Julia Eberhard
jueberhard.bsky.social
Julia Eberhard
@jueberhard.bsky.social
Hunter Lab PhD candidate studying immune responses to chronic 🧠 infection. Lover of rock music and rock climbing.
Stanford '18 | IGGPenn '2_?
Pinned
Happy to share that our paper on immune targeting of T. gondii cysts and the role of this stage in persistence is finally out in @naturemicrobiol.bsky.social - Thanks again to all co-authors who made this possible!

www.nature.com/articles/s41...
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii - Nature Microbiology
In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
www.nature.com
Reposted by Julia Eberhard
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits

www.nature.com/articles/s41...
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits - Nature Neuroscience
Chronic brain infection and IL-1 exposure impair spatial memory by triggering DNA double-strand break signaling in hippocampal neurons. Blocking this pathway prevents memory deficits, suggesting new t...
www.nature.com
September 4, 2025 at 2:04 PM
Reposted by Julia Eberhard
Ha - big week for IL-12... De-coupling immune parameters and toxicity associated with IL-12 agonism: Cell Reports www.cell.com/cell-reports...
De-coupling immune parameters and toxicity associated with IL-12 agonism
Lanzar et al. use a combination of half-life extension and IL-12 variants to explore the toxic effects of IL-12 treatment. These datasets highlight the cellular pool of innate and adaptive lymphocytes...
www.cell.com
June 14, 2025 at 9:09 PM
Reposted by Julia Eberhard
Reposted by Julia Eberhard
For those still interested in infection and the brain - here is a nice mix of math and pathogens - that tests the function of latency and how the immune system deals with a neuronal infection. Lots going on here to dissect - but turns out latency benefits host and parasite.
rdcu.be/efknc
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
Nature Microbiology - In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
rdcu.be
March 27, 2025 at 11:14 AM
Happy to share that our paper on immune targeting of T. gondii cysts and the role of this stage in persistence is finally out in @naturemicrobiol.bsky.social - Thanks again to all co-authors who made this possible!

www.nature.com/articles/s41...
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii - Nature Microbiology
In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
www.nature.com
March 27, 2025 at 1:59 PM
Reposted by Julia Eberhard
The latent stage of Toxoplasma gondii is targeted by the immune response and host protective https://www.biorxiv.org/content/10.1101/2024.03.05.583527v1
The latent stage of Toxoplasma gondii is targeted by the immune response and host protective https://www.biorxiv.org/content/10.1101/2024.03.05.583527v1
Latency is a microbial strategy for persistence. For Toxoplasma gondii the ability of the bradyzoite
www.biorxiv.org
March 6, 2024 at 3:22 AM
Reposted by Julia Eberhard
Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain. https://www.biorxiv.org/content/10.1101/2024.01.21.576564v1
Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain. https://www.biorxiv.org/content/10.1101/2024.01.21.576564v1
Toxoplasma gondii (T. gondii), a common brain-tropic parasite, chronically infects the central nervo
www.biorxiv.org
January 24, 2024 at 3:19 AM
Experimenting with some cursed brain candy canes 🧠🍭
January 23, 2024 at 10:33 PM