssinger on Thursday, October 30th, at 4 p.m.
He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
We are very happy that Alex Bullock from the University of Oxford (@ox.ac.uk) visited us today for a very well attended lecture. He talked about his group's work on making new E3 ligases available for degrader development using PROTACs and molecular glues. www.nature.com/articles/s41...
October 1, 2025 at 8:24 AM
We are very happy that Alex Bullock from the University of Oxford (@ox.ac.uk) visited us today for a very well attended lecture. He talked about his group's work on making new E3 ligases available for degrader development using PROTACs and molecular glues. www.nature.com/articles/s41...
We were very excited that Willem Velema visited us today for a great LED3hub Lecture. He talked about his group's diverse research projects on better understanding the structure of RNA motives and their ligandability with small molecules using techniques such as affinity-based profiling.
September 25, 2025 at 2:54 PM
We were very excited that Willem Velema visited us today for a great LED3hub Lecture. He talked about his group's diverse research projects on better understanding the structure of RNA motives and their ligandability with small molecules using techniques such as affinity-based profiling.
Do not miss this week's LED3 Lecture by Willem Velema!
www.universiteitleiden.nl/en/science/l...
www.universiteitleiden.nl/en/science/l...
September 24, 2025 at 2:14 PM
Do not miss this week's LED3 Lecture by Willem Velema!
www.universiteitleiden.nl/en/science/l...
www.universiteitleiden.nl/en/science/l...
On October 14th, Kim Bonger (@kimmb1.bsky.social) will present her exciting research in our LED3hub at the @leidenscience.bsky.social Tuesday Talks to the Faculty.
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
September 24, 2025 at 2:11 PM
On October 14th, Kim Bonger (@kimmb1.bsky.social) will present her exciting research in our LED3hub at the @leidenscience.bsky.social Tuesday Talks to the Faculty.
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...
We are very much looking forward to the first LED3 Lecture of the academic year on Thursday, September 25th, at 4 p.m.
Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
September 21, 2025 at 3:04 PM
We are very much looking forward to the first LED3 Lecture of the academic year on Thursday, September 25th, at 4 p.m.
Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.
www.universiteitleiden.nl/en/science/l...
#ChemSky #ChemBio #DrugDiscovery
We are very much looking forward to the LED3 Lectures 2025/2026. Already mark your calendars!
lnkd.in/e2GEibqP
Our speakers are:
Willem Velema
Nicolas Winssinger
Lotte Bjerre Knudsen
Anne Osbourn
Christina Woo
Thomas Clairfeuille
Peng Chen
Jon Stokes
@madelonmaurice.bsky.social
lnkd.in/e2GEibqP
Our speakers are:
Willem Velema
Nicolas Winssinger
Lotte Bjerre Knudsen
Anne Osbourn
Christina Woo
Thomas Clairfeuille
Peng Chen
Jon Stokes
@madelonmaurice.bsky.social
September 4, 2025 at 2:00 PM
We are very much looking forward to the LED3 Lectures 2025/2026. Already mark your calendars!
lnkd.in/e2GEibqP
Our speakers are:
Willem Velema
Nicolas Winssinger
Lotte Bjerre Knudsen
Anne Osbourn
Christina Woo
Thomas Clairfeuille
Peng Chen
Jon Stokes
@madelonmaurice.bsky.social
lnkd.in/e2GEibqP
Our speakers are:
Willem Velema
Nicolas Winssinger
Lotte Bjerre Knudsen
Anne Osbourn
Christina Woo
Thomas Clairfeuille
Peng Chen
Jon Stokes
@madelonmaurice.bsky.social
A great mini symposium on #cancer research today at @leidenscience.bsky.social organized by the #MCBIM department of Sylvestre Bonnet.
Petra Heffeter and Guy Ron talked about diverse aspects of cancer #diagnosis and #treatment.
#ChemSky #ChemBio #DrugDiscovery
Petra Heffeter and Guy Ron talked about diverse aspects of cancer #diagnosis and #treatment.
#ChemSky #ChemBio #DrugDiscovery
August 28, 2025 at 10:02 AM
A great mini symposium on #cancer research today at @leidenscience.bsky.social organized by the #MCBIM department of Sylvestre Bonnet.
Petra Heffeter and Guy Ron talked about diverse aspects of cancer #diagnosis and #treatment.
#ChemSky #ChemBio #DrugDiscovery
Petra Heffeter and Guy Ron talked about diverse aspects of cancer #diagnosis and #treatment.
#ChemSky #ChemBio #DrugDiscovery
We look forward to the LED3 Lecture by @madelonmaurice.bsky.social on June 25th, 2026. She will talk about her group's research on understanding patient-specific disease mechanisms to develop improved cancer-targeting strategies.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
August 28, 2025 at 9:37 AM
We look forward to the LED3 Lecture by @madelonmaurice.bsky.social on June 25th, 2026. She will talk about her group's research on understanding patient-specific disease mechanisms to develop improved cancer-targeting strategies.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
We look forward to the LED3 Lecture by Jon Stokes on May 28th, 2026. He will talk about his group's exciting research into using #ArtificialIntelligence for drug discovery in the field of #antibiotics.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
August 21, 2025 at 11:31 AM
We look forward to the LED3 Lecture by Jon Stokes on May 28th, 2026. He will talk about his group's exciting research into using #ArtificialIntelligence for drug discovery in the field of #antibiotics.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
We look forward to the LED3 Lecture by Peng Chen on April 23rd, 2026. His group performs research on bioorthogonal chemical reactions in living systems to provide innovative tools for life science research.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
August 14, 2025 at 9:25 AM
We look forward to the LED3 Lecture by Peng Chen on April 23rd, 2026. His group performs research on bioorthogonal chemical reactions in living systems to provide innovative tools for life science research.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
We look forward to the LED3 Lecture by Thomas Clairfeuille from Roche on March 26th, 2026. He will talk about the development of novel #antibiotics active against priority Gram-negative #bacteria. www.nature.com/artic...
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
August 7, 2025 at 1:10 PM
We look forward to the LED3 Lecture by Thomas Clairfeuille from Roche on March 26th, 2026. He will talk about the development of novel #antibiotics active against priority Gram-negative #bacteria. www.nature.com/artic...
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
We look forward to the LED3 Lecture by Christina Woo (@thewoolab.bsky.social) on February 26th, 2026. Her group performs exciting research in the field of #ChemBio and #ChemicalProteomics to understand small molecule activity in the proteome.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
July 31, 2025 at 3:48 PM
We look forward to the LED3 Lecture by Christina Woo (@thewoolab.bsky.social) on February 26th, 2026. Her group performs exciting research in the field of #ChemBio and #ChemicalProteomics to understand small molecule activity in the proteome.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
We look forward to the LED3 Lecture by Anne Osbourn on January 29th, 2026. Her group performs exciting research on plant natural products and their production for drug and chemical discovery programs.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...
July 24, 2025 at 1:16 PM
We look forward to the LED3 Lecture by Anne Osbourn on January 29th, 2026. Her group performs exciting research on plant natural products and their production for drug and chemical discovery programs.
Already mark your calendars! www.universiteitleid...
Already mark your calendars! www.universiteitleid...