@lea-dietrich.bsky.social
Reposted
Check out our new preprint on an integrated pipeline combining in situ #cryo-ET with MALDI #MSImaging for single-cell identification and classification from previously analysed EM-grids.
Link: www.biorxiv.org/content/10.1...
Link: www.biorxiv.org/content/10.1...
September 19, 2025 at 6:07 PM
Check out our new preprint on an integrated pipeline combining in situ #cryo-ET with MALDI #MSImaging for single-cell identification and classification from previously analysed EM-grids.
Link: www.biorxiv.org/content/10.1...
Link: www.biorxiv.org/content/10.1...
Reposted
Really proud of our most recently published work 😊 another installment in the story of the most incredible protein out there: the TOM complex 💜 #powerhouseofthecell Thanks @ahmed-noor-agip.bsky.social for the legendary team work and @lea-dietrich.bsky.social for all the support 💕 #teamCRYO
🔬 Check out our new article on the mitochondrial TOM complex! Researchers from the Structural Biology Department have resolved a high-resolution structure of the main entry point for proteins into mitochondria. 🚪 🤩
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Visualizing the Main Gate into Mitochondria
www.biophys.mpg.de
July 22, 2025 at 8:05 PM
Really proud of our most recently published work 😊 another installment in the story of the most incredible protein out there: the TOM complex 💜 #powerhouseofthecell Thanks @ahmed-noor-agip.bsky.social for the legendary team work and @lea-dietrich.bsky.social for all the support 💕 #teamCRYO
I'm still amazed to see this! Big thank you to Werner Kühlbrandt, Martin Beck and @erin-schuman.bsky.social for all their support and mentorship! I can't wait to get started on the exciting research projects at the @mpibrain.bsky.social ! 🧬🧠❄️🔬
July 3, 2025 at 5:37 AM
I'm still amazed to see this! Big thank you to Werner Kühlbrandt, Martin Beck and @erin-schuman.bsky.social for all their support and mentorship! I can't wait to get started on the exciting research projects at the @mpibrain.bsky.social ! 🧬🧠❄️🔬
Reposted
Big congratulations to Dr. Lea Dietrich @lea-dietrich.bsky.social for receiving the Otto Hahn Medal from the @maxplanck.de for her research on mitochondrial architecture! 🏅 A brilliant young scientist and a great role model 💪
July 2, 2025 at 9:55 AM
Big congratulations to Dr. Lea Dietrich @lea-dietrich.bsky.social for receiving the Otto Hahn Medal from the @maxplanck.de for her research on mitochondrial architecture! 🏅 A brilliant young scientist and a great role model 💪
Reposted
After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
June 27, 2025 at 10:58 AM
After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
June 15, 2025 at 12:23 PM
It's TOM season!! 😄 🥳 🎉 🔬❄️ What a perfect way to start the week after the easter weekend! Congrats to @ahmed-noor-agip.bsky.social , @pamornelas.bsky.social and colleagues! Fingers crossed! 🤞🤞
Please enjoy our (@pamornelas.bsky.social and I) work on the cryoEM structures of TOM from Chaetomium thermophilum, revealing insights into the early stages of preprotein translocation. The paper is still under review, so fingers crossed 🤞. www.biorxiv.org/content/10.1... @mpibp.bsky.social
Structures of Chaetomium thermophilum TOM complexes with bound preproteins
Mitochondria import most of their proteins from the cytoplasm through the TOM complex. Preproteins containing targeting signals are recognized by the TOM receptor subunits, and translocated by Tom40 a...
www.biorxiv.org
April 22, 2025 at 8:06 AM
It's TOM season!! 😄 🥳 🎉 🔬❄️ What a perfect way to start the week after the easter weekend! Congrats to @ahmed-noor-agip.bsky.social , @pamornelas.bsky.social and colleagues! Fingers crossed! 🤞🤞
Happy at the finish line of the Leipzig Marathon! Many thanks to @andschwarz.bsky.social , the people of leipzig and my mitochondria. Couldn't have done it without you! What a blast! ☺️🏃🏻♀️💨🏅 Many thanks to @pamornelas.bsky.social for the ATP synthase print! 🩵
April 13, 2025 at 4:29 PM
Happy at the finish line of the Leipzig Marathon! Many thanks to @andschwarz.bsky.social , the people of leipzig and my mitochondria. Couldn't have done it without you! What a blast! ☺️🏃🏻♀️💨🏅 Many thanks to @pamornelas.bsky.social for the ATP synthase print! 🩵
Reposted
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social
@wehi-research.bsky.social @komanderlab.bsky.social
March 13, 2025 at 7:20 PM
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
@wehi-research.bsky.social @komanderlab.bsky.social
@wehi-research.bsky.social @komanderlab.bsky.social
Yeahi, congrats Jana!! ❄️🔬🐁🧪👩🏻🔬
Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1...
We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
February 13, 2025 at 6:15 PM
Yeahi, congrats Jana!! ❄️🔬🐁🧪👩🏻🔬
