@KingOfPathogens
@kingofpathogens.bsky.social
🏴 Cytokines Parasites
Pinned
Immunology
open.spotify.com
Because @jengommerman.bsky.social got so humpty about my response to her musical suggestions 🙄- here is the first public offering of the playlist for immunologists. Need more B cell help. @victora.bsky.social @marionpepper.bsky.social
open.spotify.com/playlist/0aC...
open.spotify.com/playlist/0aC...
Reposted by @KingOfPathogens
Targeting TLR7 or downstream effectors may represent a promising strategy to alleviate chronic pain induced by lupus
www.mdpi.com/2073-4409/15...
www.mdpi.com/2073-4409/15...
December 23, 2025 at 3:29 AM
Targeting TLR7 or downstream effectors may represent a promising strategy to alleviate chronic pain induced by lupus
www.mdpi.com/2073-4409/15...
www.mdpi.com/2073-4409/15...
Reposted by @KingOfPathogens
IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis @pnas.org @kingofpathogens.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
December 18, 2025 at 3:58 AM
IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis @pnas.org @kingofpathogens.bsky.social
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by @KingOfPathogens
T follicular helper cells adopt alter egos and localize to diverse niches - what gene expression programs distinguish Tfh in the germinal center? After dissociating tissue samples into single-cell suspension, can we infer which Tfh were positioned in GCs? Check out our new preprint! bit.ly/3XVsrCI
Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans
CD4 T follicular helper (Tfh) cells coordinate humoral immune responses within germinal centers (GC) of lymphoid tissue. Despite their critical roles in vaccination and autoimmunity, the gene expressi...
bit.ly
December 15, 2025 at 5:03 PM
T follicular helper cells adopt alter egos and localize to diverse niches - what gene expression programs distinguish Tfh in the germinal center? After dissociating tissue samples into single-cell suspension, can we infer which Tfh were positioned in GCs? Check out our new preprint! bit.ly/3XVsrCI
Reposted by @KingOfPathogens
Cytokines 2026 in Glasgow (Oct 18-21) has an incredible Scientific Organizing Committee! Simon Jones, Iain McInnes, Clare Bryant, Clare Lloyd, and Luke O'Neill creating the program. This one's going to be special.
Details: 2026.cytokinesociety.org
Details: 2026.cytokinesociety.org
December 11, 2025 at 6:56 AM
Cytokines 2026 in Glasgow (Oct 18-21) has an incredible Scientific Organizing Committee! Simon Jones, Iain McInnes, Clare Bryant, Clare Lloyd, and Luke O'Neill creating the program. This one's going to be special.
Details: 2026.cytokinesociety.org
Details: 2026.cytokinesociety.org
Reposted by @KingOfPathogens
Urs Mörbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyer’s patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/...
#IBD
#IBD
December 11, 2025 at 5:04 PM
Urs Mörbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyer’s patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/...
#IBD
#IBD
In the year that Tregs get the respect they deserve - here is our contribution to help understand what regulates their homeostasis. One for lovers of cytokines and Tregs! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
December 10, 2025 at 12:16 PM
In the year that Tregs get the respect they deserve - here is our contribution to help understand what regulates their homeostasis. One for lovers of cytokines and Tregs! www.pnas.org/doi/10.1073/...
Reposted by @KingOfPathogens
The top 10 people of 2025 @nature.com who shaped science.
Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity"
www.nature.com/immersive/d4...
Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity"
www.nature.com/immersive/d4...
December 8, 2025 at 5:05 PM
The top 10 people of 2025 @nature.com who shaped science.
Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity"
www.nature.com/immersive/d4...
Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity"
www.nature.com/immersive/d4...
Reposted by @KingOfPathogens
The United States "is losing its long-held lead as a research powerhouse and collaborator in world science." www.nature.com/articles/d41...
China’s scientific clout is growing as US influence wanes: the data show how
An analysis of international research collaborations reveals the growing dominance of Chinese science.
www.nature.com
December 8, 2025 at 5:21 PM
The United States "is losing its long-held lead as a research powerhouse and collaborator in world science." www.nature.com/articles/d41...
Reposted by @KingOfPathogens
A new review explores one of the themes of my book Air-Borne: our lungs are like the ocean. Both send life into the atmosphere. pubs.acs.org/doi/full/10....
December 7, 2025 at 9:26 PM
A new review explores one of the themes of my book Air-Borne: our lungs are like the ocean. Both send life into the atmosphere. pubs.acs.org/doi/full/10....
Reposted by @KingOfPathogens
Vaccinating newborns against hepatitis B saves lives. Why might a CDC panel stop recommending it? www.cidrap.umn.edu/childhood-va...
Vaccinating newborns against hepatitis B saves lives. Why might a CDC panel stop recommending it?
www.cidrap.umn.edu
December 3, 2025 at 3:24 PM
Vaccinating newborns against hepatitis B saves lives. Why might a CDC panel stop recommending it? www.cidrap.umn.edu/childhood-va...
