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karthala-system.bsky.social
Karthala system
@karthala-system.bsky.social
Acousto-optic two-photon microscopy system

karthalasystem.com
Pinned
The AODscopeHUB! It makes the two-photon imaging system as versatile as you need: double the imaging setup, while using the same scanner and detection system! An ideal solution for an imaging facility and multi-user environment
Reposted by Karthala system
🧵 New paper out🚨🧠! Information about motion is key to vision. Head motion signals from the vestibular system robustly modulate visual cortex activity. Despite this profound modulation, we still don’t know how these signals reach visual cortex - or even what aspects of head motion are transmitted.
🤯 👁️ Did you know the primary visual cortex tracks head movements even in complete darkness?

Guy Bouvier and colleagues managed to decode multiple head movement variables in V1 without light in the room, and discovered two distinct brain sources delivering these signals!

Read more in PNAS 🔽🔽
www.pnas.org
October 18, 2025 at 7:00 AM
Reposted by Karthala system
#OCaMP is now on bioRxiv and reagents are available on #Addgene! 🧪

A sensitive orange fluorescent calcium ion indicator for imaging neural activity

www.biorxiv.org/content/10.1...
A sensitive orange fluorescent calcium ion indicator for imaging neural activity
Genetically encoded calcium indicators (GECIs) are vital tools for fluorescence-based visualization of neuronal activity with high spatial and temporal resolution. However, current highest-performance...
www.biorxiv.org
July 31, 2025 at 7:34 PM
Reposted by Karthala system
Mind the deadlines for our 11th international conference "BrainBody - Exploring bidirectional crosstalk between the central nervous system and the body"!
⏳ Early bird registration and abstract submission deadline: July 1st!
📅 1-3 October 2025
📍 Bordeaux, France

👉 brainconf.u-bordeaux.fr/en/
June 16, 2025 at 9:59 AM
Reposted by Karthala system
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
May 12, 2025 at 5:25 AM
Reposted by Karthala system
(Plz repost)

I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, neural circuit dynamics, and/or hearing rehabilitation.

pierre.apostolides @ umich .edu

Tyvm
April 17, 2025 at 9:53 AM
Reposted by Karthala system
✨ Announcing a new glutamate indicator - iGluSnFR4! ✨

Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.

More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...

🧠📈
March 25, 2025 at 10:24 PM
Reposted by Karthala system
That was a fun project! Thanks to Rob Lees, Adam Packer, and all the co-authors for inviting me to participate.
rdcu.be/edQXi
Standardized measurements for monitoring and comparing multiphoton microscope systems
Nature Protocols - A set of procedures is described here for standardizing the evaluation of multiphoton microscope performance, covering laser power, pulse width optimizations, field of view,...
rdcu.be
March 17, 2025 at 12:08 PM
Reposted by Karthala system
Are you using GCaMP8 or are planning to switch from GCaMP6? Then check out this new preprint from our lab! www.biorxiv.org/content/10.1...

- Calcium imaging
- GCaMP8 vs. GCaMP6
- Spike inference
- Imaging + ephys ground truth

With F. Helmchen, K. Svoboda, M. Rozsa & X. Fang.
March 11, 2025 at 11:30 AM
Reposted by Karthala system
#SaveTheDate📢 Rdv for the 7th International Frontiers in Neurophotonics 2025 #FINS2025!

On the programme: experts in #microscopy and #neuroscience🔬🧠

🗓️From 6 to 9 October
📍Bordeaux (France)🍷
📝 Registration opens soon

frontiersneurophotonics.org
February 3, 2025 at 9:23 AM
Reposted by Karthala system
Save the date !
Frontiers in Neurophotonics Symposium 2025 in Bordeaux
October 6-9
frontiersneurophotonics.org/2025-speakers/
🧪
2025 Speakers – International Frontiers in Neurophotonics Symposium
frontiersneurophotonics.org
February 5, 2025 at 2:08 PM
Reposted by Karthala system
#MiFoBio2025

The autumn microscopy school by @gdrimabio.bsky.social will take place from 10th to 16th October 2025.

The call for workshops to share pratical knowledges is open till 31/01 ateliers-mifobio.fr

We'll bring stuff as usual, stay tuned !

More information 👉 linktr.ee/gdrimabio
January 20, 2025 at 11:26 AM
Reposted by Karthala system
Seems like there is a new ultracompact #femtosecond #laser source for #multiphoton #microscopy in town! 50 MHz rep rate means a 2-3 m cavity if there is a single pulse circulating in the cavity - folding that into that compact of a form factor is quite impressive!
www.laseratwork.com/products-ove...
January 27, 2025 at 7:50 AM
Reposted by Karthala system
An Open-Source Joystick Platform for Investigating Forelimb Motor Control, Auditory-Motor Integration, and Value-Based Decision-Making in Head-Fixed Mice https://www.biorxiv.org/content/10.1101/2025.01.23.634598v1
January 24, 2025 at 3:15 AM
The AODscopeHUB! It makes the two-photon imaging system as versatile as you need: double the imaging setup, while using the same scanner and detection system! An ideal solution for an imaging facility and multi-user environment
January 23, 2025 at 4:28 PM
Reposted by Karthala system
Catching up from the dead time w/o X, here is the excellent recently published study by Sara Jamali with @standehaene.bsky.social using the local-global prediction paradigm in mice. Oddball signaling is not just adaptation. Sequence chunking responses in VIPs. And some more doi.org/10.7554/eLif...
Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex
Responses to local and global violations in sound sequences are prediction errors and not simply the consequence of stimulus-specific adaptation.
doi.org
January 19, 2025 at 5:15 PM
Reposted by Karthala system
Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro
Apply by: February 16th!
January 14, 2025 at 4:58 AM
Reposted by Karthala system
Applications to the 2025 Paris Spring School in Optical Imaging and Electrophysiological Recording in Neuroscience (AKA the Paris Neuro Course) are now open. Deadline on the 1st of February.

The course will run 14-27 May 2025.

parisneuro.ovh
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience
parisneuro.ovh
December 22, 2024 at 2:34 PM