Laeth George, MD
@laethgeorge.bsky.social
Husband and Girl Dad, Hematologist/Oncologist, avid reader, mediocre golfer, and supporter of disappointing sports teams. Views my own. #MedSky #OncSky
Reposted by Laeth George, MD
After leukemia treatments failed, Alyssa Tapley, at age 13, was told she would die. Then, doctors tried an experimental gene-edited therapy. She became the first human to try the treatment made possible by U.S. federal funding. Now 16, she’s cancer-free and planning her future.
November 10, 2025 at 12:33 AM
After leukemia treatments failed, Alyssa Tapley, at age 13, was told she would die. Then, doctors tried an experimental gene-edited therapy. She became the first human to try the treatment made possible by U.S. federal funding. Now 16, she’s cancer-free and planning her future.
Reposted by Laeth George, MD
Surrogate pregnancies are increasingly popular in tech circles, and the practice is expected to explode globally in the coming decade. It’s also shockingly unregulated. This is a story about what happens when it goes horribly wrong.
The Baby Died. Whose Fault Is It?
When her son died in utero, a venture capitalist went to extremes to punish her surrogate.
wrd.cm
September 6, 2025 at 7:08 PM
Surrogate pregnancies are increasingly popular in tech circles, and the practice is expected to explode globally in the coming decade. It’s also shockingly unregulated. This is a story about what happens when it goes horribly wrong.
Data from #ASCO25 showed that Medicaid expansion was associated with improved survival for patients with newly diagnosed cancer. It doesn’t matter what advancements we make if access to care is denied.
@physiciandemocracy.medsky.social @ascocancer.bsky.social
ascopubs.org/doi/10.1200/...
@physiciandemocracy.medsky.social @ascocancer.bsky.social
ascopubs.org/doi/10.1200/...
June 4, 2025 at 1:52 PM
Data from #ASCO25 showed that Medicaid expansion was associated with improved survival for patients with newly diagnosed cancer. It doesn’t matter what advancements we make if access to care is denied.
@physiciandemocracy.medsky.social @ascocancer.bsky.social
ascopubs.org/doi/10.1200/...
@physiciandemocracy.medsky.social @ascocancer.bsky.social
ascopubs.org/doi/10.1200/...
Reposted by Laeth George, MD
In 2023, the U.S. spent approximately $1.35 trillion on healthcare administration. That’s more than we spent on:
•Physician salaries (~$350B)
•Nursing salaries (~$335B)
•Retail prescription drugs (~$450B)
•Imaging, lab tests, EHRs, and outpatient procedures combined
#BlueSky #MedSky #NurseSky
•Physician salaries (~$350B)
•Nursing salaries (~$335B)
•Retail prescription drugs (~$450B)
•Imaging, lab tests, EHRs, and outpatient procedures combined
#BlueSky #MedSky #NurseSky
May 17, 2025 at 6:44 PM
Interesting data answering an important question—the role of cytoreductive nephrectomy with modern IO-TKI based treatments. In this pooled analysis from 5 trials, CN associated with OS benefit of 46 vs 28 months (HR 0.63, 95% CI 0.51-0.77).
#oncsky #oncology #rcc
academic.oup.com/jnci/article...
#oncsky #oncology #rcc
academic.oup.com/jnci/article...
Cytoreductive nephrectomy in the era of immune checkpoint inhibitors: a US Food and Drug Administration pooled analysis
AbstractBackground. This pooled analysis of patient-level data from trials evaluated the clinical outcomes of patients with metastatic renal cell carcinoma
academic.oup.com
May 15, 2025 at 1:57 PM
Interesting data answering an important question—the role of cytoreductive nephrectomy with modern IO-TKI based treatments. In this pooled analysis from 5 trials, CN associated with OS benefit of 46 vs 28 months (HR 0.63, 95% CI 0.51-0.77).
#oncsky #oncology #rcc
academic.oup.com/jnci/article...
#oncsky #oncology #rcc
academic.oup.com/jnci/article...
Reposted by Laeth George, MD
I want politics to be about a better everyday life.
Here's what that can look like:
Here's what that can look like:
April 24, 2025 at 7:20 PM
I want politics to be about a better everyday life.
