Lars Bock
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larsvbock.bsky.social
Lars Bock
@larsvbock.bsky.social
Theoretical and computational physicist working on ribosomes and antibiotics - atomistic simulations, statistical physics and ML. Project leader at the MPI for Multidisciplinary Sciences
https://t.co/1ecLGaOjXB 🚴
Reposted by Lars Bock
📜 New preprint! We developed PoGö, an algorithm to optimize the essential dynamics of GöMartini proteins based on all-atom simulations: www.biorxiv.org/content/10.1...
October 27, 2025 at 7:54 AM
Reposted by Lars Bock
Awesome to see this epic piece of work, led by @cecclementi.bsky.social, finally appear in @natchem.nature.com.

The development of a general coarse-grained protein forcefield to describe folding, binding and conformation changes without solvent and all-atom, has been long anticipated!
July 18, 2025 at 11:25 AM
Reposted by Lars Bock
🐦 For the early birds and #ribosome #MD and #ML enthusiasts #EBSA2025: Don't miss 📌 Lars' @larsvbock.bsky.social oral presentation (O-16.1) tomorrow at 8:30 during session 16 in hall 1: "Combining #Simulations and Machine Learning with Experiments to Explore Ribosomal #Translation" 🔗 t1p.de/ccmwk
Dynamics and Energetics of Ribosomal Translation
www.mpinat.mpg.de
July 3, 2025 at 1:04 PM
Reposted by Lars Bock
One day remaining before this closes!
bsky.app/profile/benj...
My lab, at Karolinska, in Stockholm, is looking for a PhD student with a computational/quantitative background to work on probabilistic/generative models of proteins (structure and sequence). The research will involve methods development, and applications in vaccine design.
June 21, 2025 at 4:45 AM
Reposted by Lars Bock
🆕📣 Job alert: Our department @compbiophys.bsky.social is looking for a PhD student or Postdoc specializing in theory and methods for non-equilibrium theory and atomistic simulations of complex biomolecules.
More information here: ⬇️
💭 Would you like to contribute to projects in the field of "Theory and Methods for Non-equilibrium #Theory and Atomistic Simulations of Complex# Biomolecules"? Join our department as #PhD student or #Postdoc at @mpi-nat.bsky.social in 🇩🇪 🔗 Here are more details www.mpinat.mpg.de/4965656/10-2... #job
April 7, 2025 at 11:55 AM
Reposted by Lars Bock
💭 Would you like to contribute to projects in the field of "Theory and Methods for Non-equilibrium #Theory and Atomistic Simulations of Complex# Biomolecules"? Join our department as #PhD student or #Postdoc at @mpi-nat.bsky.social in 🇩🇪 🔗 Here are more details www.mpinat.mpg.de/4965656/10-2... #job
April 1, 2025 at 1:11 PM
Reposted by Lars Bock
Excited to share my latest research. In this paper in PNAS, I use #cryoEM and #crystallography to solve multiple new structures of a viral RNA motif that controls frameshifting.

#virus #retrovirus #structuralbiology #science #biochemistry

www.pnas.org/doi/10.1073/...
Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus–programmed ribosomal frameshifting element | PNAS
A hallmark of retrovirus replication is the translation of two different polyproteins from one RNA through programmed –1 frameshifting. This is a m...
www.pnas.org
April 2, 2025 at 4:36 PM
Reposted by Lars Bock
🧐 Are you a computational physicist and expert in probability theory? 👉 Contribute to our project "Theory and Algorithms for Structure Determination from Single Molecule X-Ray Scattering Images" as PhD student or Postdoc! 🔗 Check our job advert for more details www.mpinat.mpg.de/4988122/09-2...
April 1, 2025 at 1:01 PM
Reposted by Lars Bock
Gemma Solomon and I are looking for a postdoc to work across the two groups on modelling biological systems with a view to applications for quantum computing

More details about the project including how to apply in the link below. Deadline April 9 2025

candidate.hr-manager.net/ApplicationI...
March 22, 2025 at 7:16 PM
Reposted by Lars Bock
I need y'all to sit with this headline and understand what is being done to our community. They're trying to criminalize our very existence.