Reposted by @KingOfPathogens
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection
Nature Microbiology - The Toxoplasma gondii effector TgROP1 mimics host factors to bind VAPA/B, thereby establishing parasite–host ER contact sites.
rdcu.be
November 25, 2025 at 5:24 PM
🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!!
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Host organelle - pathogen membrane contact sites!! ER edition!
rdcu.be/eRKUM
Reposted by @KingOfPathogens
In AIR-BORNE, I wrote about the reluctance many scientists had to acknowledge Covid can float to new hosts. Now it looks like something similar may be happening with bird flu, which may be blowing from farm to farm. Story in @propublica.org www.propublica.org/article/bird...
What the U.S. Government Is Dismissing That Could Seed a Bird Flu Pandemic
Egg producers suspect bird flu is traveling through the air. After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed. Vacci...
www.propublica.org
November 19, 2025 at 1:00 AM
In AIR-BORNE, I wrote about the reluctance many scientists had to acknowledge Covid can float to new hosts. Now it looks like something similar may be happening with bird flu, which may be blowing from farm to farm. Story in @propublica.org www.propublica.org/article/bird...
Reposted by @KingOfPathogens
Stimulating day at MRC Biomedicine Science Conference. Super keynote from Sarah Teichmann, Entertaining and thought provoking talk from George Davey Smith, MRC Millennium Medal recipient, and amazing views from the loo
@mendelrandom.bsky.social @ukri.org
@mendelrandom.bsky.social @ukri.org
November 19, 2025 at 12:05 AM
Stimulating day at MRC Biomedicine Science Conference. Super keynote from Sarah Teichmann, Entertaining and thought provoking talk from George Davey Smith, MRC Millennium Medal recipient, and amazing views from the loo
@mendelrandom.bsky.social @ukri.org
@mendelrandom.bsky.social @ukri.org
Reposted by @KingOfPathogens
There's a word for learning from evolution's inventions: bioinspiration. Here's my interactive story on the way animals and plants fuel technological creativity. Gift link: nyti.ms/4otNQyl
How Inventors Find Inspiration in Evolution (Gift Article)
Soft batteries and water-walking robots are among the many creations made possible by studying animals and plants.
nyti.ms
November 10, 2025 at 3:37 PM
There's a word for learning from evolution's inventions: bioinspiration. Here's my interactive story on the way animals and plants fuel technological creativity. Gift link: nyti.ms/4otNQyl
Reposted by @KingOfPathogens
Nov issue of #Science #Immunology out now!
This week: exTH17 cells sustain #IL17 –independent rheumatoid #arthritis; CXCR4+ mesodermal progenitors → rostral blood vessels, prodefinitive hematopoiesis, & postnatal tissue #macrophages; & how #Bcells acquire antigens from #parasites!
scim.ag/4qQA6Q6
This week: exTH17 cells sustain #IL17 –independent rheumatoid #arthritis; CXCR4+ mesodermal progenitors → rostral blood vessels, prodefinitive hematopoiesis, & postnatal tissue #macrophages; & how #Bcells acquire antigens from #parasites!
scim.ag/4qQA6Q6
November 7, 2025 at 10:19 PM
Nov issue of #Science #Immunology out now!
This week: exTH17 cells sustain #IL17 –independent rheumatoid #arthritis; CXCR4+ mesodermal progenitors → rostral blood vessels, prodefinitive hematopoiesis, & postnatal tissue #macrophages; & how #Bcells acquire antigens from #parasites!
scim.ag/4qQA6Q6
This week: exTH17 cells sustain #IL17 –independent rheumatoid #arthritis; CXCR4+ mesodermal progenitors → rostral blood vessels, prodefinitive hematopoiesis, & postnatal tissue #macrophages; & how #Bcells acquire antigens from #parasites!
scim.ag/4qQA6Q6
Reposted by @KingOfPathogens
After many rewarding years at @StJudeResearch surrounded by exceptional colleagues & groundbreaking science, I’m delighted to join @fredhutch to push boundaries in viral & cancer immunology. Grateful to St. Jude and looking forward to what’s next at FH! More here: www.fredhutch.org/en/news/cent...
Viral immunologist taps ‘incredible potential’ of immune system
New Fred Hutch Cancer Center viral immunologist Dr. Paul Thomas is working to turn the "incredible potential" of the immune system into real-life diagnostic and therapeutic applications. He studies ho...
www.fredhutch.org
November 7, 2025 at 9:12 PM
After many rewarding years at @StJudeResearch surrounded by exceptional colleagues & groundbreaking science, I’m delighted to join @fredhutch to push boundaries in viral & cancer immunology. Grateful to St. Jude and looking forward to what’s next at FH! More here: www.fredhutch.org/en/news/cent...
Reposted by @KingOfPathogens
On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...
What Rosalind Franklin truly contributed to the discovery of DNA’s structure
Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.
www.nature.com
November 7, 2025 at 9:25 PM
On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...
Reposted by @KingOfPathogens
Your cat when you're choking to death in your apartment
November 6, 2025 at 9:16 PM
Your cat when you're choking to death in your apartment
Reposted by @KingOfPathogens
I need a gyro!