Here's what that can look like:
Here's what that can look like:
Reposted by Laeth George, MD
Reposted by Laeth George, MD
This is Poppy. Her pink silk sleeping mask fell off right before bedtime. Fortunately she only threw a very reasonably sized tantrum about the ordeal. 13/10
March 5, 2025 at 11:24 PM
This is Poppy. Her pink silk sleeping mask fell off right before bedtime. Fortunately she only threw a very reasonably sized tantrum about the ordeal. 13/10
Reposted by Laeth George, MD
We've been saving this little pup for when we thought you all might really need a gold star. And, given the current circumstances, here she is. 13/10
March 5, 2025 at 7:00 PM
We've been saving this little pup for when we thought you all might really need a gold star. And, given the current circumstances, here she is. 13/10
I encourage all physicians and healthcare professionals to contact your Congressional reps and Senator Bill Cassidy—a fellow physician and who provided the crucial vote to confirm RFK jr, and is a prominent supporter of vaccines (like 99.99% of us).
www.cassidy.senate.gov/contact/get-...
www.cassidy.senate.gov/contact/get-...
February 27, 2025 at 6:02 PM
I encourage all physicians and healthcare professionals to contact your Congressional reps and Senator Bill Cassidy—a fellow physician and who provided the crucial vote to confirm RFK jr, and is a prominent supporter of vaccines (like 99.99% of us).
www.cassidy.senate.gov/contact/get-...
www.cassidy.senate.gov/contact/get-...
Reposted by Laeth George, MD
My trusted advisor has been emerging from the shadows a lot lately, wonder what that's about
February 27, 2025 at 2:22 AM
My trusted advisor has been emerging from the shadows a lot lately, wonder what that's about
Seems about ~1/3 of his state, Louisiana, is on Medicaid for their healthcare. I don’t think his constituent would take kindly to losing their health insurance.
REPORTER: Can you say unequivocally that down the line, there won't be cuts to Medicaid programs?
MIKE JOHNSON: Medicaid is hugely problematic because it has a lot of fraud, waste, and abuse.
MIKE JOHNSON: Medicaid is hugely problematic because it has a lot of fraud, waste, and abuse.
February 25, 2025 at 4:18 PM
Seems about ~1/3 of his state, Louisiana, is on Medicaid for their healthcare. I don’t think his constituent would take kindly to losing their health insurance.
Reposted by Laeth George, MD
February 23, 2025 at 7:57 PM
Reposted by Laeth George, MD
This is Buster. He's having the best day ever. Gets to play in the pool AND get rained on at the same time. 13/10 every lab's dream
February 20, 2025 at 11:47 PM
This is Buster. He's having the best day ever. Gets to play in the pool AND get rained on at the same time. 13/10 every lab's dream
Reposted by Laeth George, MD
Imagine being rich enough to do anything you want and choosing to take food and medicine from starving children to give yourself even more money.
February 18, 2025 at 11:06 PM
Imagine being rich enough to do anything you want and choosing to take food and medicine from starving children to give yourself even more money.
Reposted by Laeth George, MD
In Texas, 22 children and 2 adults have become ill with measles in a community where the vaccination rate among kindergartners is only 82%. Nine have been hospitalized so far and the outbreak continues to grow. The anti-vax movement harms children. Period. www.washingtonpost.com/health/2025/...
At least 22 children and two adults infected in Texas measles outbreak
Nine of those infected were hospitalized and more cases are likely, health authorities said. U.S. vaccination rates for measles are falling, according to the CDC.
www.washingtonpost.com
February 13, 2025 at 9:45 PM
In Texas, 22 children and 2 adults have become ill with measles in a community where the vaccination rate among kindergartners is only 82%. Nine have been hospitalized so far and the outbreak continues to grow. The anti-vax movement harms children. Period. www.washingtonpost.com/health/2025/...
Reposted by Laeth George, MD
We only know this man is in Gitmo because Noem tweeted a propaganda photo that included him and his sister saw it. He has no criminal record. He entered the US in January and immediately made an appointment with CBP to claim asylum. They sent him to a concentration camp bc of his basketball tattoo.
