Joanna Qian Dong
banner
joannaqd.bsky.social
Joanna Qian Dong
@joannaqd.bsky.social
Postdoc in Götz lab, Helmholtz Munich and BMC, LMU, Munich, human neuronal reprogramming. Previous @ Cheng lab, fly neural development.
Reposted by Joanna Qian Dong
Nature research paper: Rewiring of cortical glucose metabolism fuels human brain cancer growth

go.nature.com/4lZtawb
Rewiring of cortical glucose metabolism fuels human brain cancer growth - Nature
The cortex fuels essential physiological processes with glucose-derived carbon, while gliomas fuel their aggressiveness by rerouting glucose carbon pathways and scavenging alternative carbon sources such as environmental amino acids, providing a potential therapeutic target.
go.nature.com
September 4, 2025 at 5:08 PM
Reposted by Joanna Qian Dong
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - @distefanolab.bsky.social @brumbaugh-lab.bsky.social go.nature.com/3X215du
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
go.nature.com
October 28, 2025 at 6:50 PM
Reposted by Joanna Qian Dong
Long thought of as support cells, astrocytes are emerging as key players in health and disease

go.nature.com/4pJn859
The ‘silent’ brain cells that shape our behaviour, memory and health
Astrocytes make up one-quarter of the brain, but researchers are only now realizing their true value.
go.nature.com
December 3, 2025 at 12:16 PM
Reposted by Joanna Qian Dong
🧬 Low-dose zinc, branched-chain amino acids and serine improved social behaviour in autism-linked mouse models and partly calmed overactive amygdala circuits. Early-stage work only. 🔗 Link to study in comments #Neuroscience #Autism #ScienceNews #BrainHealth #Research
December 2, 2025 at 9:33 PM
Reposted by Joanna Qian Dong
Now online! RNA innate immunity constitutes a barrier for interspecies chimerism
RNA innate immunity constitutes a barrier for interspecies chimerism
Interspecies PSC co-culture induces horizontal RNA transfer that activates innate immunity in “winner” mouse cells, a response that is alleviated by Mavs deletion, thereby enhancing “loser” human PSC survival and chimerism.
dlvr.it
November 24, 2025 at 3:59 PM
Reposted by Joanna Qian Dong
Tagging first author @joannaqd.bsky.social and collaborators @obataf-lab.bsky.social
🧠 New research shows the blood–brain barrier helps control #braintumour growth.

Led by Prof Louise Cheng, the study finds glial “gatekeeper” cells and a protein called Path influence how #cancer respond to low nutrients.

Read more: www.petermac.org/about-us/new...
November 24, 2025 at 3:19 AM
Reposted by Joanna Qian Dong
"A functional perspective on astrocyte heterogeneity"
http://dlvr.it/TPML8T

Benjamin Deneen, Wookbong Kwon & @m-r-williamson.bsky.social
@cp-trendsneuro.bsky.social
#SfN2025
November 19, 2025 at 10:21 PM
Reposted by Joanna Qian Dong
"Phase 1/2a clinical trial of hESC-derived dopamine progenitors in Parkinson’s disease"
http://dlvr.it/TPHGB7

Phil Hyu Lee, Dong-Wook Kim & colleagues
@cp-cell.bsky.social
#SfN2025
November 15, 2025 at 1:43 PM
Reposted by Joanna Qian Dong
How does the #tumor #microenvironment modulate sensitivity to nutrient restriction? @chengflylab.bsky.social &co show that this is regulated by the SCL36 amino acid transporter Pathetic at the #BloodBrainBarrier perineural glial cells in #Drosophila #brain tumors @plosbiology.org 🧪 plos.io/4ibwXWY
November 19, 2025 at 10:05 AM