Julien Cherfils Vicini
@juliencherfils.bsky.social
Team Leader @ircaninstitute Passionated by immunosurveillance to fight aging and cancer
Reposted by Julien Cherfils Vicini
#RésultatScientifique🔎 | Vieillissement : un bouclier levé ?
@juliencherfils.bsky.social et ses collaborateurs ont découvert comment un glycolipide protège les cellules sénescentes du système immunitaire. En le ciblant, ils parviennent à réduire les effets du vieillissement chez la souris ! 🧪
@juliencherfils.bsky.social et ses collaborateurs ont découvert comment un glycolipide protège les cellules sénescentes du système immunitaire. En le ciblant, ils parviennent à réduire les effets du vieillissement chez la souris ! 🧪
Une nouvelle cible pour lutter contre les maladies chroniques liées au vieillissement
Le vieillissement entraîne une accumulation de cellules sénescentes qui échappent au système immunitaire et contribuent à des maladies chroniques telles que l
buff.ly
March 11, 2025 at 5:01 PM
#RésultatScientifique🔎 | Vieillissement : un bouclier levé ?
@juliencherfils.bsky.social et ses collaborateurs ont découvert comment un glycolipide protège les cellules sénescentes du système immunitaire. En le ciblant, ils parviennent à réduire les effets du vieillissement chez la souris ! 🧪
@juliencherfils.bsky.social et ses collaborateurs ont découvert comment un glycolipide protège les cellules sénescentes du système immunitaire. En le ciblant, ils parviennent à réduire les effets du vieillissement chez la souris ! 🧪
Deeply honored by this News & Views! doi.org/10.1038/s435...
Huge thanks to @Krizhanovsky, @Mejewska and @NatureAging.bsky.social for highlighting our paper rdcu.be/d6wko
@ircaninstitute @Univ_CotedAzur @CNRsbiologie.bsky.social
@Inserm.fr @iltischarlene.bsky.social
@irynamoskalevska.bsky.social
Huge thanks to @Krizhanovsky, @Mejewska and @NatureAging.bsky.social for highlighting our paper rdcu.be/d6wko
@ircaninstitute @Univ_CotedAzur @CNRsbiologie.bsky.social
@Inserm.fr @iltischarlene.bsky.social
@irynamoskalevska.bsky.social
GD3 ganglioside checkpoints in immune surveillance of senescent cells - Nature Aging
Iltis, Moskalevska and colleagues investigate how the innate immune system regulates the age-related accumulation of senescent cells. They show that upregulation of the GD3 ganglioside-based immune ch...
doi.org
January 16, 2025 at 10:45 PM
Deeply honored by this News & Views! doi.org/10.1038/s435...
Huge thanks to @Krizhanovsky, @Mejewska and @NatureAging.bsky.social for highlighting our paper rdcu.be/d6wko
@ircaninstitute @Univ_CotedAzur @CNRsbiologie.bsky.social
@Inserm.fr @iltischarlene.bsky.social
@irynamoskalevska.bsky.social
Huge thanks to @Krizhanovsky, @Mejewska and @NatureAging.bsky.social for highlighting our paper rdcu.be/d6wko
@ircaninstitute @Univ_CotedAzur @CNRsbiologie.bsky.social
@Inserm.fr @iltischarlene.bsky.social
@irynamoskalevska.bsky.social
Reposted by Julien Cherfils Vicini
Study shows that senescent cells literally sugar-coat themselves to avoid recognition and clearance by the immune system.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging - Nature Aging
This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to aging and age-rel...
www.nature.com
December 28, 2024 at 7:33 PM
Study shows that senescent cells literally sugar-coat themselves to avoid recognition and clearance by the immune system.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Reposted by Julien Cherfils Vicini
This paper, coupled with the Perspective from Neuron, really indicates that our understanding of the immune system on an aging brain could well be entering a new phase - one with lots of great data rather than mainly conjecture.
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
December 27, 2024 at 7:45 PM
This paper, coupled with the Perspective from Neuron, really indicates that our understanding of the immune system on an aging brain could well be entering a new phase - one with lots of great data rather than mainly conjecture.
www.cell.com/neuron/abstr...
www.cell.com/neuron/abstr...
1/7 Excited to share our team’s first paper revealing how senescent cells use the GD3 ganglioside as a Senescence Immune Checkpoints (SICs) to bypass immune surveillance published in @NatureAging! rdcu.be/d4XXJ
A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during aging
Nature Aging - This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to...
rdcu.be
December 27, 2024 at 12:19 PM
1/7 Excited to share our team’s first paper revealing how senescent cells use the GD3 ganglioside as a Senescence Immune Checkpoints (SICs) to bypass immune surveillance published in @NatureAging! rdcu.be/d4XXJ
What an incredible year! 🎉🚀 Huge thanks to my amazing team and collaborators! New talent, new lab under construction (moving in Jan 2025!), fantastic meetings (Chile, Shanghai) & paper accepted in @NatureAging (stay tuned!). Wishing everyone a Merry Christmas and an even more amazing 2025! 🎄✨
December 20, 2024 at 9:36 AM
What an incredible year! 🎉🚀 Huge thanks to my amazing team and collaborators! New talent, new lab under construction (moving in Jan 2025!), fantastic meetings (Chile, Shanghai) & paper accepted in @NatureAging (stay tuned!). Wishing everyone a Merry Christmas and an even more amazing 2025! 🎄✨