The retina can easily detect whether the eye is too small or too big thanks to the imperfections of the eye optics.

Vertebrate eyes first evolved in water, where spectral content rapidly fades with distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the background, pointing to distance es...

Animals encounter predators and prey under diverse lighting conditions that signal different risks and opportunities, yet how ambient illumination shapes innate approach and avoidance behaviors remain...

Nature Communications - LRFN2 in cone photoreceptors is vital for building the OFF pathway. Here authors report this cell-adhesion molecule stabilizes contacts with OFF bipolar cells, clusters...

A connectome of the right optic lobe from a male fruitfly is presented together with an extensive collection of genetic drivers matched to a comprehensive neuron-type catalogue.

Gonzalez-Aponte et al. identify daily glucocorticoid receptor signaling as an intrinsic driver of glioblastoma (GBM) progression and a synchronizer of tumor clock gene expression to the host. This work provides an intrinsic circadian driver, and therapeutic target, to slow GBM growth, and offers considerations for glucocorticoid use in the clinic.

Light exerts circadian-independent effects on glucose and lipid metabolism.

Species-specific gaze shifts with natural stimuli drive correlated spiking in retinal ganglion cells.

Housset et al. show that basal bodies of cone photoreceptors in the mouse retina are planar polarized in a light-dependent manner by the action of transducin and G-protein-signaling modulator protein ...