This is a campaign of eradication.

www.nbcnews.com/nbc-out/rcna...
March 10, 2025 at 7:32 PM
Reposted by Lars Bock
There was a lot of #AcademicFreedom, good scholarship, and independent thought in German universities before Hitler. After Hitler had risen to power, many academics fled the country. Some resisted the Nazi regime and were persecuted. Most adapted to a new situation. Here are some examples. 1/n
January 20, 2025 at 5:26 AM
Reposted by Lars Bock
A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.”
Absurd we still need to go through this
🧪👩‍🔬
March 6, 2025 at 4:40 PM
Reposted by Lars Bock
🥹 Last day at #bps2025 and a 🤩 final poster session with contributions from our group @compbiophys.bsky.social @mpi-nat.bsky.social: Meet Annke, Lars @larsvbock.bsky.social and Malte during today's session 10:30 AM -12:30 PM and discuss their exciting projects with them before you say goodbye...👋
February 19, 2025 at 7:52 AM
Reposted by Lars Bock
🚨The triennial Ribosome Conference will be held June 22-June 27, 2025 in Pacific Grove, California. Registration is open - hope to see many #Ribosome #RNA aficionados there. #RNASky #AcademicSky 🧪 rna.ucsc.edu/rnacenter/ri...
Ribosomes2025 Program
The Ribosome Conference is held every three years and brings together researchers working on all aspects of the ribosome, from structure and function to its role in disease and use as a drug target.
rna.ucsc.edu
February 18, 2025 at 12:15 AM
Reposted by Lars Bock
We are hiring a Flatiron Research Fellow in the Structural Molecular Biophysics team! Experience with cryoEM and/or membrane protein simulations are a plus! Happy to chat in person with anyone at #bps2025 ! apply.interfolio.com/160227
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
February 17, 2025 at 1:55 AM
Reposted by Lars Bock
We proudly present a selection of research projects from @compbiophys.bsky.social at this year's #bps2025 meeting in LA! Don't miss the oral presentations or posters being presented and find us in the program biophysics.cld.bz/BPS2025-Full...
February 14, 2025 at 2:09 PM
Reposted by Lars Bock
Recharging batteries in Sta Monica with @compbiophys.bsky.social. Come and reach us in #bps2025! (Contributions listed in the comments)

@reinierdevries.bsky.social
@larsvbock.bsky.social
@steschuu.bsky.social @oberend.bsky.social
February 15, 2025 at 2:59 AM
Reposted by Lars Bock
If you are interested in postdoctoral research on ligand-gated ion channels and the synapse, or simulation/AI methods for structural biology - drop me a line if you'll be around at Biophysical Society in LA! #bps2025 #bps #biophysics
February 14, 2025 at 5:50 AM
Reposted by Lars Bock
📢 Out now: Our double feature “Constant pH #cpH Simulation with #FMM Electrostatics in #GROMACS#openaccess in #JCTC on 🅰️ Design and Applications and 🅱️ GPU Accelerated Hamiltonian Interpolation #HI! 👇 Happy simulating! ☺️
February 13, 2025 at 2:47 PM
Reposted by Lars Bock
The regular registration for on-site participation has been closed. However, it is still possible to join our workshop online! You find the link to the according registration on our workshop website 🔗https://www.mpinat.mpg.de/workshop/huenfeld #TheoryHünfeld2025 #biophysics
📢 It's our great pleasure to invite you all to our upcoming #Workshop on "Computer Simulation and #Theory of Macromolecules" in #Hünfeld on March 7-8, 2025 in #hybrid format! See you online or on-site! More details are provided here: www.mpinat.mpg.de/workshop/hue... #TheoryHünfeld2025 #biophysics
January 7, 2025 at 9:55 AM
Reposted by Lars Bock
Join us in beautiful Prague to study molecular physics. My group is offering a PhD position at UCT Prague, Czechia related to #protein - #RNA interactions. For more details, visit mhko.science/p/positions/ or contact us directly at positions@mhko.science.
January 26, 2025 at 8:36 PM
Reposted by Lars Bock
Over 60 German unis and institutes jointly announce they're leaving X due to the "lack of compatibility between the platform and the institutions' core values" (my translation)
nachrichten.idw-online.de/2025/01/10/h...
Was verbindet diese beeindruckende Vielzahl deutscher Hochschulen und Universitäten? Sie haben heute gemeinsam bekannt gegeben, dass sie sich von Elon Musks Plattform X (ehemals Twitter) zurückziehen. Möge der Rest dem guten Beispiel folgen. Es ist an der Zeit.
January 10, 2025 at 10:03 AM
Reposted by Lars Bock
Microscopy Nodes is now up on bioRxiv! 🚀

This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev).

High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬

www.biorxiv.org/content/10.1...
January 15, 2025 at 1:39 PM
Reposted by Lars Bock
Are you interested in exploring RNA with cutting-edge techniques in a dynamic, collaborative and international environment? Just click below to learn more or send me a message. We will be happy to connect and discuss this further!

Dear Colleagues in the RNA field, please RT and spread the word :)
January 11, 2025 at 2:17 PM