Venezuelan Migrant Sent to Guantánamo Bay Is ‘Not a Criminal,’ Family Pleads (Gift Article)
Luis Alberto Castillo arrived in the United States so that he could “give everything to his son,” said his sister. Then, while scrolling on TikTok, she found out he was headed to Guantánamo.
www.nytimes.com
February 12, 2025 at 4:09 PM
We only know this man is in Gitmo because Noem tweeted a propaganda photo that included him and his sister saw it. He has no criminal record. He entered the US in January and immediately made an appointment with CBP to claim asylum. They sent him to a concentration camp bc of his basketball tattoo.
Reposted by Laeth George, MD
Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...
Johns Hopkins sues federal government over NIH funds
Johns Hopkins University joined several universities in a lawsuit on Monday evening suing the federal government over NIH funding.
www.thebaltimorebanner.com
February 11, 2025 at 5:34 PM
Johns Hopkins officials said the NIH funding cut puts at risk approximately 600 current and ongoing clinical trials at Hopkins, including open clinical trials in cancer, pediatrics and children’s health, heart and vascular studies and the aging brain. www.thebaltimorebanner.com/education/hi...
Reposted by Laeth George, MD
Petition to Reverse the NIH Indirect Cost Cap.
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
This campaign needs you now
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
chng.it
February 10, 2025 at 3:38 PM
Petition to Reverse the NIH Indirect Cost Cap.
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Reposted by Laeth George, MD
When Elon was a kid, survival for ALL, the most common childhood cancer, was <10%
Now it’s >90% due to funded collaboratives (high indirect costs) whose work ultimately SAVES THOUSANDS OF LIVES EVERY YEAR.
For other cancers there’s still so much progress to be made.
I think it’s worth it.
Now it’s >90% due to funded collaboratives (high indirect costs) whose work ultimately SAVES THOUSANDS OF LIVES EVERY YEAR.
For other cancers there’s still so much progress to be made.
I think it’s worth it.
February 8, 2025 at 11:04 PM
When Elon was a kid, survival for ALL, the most common childhood cancer, was <10%
Now it’s >90% due to funded collaboratives (high indirect costs) whose work ultimately SAVES THOUSANDS OF LIVES EVERY YEAR.
For other cancers there’s still so much progress to be made.
I think it’s worth it.
Now it’s >90% due to funded collaboratives (high indirect costs) whose work ultimately SAVES THOUSANDS OF LIVES EVERY YEAR.
For other cancers there’s still so much progress to be made.
I think it’s worth it.
If rattles means threatens the entire American biomedical research system and promises to undermine our scientific capabilities for a generation (or more), then yeah, we’re rattled.
The National Institutes of Health has dramatically changed its grant-making terms by limiting how much it will disperse for costs such as equipment and administration.
NIH announces new funding policy that rattles medical researchers
The National Institutes of Health has dramatically changed its grant-making terms by limiting how much it will disperse for costs such as equipment and administration.
www.npr.org
February 8, 2025 at 7:54 PM
If rattles means threatens the entire American biomedical research system and promises to undermine our scientific capabilities for a generation (or more), then yeah, we’re rattled.
Reposted by Laeth George, MD
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
Reposted by Laeth George, MD
Reposted by Laeth George, MD
One of Elon Musk's DOGE staffers is a 19-year-old who goes by "Big Balls" online and owns a company called Tesla.Sexy that sells an AI bot for Russian Discord servers. These are the kinds of people who have access to the country's most sensitive data www.wired.com/story/edward...
DOGE Teen Owns ‘Tesla.Sexy LLC’ and Worked at Startup That Has Hired Convicted Hackers
Experts question whether Edward Coristine, a DOGE staffer who has gone by “Big Balls” online, would pass the background check typically required for access to sensitive US government systems.
www.wired.com
February 6, 2025 at 2:53 PM
One of Elon Musk's DOGE staffers is a 19-year-old who goes by "Big Balls" online and owns a company called Tesla.Sexy that sells an AI bot for Russian Discord servers. These are the kinds of people who have access to the country's most sensitive data www.wired.com/story/edward...
Reposted by Laeth George, MD
Every one of these guys thinks they’re Oppenheimer mixed with Andrew Carnegie and they own something called SplortDotCom that got bought by Boozoo
2025 will go down as the year when all the subtext became text
February 6, 2025 at 12:24 PM
Every one of these guys thinks they’re Oppenheimer mixed with Andrew Carnegie and they own something called SplortDotCom that got bought by Boozoo