Dariusz Jan Smolinski
@labdjsmolinski.bsky.social
Head of RNA bioimaging lab, Husband & Father-of-two;
Biomolecular Condensates, P-bodies, Cajal bodies, miRNA & snRNP maturation, mRNA nuclear retention, tennis
Biomolecular Condensates, P-bodies, Cajal bodies, miRNA & snRNP maturation, mRNA nuclear retention, tennis
Reposted by Dariusz Jan Smolinski
NASA poinformowała o śmierci Jima Lovella, amerykańskiego astronauty i dowódcy misji Apollo 13. Miał 97 lat. #Wyborcza #Apollo #NASA #kosmos #Księżyc wyborcza.pl/7,75400,3216...
Nie żyje Jim Lovell, dowódca Apollo 13
NASA poinformowała o śmierci Jima Lovella, amerykańskiego astronauty i dowódcy misji Apollo 13. Miał 97 lat.
wyborcza.pl
August 8, 2025 at 8:41 PM
Reposted by Dariusz Jan Smolinski
Researcher: "We let the data speak for itself."
Earlier that day:
Earlier that day:
January 2, 2025 at 3:31 PM
Researcher: "We let the data speak for itself."
Earlier that day:
Earlier that day:
Reposted by Dariusz Jan Smolinski
mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles to enable rapid release when transcription resumes @thedawsonlab.bsky.social
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
January 2, 2025 at 10:38 PM
Reposted by Dariusz Jan Smolinski
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
#RNAbiology #RNAlocalization
www.cell.com/molecular-ce...
#RNAbiology #RNAlocalization
www.cell.com/molecular-ce...
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.
www.cell.com
January 2, 2025 at 11:49 PM
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
#RNAbiology #RNAlocalization
www.cell.com/molecular-ce...
#RNAbiology #RNAlocalization
www.cell.com/molecular-ce...
Reposted by Dariusz Jan Smolinski
Colleagues on X quote-tweeting Musk et al. to explain how they're wrong
a man is standing on a sandy beach looking at the ocean
ALT: a man is standing on a sandy beach looking at the ocean
media.tenor.com
December 28, 2024 at 1:54 PM
Colleagues on X quote-tweeting Musk et al. to explain how they're wrong
Reposted by Dariusz Jan Smolinski
A journal club on @lumasullo.bsky.social et al. RASTMIN paper (with explanations for non-microscopists audience) www.youtube.com/watch?v=ozKA...
Session 1 (Optical Physics): Think Like a Physicist—Clematis Training Program
YouTube video by Clematis Research Empowerment Hub
www.youtube.com
December 18, 2024 at 2:17 PM
A journal club on @lumasullo.bsky.social et al. RASTMIN paper (with explanations for non-microscopists audience) www.youtube.com/watch?v=ozKA...
Reposted by Dariusz Jan Smolinski
ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY.
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Ångström-resolution fluorescence microscopy - Nature
The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off...
www.nature.com
November 27, 2024 at 9:47 AM
ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY.
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Reposted by Dariusz Jan Smolinski
Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body https://www.biorxiv.org/content/10.1101/2024.11.28.625872v1
Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body https://www.biorxiv.org/content/10.1101/2024.11.28.625872v1
Small subcellular organelles orchestrate key cellular functions. How biomolecules are spatially orga
www.biorxiv.org
November 29, 2024 at 6:48 PM
Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body https://www.biorxiv.org/content/10.1101/2024.11.28.625872v1
We’ve just installed a new Abberior STED FACILITY LINE microscope at Nicolaus Copernicus University. Next week, we begin studying Cajal bodies, P-bodies, SG and other biomolecular condensates in post-transcriptional gene regulation. Thanks @ministerstwonauki.bsky.social for their financial support.
December 8, 2024 at 9:57 PM
We’ve just installed a new Abberior STED FACILITY LINE microscope at Nicolaus Copernicus University. Next week, we begin studying Cajal bodies, P-bodies, SG and other biomolecular condensates in post-transcriptional gene regulation. Thanks @ministerstwonauki.bsky.social for their financial support.