June 23, 2025 at 12:28 PM
Reposted by Shreyank Tripathi
The ASIs have arrived
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension | NEJM
Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this mult...
www.nejm.org
April 23, 2025 at 10:01 PM
The ASIs have arrived
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
www.nejm.org/doi/full/10....
Aldosterone synthase inhibitors - first one to finish the phase 3 line
#Lorundrostat #Hypertension
Reposted by Shreyank Tripathi
In all fairness, your average value based care program is based on equally questionable formulas.
April 3, 2025 at 10:08 PM
In all fairness, your average value based care program is based on equally questionable formulas.
Reposted by Shreyank Tripathi
Retatrutide (GLP, GIP, Glucagon receptor agonist) and albuminuria and GFR changes from phase 2 trial now in @kireports.bsky.social
Two Ph2 trials, one in T2DM and another in Obesity with about N ~ 300 each
uACR reduced in both RCTs (A, B)
Much more pronounced when baseline > 30 mg/g (C, D)
1/
Two Ph2 trials, one in T2DM and another in Obesity with about N ~ 300 each
uACR reduced in both RCTs (A, B)
Much more pronounced when baseline > 30 mg/g (C, D)
1/
April 3, 2025 at 9:30 PM
Retatrutide (GLP, GIP, Glucagon receptor agonist) and albuminuria and GFR changes from phase 2 trial now in @kireports.bsky.social
Two Ph2 trials, one in T2DM and another in Obesity with about N ~ 300 each
uACR reduced in both RCTs (A, B)
Much more pronounced when baseline > 30 mg/g (C, D)
1/
Two Ph2 trials, one in T2DM and another in Obesity with about N ~ 300 each
uACR reduced in both RCTs (A, B)
Much more pronounced when baseline > 30 mg/g (C, D)
1/
www.nature.com/articles/d41...
"Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia..."
"Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia..."
Could the shingles vaccine help to prevent dementia?
Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia — but it’s not yet clear how.
www.nature.com
April 4, 2025 at 1:53 AM
www.nature.com/articles/d41...
"Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia..."
"Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia..."
March 29, 2025 at 2:23 AM
www.jrnjournal.org/article/S105...
Low-PPR foods are important for CKD patients. Siggi's Coconut Mixed Berries had the lowest PPR, making it potentially the most desirable for CKD pt.Delicious Coconut Strawberry had the highest PPR, highlighting the importance of product selection for pt with CKD.
Low-PPR foods are important for CKD patients. Siggi's Coconut Mixed Berries had the lowest PPR, making it potentially the most desirable for CKD pt.Delicious Coconut Strawberry had the highest PPR, highlighting the importance of product selection for pt with CKD.
Phosphorus Content of Several Plant-Based Yogurts
In people with chronic kidney disease (CKD), hyperphosphatemia is a risk factor for
mortality. Though unproven, dietary phosphorus control is considered essential in
CKD. Although dietary and serum ph...
www.jrnjournal.org
March 27, 2025 at 8:49 PM
www.jrnjournal.org/article/S105...
Low-PPR foods are important for CKD patients. Siggi's Coconut Mixed Berries had the lowest PPR, making it potentially the most desirable for CKD pt.Delicious Coconut Strawberry had the highest PPR, highlighting the importance of product selection for pt with CKD.
Low-PPR foods are important for CKD patients. Siggi's Coconut Mixed Berries had the lowest PPR, making it potentially the most desirable for CKD pt.Delicious Coconut Strawberry had the highest PPR, highlighting the importance of product selection for pt with CKD.
academic.oup.com/ajh/article-...
The higher CRF levels may mitigate the trend of age-related rise in arterial stiffness in individuals with and without HTN or diabetes. However, this attenuating trend appears more pronounced in individuals without HTN or diabetes.
The higher CRF levels may mitigate the trend of age-related rise in arterial stiffness in individuals with and without HTN or diabetes. However, this attenuating trend appears more pronounced in individuals without HTN or diabetes.
Association Between Cardiorespiratory Fitness and Trend of Age-Related Rise in Arterial Stiffness in Individuals With and Without Hypertension or Diabetes
AbstractBACKGROUND. This study aimed to investigate whether higher cardiorespiratory fitness (CRF) can modify the trend of age-related rise in arterial sti
academic.oup.com
March 13, 2025 at 10:22 PM
academic.oup.com/ajh/article-...
The higher CRF levels may mitigate the trend of age-related rise in arterial stiffness in individuals with and without HTN or diabetes. However, this attenuating trend appears more pronounced in individuals without HTN or diabetes.
The higher CRF levels may mitigate the trend of age-related rise in arterial stiffness in individuals with and without HTN or diabetes. However, this attenuating trend appears more pronounced in individuals without HTN or diabetes.
Reposted by Shreyank Tripathi
There is a huge and vital Indian Nephrology community on social media but they have largely not made the jump to Bluesky. Please support Arvind and show him how good #NephSky is so he can encourage other Indians to migrate over. #WeAreBetterTogether
In 10 years, the prevalence of T2DM increased in younger (7.8% vs. 4.5%, p < 0.0001) and older individuals (34% vs. 28.4%, p < 0.0001).
In 10 yrs, incidence of T2DM increased by 120% & 150% in the younger & older individuals, respectively.
pmc.ncbi.nlm.nih.gov/articles/PMC...
@isn-india.bsky.social
In 10 yrs, incidence of T2DM increased by 120% & 150% in the younger & older individuals, respectively.
pmc.ncbi.nlm.nih.gov/articles/PMC...