I'm holding out for a gyro till the end of the night!
It's gotta be warm
and its gotta be fast
and its gotta be fresh made tonight
I'm holding out for a gyro till the end of the night!
It's gotta be warm
and its gotta be fast
and its gotta be fresh made tonight
November 5, 2025 at 10:45 PM
I need a gyro!
I'm holding out for a gyro till the end of the night!
It's gotta be warm
and its gotta be fast
and its gotta be fresh made tonight
I'm holding out for a gyro till the end of the night!
It's gotta be warm
and its gotta be fast
and its gotta be fresh made tonight
Lovers of Trained Immunity - this one is for you. A focused E-life issue on the topic - lots of ground to cover.
elifesciences.org/collections/...
elifesciences.org/collections/...
Focus Issue: Trained Immunity
Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.
elifesciences.org
November 6, 2025 at 11:51 AM
Lovers of Trained Immunity - this one is for you. A focused E-life issue on the topic - lots of ground to cover.
elifesciences.org/collections/...
elifesciences.org/collections/...
Neuroinflammatory canine disorders: unveiling disease mechanisms from a One Health perspective url: academic.oup.com/jimmunol/art...
Neuroinflammatory canine disorders: unveiling disease mechanisms from a One Health perspective
Abstract. While rodent models remain foundational in biomedical research for their manipulability, genetics, and reproducibility, spontaneous diseases in c
academic.oup.com
November 6, 2025 at 11:50 AM
Neuroinflammatory canine disorders: unveiling disease mechanisms from a One Health perspective url: academic.oup.com/jimmunol/art...
Reposted by @KingOfPathogens
What a great #Cytokines2025 meeting! Caught up with many #IFN scientists, made multiple new connections, had fun giving a talk & great to see those from UW Immunology all these years later. Always my fav conference 😀🥳 Thanks to all the organizers!🙏🏻 @cytokinesociety.bsky.social @ramlabuw.bsky.social
November 5, 2025 at 11:18 PM
What a great #Cytokines2025 meeting! Caught up with many #IFN scientists, made multiple new connections, had fun giving a talk & great to see those from UW Immunology all these years later. Always my fav conference 😀🥳 Thanks to all the organizers!🙏🏻 @cytokinesociety.bsky.social @ramlabuw.bsky.social
Has no one seen The Mummy? This seems like a terrible, terrible idea! What could go wrong? www.theguardian.com/world/2025/o...
Egypt’s vast $1bn museum to open in Cairo after two-decade build
Grand Egyptian Museum near Giza pyramids billed as world’s largest archaeological facility for single civilisation
www.theguardian.com
November 5, 2025 at 12:00 AM
Has no one seen The Mummy? This seems like a terrible, terrible idea! What could go wrong? www.theguardian.com/world/2025/o...
Reposted by @KingOfPathogens
#Cytokines2025 has begun- looking forward to a few days of networking, especially with #IFN friends from outside 🇨🇦 when it has been too long 😀
Despite the challenge of travel to the US at the moment, still 20 countries represented this year 🌎
#Cytokines25 @cytokinesociety.bsky.social
Despite the challenge of travel to the US at the moment, still 20 countries represented this year 🌎
#Cytokines25 @cytokinesociety.bsky.social
November 3, 2025 at 12:23 AM
#Cytokines2025 has begun- looking forward to a few days of networking, especially with #IFN friends from outside 🇨🇦 when it has been too long 😀
Despite the challenge of travel to the US at the moment, still 20 countries represented this year 🌎
#Cytokines25 @cytokinesociety.bsky.social
Despite the challenge of travel to the US at the moment, still 20 countries represented this year 🌎
#Cytokines25 @cytokinesociety.bsky.social
Reposted by @KingOfPathogens
Welcome to #Cytokines2025!
We are thrilled to have you in Seattle for cytokines2025. Check in starts at 11 am, join us for cutting-edge scientific sessions, celebrate excellence at the award ceremony, and connect at the welcome reception. Enjoy the meeting and Seattle! 🌲🧬✨ #Cytokines25 #Immunology
We are thrilled to have you in Seattle for cytokines2025. Check in starts at 11 am, join us for cutting-edge scientific sessions, celebrate excellence at the award ceremony, and connect at the welcome reception. Enjoy the meeting and Seattle! 🌲🧬✨ #Cytokines25 #Immunology
November 2, 2025 at 2:56 PM
Welcome to #Cytokines2025!
We are thrilled to have you in Seattle for cytokines2025. Check in starts at 11 am, join us for cutting-edge scientific sessions, celebrate excellence at the award ceremony, and connect at the welcome reception. Enjoy the meeting and Seattle! 🌲🧬✨ #Cytokines25 #Immunology
We are thrilled to have you in Seattle for cytokines2025. Check in starts at 11 am, join us for cutting-edge scientific sessions, celebrate excellence at the award ceremony, and connect at the welcome reception. Enjoy the meeting and Seattle! 🌲🧬✨ #Cytokines25 #Immunology