kiki 🏳️‍⚧️🏳️‍🌈🧬
banner
kiki-omics.bsky.social
kiki 🏳️‍⚧️🏳️‍🌈🧬
@kiki-omics.bsky.social
she/they

Lecturer in human genetics at
@exeter.ac.uk | Previously at @ox.ac.uk & @sangerinstitute.bsky.social | Proudly autistic & trans | Latinx

https://experts.exeter.ac.uk/45188-kiki-canogamez
Pinned
Our study on cfDNA & sepsis is now out in Cell Genomics @cellpress.bsky.social 🥳💙

We measure cfDNA features using NGS and show that cfDNA accumulates in the blood during sepsis, likely because the liver cannot properly clear it.

This study was led by @ndm.ox.ac.uk

Available at: bit.ly/4oEv6wP
🎓 Fully funded PhD at University of Exeter & University of Bath!
Work on lupus research using genomics, liquid biopsies & AI.
Open to UK + international students.

📧 If interested, please reach out to me by email
📅 Apply by Oct 20 👉 gw4biomed.ac.uk

#PhD #Genomics #AI #Bioinformatics
GW4 BioMed MRC DTP - GW4 BioMed MRC DTP
The GW4 BioMed MRC Doctoral Training Partnership is a collaboration between Bath, Bristol, Cardiff and Exeter Universities.
gw4biomed.ac.uk
September 2, 2025 at 3:43 PM
A lovely editorial on our most recent study, which shows a build-up of DNA in the circulation of patients with severe infections ❤️

www.ndm.ox.ac.uk/news/study-r...

You can also find the full study at: bit.ly/4oEv6wP
Study reveals liver problems may drive DNA build-up in sepsis patients
Researchers at NDM’s Centre for Human Genetics have discovered that cell-free DNA builds up in the blood of patients with sepsis because of impaired liver clearance. These findings show that investiga...
www.ndm.ox.ac.uk
August 12, 2025 at 11:12 AM
Our study on cfDNA & sepsis is now out in Cell Genomics @cellpress.bsky.social 🥳💙

We measure cfDNA features using NGS and show that cfDNA accumulates in the blood during sepsis, likely because the liver cannot properly clear it.

This study was led by @ndm.ox.ac.uk

Available at: bit.ly/4oEv6wP
August 12, 2025 at 11:09 AM
Reposted by kiki 🏳️‍⚧️🏳️‍🌈🧬
Nature research paper: Clonal tracing with somatic epimutations reveals dynamics of blood ageing

https://go.nature.com/43NOe1R
Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature
The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.
go.nature.com
May 21, 2025 at 5:52 PM
Super excited to introduce our new study, now available as a preprint: tinyurl.com/2hv97yb4

We profiled circulating cell-free DNA during sepsis to understand why it increases >40-fold during disease. We assess cfDNA methylomes, fragmentomes, and nucleosome footprints.

(1/3)
February 21, 2025 at 1:30 PM
Reposted by kiki 🏳️‍⚧️🏳️‍🌈🧬
The circulating cell-free DNA landscape in sepsis is dominated by impaired liver clearance https://www.biorxiv.org/content/10.1101/2025.02.17.638622v1
February 21, 2025 at 7:37 AM
Reposted by kiki 🏳️‍⚧️🏳️‍🌈🧬
A Review in Nature Reviews Genetics examines computational and statistical challenges that must be addressed for the rigorous construction of interpretable epigenetic clocks at cell-type and single-cell resolution. https://go.nature.com/3EKFgt0 🔒
February 15, 2025 at 8:21 PM
Reposted by kiki 🏳️‍⚧️🏳️‍🌈🧬
Today is the #InternationalDayOfWomenAndGirlsInScience! So to celebrate, we'd like to share the words of three inspiring #WomenInScience here at NDM. Discover the advice they'd give to themselves when they started their career in STEM 👩‍🔬🧪🥼
February 11, 2025 at 9:00 AM