@isn-india.bsky.social
February 19, 2025 at 2:47 PM
There is a huge and vital Indian Nephrology community on social media but they have largely not made the jump to Bluesky. Please support Arvind and show him how good #NephSky is so he can encourage other Indians to migrate over. #WeAreBetterTogether
Reposted by Shreyank Tripathi
Tacrolimus for kidney transplant patients only $30.36 for 5mg 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky
January 12, 2025 at 8:08 PM
Tacrolimus for kidney transplant patients only $30.36 for 5mg 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky
Reposted by Shreyank Tripathi
Cellcept for kidney transplant patients only $9.66 for 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky
January 12, 2025 at 8:00 PM
Cellcept for kidney transplant patients only $9.66 for 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky
Reposted by Shreyank Tripathi
December 15, 2024 at 8:26 PM
Reposted by Shreyank Tripathi
Goals and dreams are great... as long as they don't come at the cost of our mental and physical health.
Being comfortable is ok. Being good enough is ok.
"It's fine if you don't do that."
www.irishtimes.com/life-style/p...
Being comfortable is ok. Being good enough is ok.
"It's fine if you don't do that."
www.irishtimes.com/life-style/p...
Patrick Freyne: I am becoming a demotivational speaker – let’s all have an averagely productive December
I keep meeting people who are extremely burned out. I meet them so often that I’m beginning to think burnout is something that exists by design
www.irishtimes.com
December 15, 2024 at 1:30 PM
Goals and dreams are great... as long as they don't come at the cost of our mental and physical health.
Being comfortable is ok. Being good enough is ok.
"It's fine if you don't do that."
www.irishtimes.com/life-style/p...
Being comfortable is ok. Being good enough is ok.
"It's fine if you don't do that."
www.irishtimes.com/life-style/p...
#askrenal Pt with multiple cysts on the kidney ( appears to be ADPKD) but has ADTKD-UMOD ( confirmed genetic testing), non nephrotic proteinuria , progressive CKD: how would you treat this pt : RAASi and what else
December 4, 2024 at 11:33 PM
#askrenal Pt with multiple cysts on the kidney ( appears to be ADPKD) but has ADTKD-UMOD ( confirmed genetic testing), non nephrotic proteinuria , progressive CKD: how would you treat this pt : RAASi and what else
Shrey Tripathi , Richmond, VA. #nephJC
Lots of conflicts in renal world about this issue and lots of interest in tonight’s JC. But no COI.
Lots of conflicts in renal world about this issue and lots of interest in tonight’s JC. But no COI.
December 4, 2024 at 2:05 AM
Shrey Tripathi , Richmond, VA. #nephJC
Lots of conflicts in renal world about this issue and lots of interest in tonight’s JC. But no COI.
Lots of conflicts in renal world about this issue and lots of interest in tonight’s JC. But no COI.
Reposted by Shreyank Tripathi
Welcome everyone to #NephJC!
Tonight, we will take a ROAD less, or maybe more often traveled lately. BPROAD tests the lower limits of BP, potential benefits, and harms in patients with diabetes
www.nejm.org/doi/ful...
Tonight, we will take a ROAD less, or maybe more often traveled lately. BPROAD tests the lower limits of BP, potential benefits, and harms in patients with diabetes
www.nejm.org/doi/ful...
December 4, 2024 at 2:00 AM
Welcome everyone to #NephJC!
Tonight, we will take a ROAD less, or maybe more often traveled lately. BPROAD tests the lower limits of BP, potential benefits, and harms in patients with diabetes
www.nejm.org/doi/ful...
Tonight, we will take a ROAD less, or maybe more often traveled lately. BPROAD tests the lower limits of BP, potential benefits, and harms in patients with diabetes
www.nejm.org/doi/ful...
Reposted by Shreyank Tripathi
1/9
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
November 28, 2024 at 2:40 AM
1/9
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.
And yet, it isn't.
Let's examine why.
Reposted by Shreyank Tripathi
The #CSNAGM will be in Vancouver in May 2025
Only a couple of days left to submit your abstract: catalyst.omnipress.com#event-home/c...!
Only a couple of days left to submit your abstract: catalyst.omnipress.com#event-home/c...!
November 27, 2024 at 2:57 PM
The #CSNAGM will be in Vancouver in May 2025
Only a couple of days left to submit your abstract: catalyst.omnipress.com#event-home/c...!
Only a couple of days left to submit your abstract: catalyst.omnipress.com#event-home/c...!
“The first method for estimating the intelligence of a ruler is to look at the men he has around him.”
― Niccolò Machiavelli
― Niccolò Machiavelli
November 23, 2024 at 6:58 PM
“The first method for estimating the intelligence of a ruler is to look at the men he has around him.”
― Niccolò Machiavelli
― Niccolò Machiavelli
Anyway to bookmark a post?
November 23, 2024 at 4:14 PM
Anyway to bookmark a post?
Reposted by Shreyank Tripathi
Created a #nephbbq starter pack from those who tagged previously that I cd find -
go.bsky.app/Bx5sCJ8
go.bsky.app/Bx5sCJ8
November 23, 2024 at 3:07 PM
Created a #nephbbq starter pack from those who tagged previously that I cd find -
go.bsky.app/Bx5sCJ8
go.bsky.app/Bx5sCJ8
SGLT-2 inhibitor for patients with nephrolithiasis.
November 23, 2024 at 2:34 PM
SGLT-2 inhibitor for patients with nephrolithiasis.
High consumption of UPF is associated with increased hypertension risk. #AcademicSky #MedSky #NephSky
November 23, 2024 at 2:31 PM
High consumption of UPF is associated with increased hypertension risk. #AcademicSky #MedSky #NephSky