Julia Eberhard
@jueberhard.bsky.social
Hunter Lab PhD candidate studying immune responses to chronic 🧠 infection. Lover of rock music and rock climbing.
Stanford '18 | IGGPenn '2_?
Stanford '18 | IGGPenn '2_?
Pinned
Julia Eberhard
@jueberhard.bsky.social
· Mar 27
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii - Nature Microbiology
In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
www.nature.com
Happy to share that our paper on immune targeting of T. gondii cysts and the role of this stage in persistence is finally out in @naturemicrobiol.bsky.social - Thanks again to all co-authors who made this possible!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julia Eberhard
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits - Nature Neuroscience
Chronic brain infection and IL-1 exposure impair spatial memory by triggering DNA double-strand break signaling in hippocampal neurons. Blocking this pathway prevents memory deficits, suggesting new t...
www.nature.com
September 4, 2025 at 2:04 PM
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julia Eberhard
Ha - big week for IL-12... De-coupling immune parameters and toxicity associated with IL-12 agonism: Cell Reports www.cell.com/cell-reports...
De-coupling immune parameters and toxicity associated with IL-12 agonism
Lanzar et al. use a combination of half-life extension and IL-12 variants to explore
the toxic effects of IL-12 treatment. These datasets highlight the cellular pool of
innate and adaptive lymphocytes...
www.cell.com
June 14, 2025 at 9:09 PM
Ha - big week for IL-12... De-coupling immune parameters and toxicity associated with IL-12 agonism: Cell Reports www.cell.com/cell-reports...
Reposted by Julia Eberhard
OUT NOW: Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
@jueberhard.bsky.social @kingofpathogens.bsky.social
#microsky 🧪
www.nature.com/articles/s41...
@jueberhard.bsky.social @kingofpathogens.bsky.social
#microsky 🧪
www.nature.com/articles/s41...
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii - Nature Microbiology
In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
www.nature.com
March 27, 2025 at 4:32 PM
OUT NOW: Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
@jueberhard.bsky.social @kingofpathogens.bsky.social
#microsky 🧪
www.nature.com/articles/s41...
@jueberhard.bsky.social @kingofpathogens.bsky.social
#microsky 🧪
www.nature.com/articles/s41...
Reposted by Julia Eberhard
For those still interested in infection and the brain - here is a nice mix of math and pathogens - that tests the function of latency and how the immune system deals with a neuronal infection. Lots going on here to dissect - but turns out latency benefits host and parasite.
rdcu.be/efknc
rdcu.be/efknc
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
Nature Microbiology - In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
rdcu.be
March 27, 2025 at 11:14 AM
For those still interested in infection and the brain - here is a nice mix of math and pathogens - that tests the function of latency and how the immune system deals with a neuronal infection. Lots going on here to dissect - but turns out latency benefits host and parasite.
rdcu.be/efknc
rdcu.be/efknc
Happy to share that our paper on immune targeting of T. gondii cysts and the role of this stage in persistence is finally out in @naturemicrobiol.bsky.social - Thanks again to all co-authors who made this possible!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii - Nature Microbiology
In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
www.nature.com
March 27, 2025 at 1:59 PM
Happy to share that our paper on immune targeting of T. gondii cysts and the role of this stage in persistence is finally out in @naturemicrobiol.bsky.social - Thanks again to all co-authors who made this possible!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Julia Eberhard
The latent stage of Toxoplasma gondii is targeted by the immune response and host protective https://www.biorxiv.org/content/10.1101/2024.03.05.583527v1
The latent stage of Toxoplasma gondii is targeted by the immune response and host protective https://www.biorxiv.org/content/10.1101/2024.03.05.583527v1
Latency is a microbial strategy for persistence. For Toxoplasma gondii the ability of the bradyzoite
www.biorxiv.org
March 6, 2024 at 3:22 AM
The latent stage of Toxoplasma gondii is targeted by the immune response and host protective https://www.biorxiv.org/content/10.1101/2024.03.05.583527v1
Reposted by Julia Eberhard
Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain. https://www.biorxiv.org/content/10.1101/2024.01.21.576564v1
Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain. https://www.biorxiv.org/content/10.1101/2024.01.21.576564v1
Toxoplasma gondii (T. gondii), a common brain-tropic parasite, chronically infects the central nervo
www.biorxiv.org
January 24, 2024 at 3:19 AM
Chronic Toxoplasma gondii infection curtails the cytotoxic potential of acute T cell responses to West Nile virus in the brain. https://www.biorxiv.org/content/10.1101/2024.01.21.576564v1
Experimenting with some cursed brain candy canes 🧠🍭
January 23, 2024 at 10:33 PM
Experimenting with some cursed brain candy canes 🧠🍭