Jon Magnus Johannesson
jmicrobe.bsky.social
Jon Magnus Johannesson
@jmicrobe.bsky.social
ID fellow at Duke University Hospital | MD | Fan of everything related to ID and microbiology | Amateur fan of biology in general
Reposted by Jon Magnus Johannesson
Make a huge mistake. Then make a false claim about how you fixed it.

They did it for PEPFAR.

Now Ebola.

I follow this particular topic VERY closely, so here's what really happened and why this isn't true AT ALL...🧵
Elon Musk: "We will make mistakes. We won't be perfect ... so for example, with USAID, one of the things we accidentally canceled very briefly was ebola prevention."
February 26, 2025 at 8:47 PM
Reposted by Jon Magnus Johannesson
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control
Despite being heavily infiltrated by immune cells, tuberculosis (TB) granulomas often subvert the host response to Mycobacterium tuberculosis (Mtb) infection and support bacterial persistence. We prev...
doi.org
February 24, 2025 at 10:16 PM
Reposted by Jon Magnus Johannesson
Improved Survival in Vascular Pythiosis with Surgery and Azithromycin, Doxycycline, and Itraconazole Therapy: A Phase II Multicenter, Open-Label, Single-Arm Trial

✅ Just Accepted
#IDSky
Improved Survival in Vascular Pythiosis with Surgery and Azithromycin, Doxycycline, and Itraconazole Therapy: A Phase II Multicenter, Open-Label, Single-Arm Trial
Vascular pythiosis, caused by Pythium insidiosum, is a life-threatening disease with high mortality rate in patients with residual disease post-surgery. This study evaluated the effectiveness of a combination therapy of surgery, azithromycin, doxycycline, and itraconazole.
buff.ly
February 22, 2025 at 12:29 AM
Reposted by Jon Magnus Johannesson
#medsky #IDsky #Episky 🧪
In light of the news today concerning the US's newly appointed HHS secretary, here is the CDC's current recommended vaccination schedule:
www.cdc.gov/vaccines/imz...
www.cdc.gov/vaccines/imz...
www.cdc.gov/vaccines/hcp...

I encourage you save these docs. Some thoughts 🧵:
www.cdc.gov
February 13, 2025 at 8:51 PM
Reposted by Jon Magnus Johannesson
Trying to function without data is like driving blindfolded.

A judge just ordered HHS, CDC, and FDA to restore deleted health info pages—because, shocker, doctors and researchers kinda need that info to do their jobs.

Access to data isn’t a luxury, it’s a necessity.
A federal judge ordered the nation’s premier health agencies to restore online access to several websites that monitor HIV, health risks for youths and assisted reproductive technologies, which were abruptly taken offline to ensure they complied with Trump’s recent executive order on gender.
Judge orders CDC, FDA to restore websites taken down after Trump gender order
U.S. District Judge John D. Bates granted a restraining order temporarily reversing the Trump administration’s moves to remove scientific data.
wapo.st
February 11, 2025 at 8:50 PM
Reposted by Jon Magnus Johannesson
I'm on service in the MICU this week, a place that is defined by a huge outlay of resources for what is often a small chance of saving one life. Just thinking about what's happened to USAID – arguably one of the best ROI you could ever hope to achieve in human health and flourishing? – is very hard.
February 5, 2025 at 11:06 PM
Reposted by Jon Magnus Johannesson
No. RFK Jr has dedicated the past two decades of his life to making it more likely that children will die of preventable illnesses.

The only "good stuff" he believes is that Americans should eat better and exercise more, something every institution of public health already promotes constantly.
Harris had an opportunity to appeal to the RFK voters who just want healthy food and she blew it.

By blowing RFK off entirely, it invited people to assume that Harris opposed RFK's entire agenda, even the good stuff.
December 13, 2024 at 9:17 PM
Reposted by Jon Magnus Johannesson
🆕✨Systematic review and meta-analysis
Toxin results cannot rule in or rule out CDI, and the decision whether to treat symptomatic NAAT+/EIA− patients for CDI should be based on clinical presentation and not on the toxin result #idsky #EMIMCC #medsky
journals.asm.org/doi/10.1128/...
Clinical significance of toxin EIA positivity in patients with suspected Clostridioides difficile infection: systematic review and meta-analysis | Journal of Clinical Microbiology
Clostridioides difficile infection (CDI) is a common cause of healthcare-associated infections and the leading cause of antibiotic-associated diarrhea. However, the laboratory diagnosis of CDI, primar...
journals.asm.org
December 13, 2024 at 4:25 PM
Reposted by Jon Magnus Johannesson
🔥🔥 NEW 🔥🔥
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
In this article a selection of notable peer-reviewed publications from 2024 are provided. Article Selection by: Bassam Ghanem, Pharm.D., MS, BCPS Article Construction by: Timothy P. Gauthier, Pharm.D....
www.idstewardship.com
December 11, 2024 at 11:47 PM
Reposted by Jon Magnus Johannesson
"Wuhan lab samples hold no close relatives to virus behind COVID"

That should settle it, right? The problem, of course, it won't because we're dealing with conspiracy theories and not scientific inquiry - no amount of additional data will change un-evidenced beliefs.

www.nature.com/articles/d41...
Wuhan lab samples hold no close relatives to virus behind COVID
Shi Zhengli, the virologist at centre of COVID lab-leak theory, reveals coronavirus sequences from Wuhan institute.
www.nature.com
December 6, 2024 at 5:42 PM
Reposted by Jon Magnus Johannesson
This Thanksgiving, let's thank hospitals that use masking during winter respiratory virus season.

Out in JAMA Network Open: Hospital-onset flu, COVID, and RSV rates when 10 Mass Gen Brigham sites stopped universal testing & masking, then restarted staff masking in Jan 2024. 0/🧵 #IDSky #MedSky
November 28, 2024 at 8:27 PM
Reposted by Jon Magnus Johannesson
🆕️🔥 #JAMA
Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel #idsky #hivsky #tbsky #worldaidsday #medsky
jamanetwork.com/journals/jam...
IAS-USA Recommendations: Antiretrovirals for Treatment and Prevention of HIV in Adults
This Special Communication from the International Antiviral Society–USA provides updated 2024 recommendations for HIV treatment and clinical management and HIV prevention.
jamanetwork.com
December 2, 2024 at 3:54 PM
Reposted by Jon Magnus Johannesson
🆕✨Retrospective population-based cohort study examined infection risk after colonization for MRSA,VRE,ESBL& CPE over a 5-year period
For all organisms the highest risk period of progression from colonization to infection was the first 90d #idsky #medsky
academic.oup.com/ofid/advance...
Long-term Risk of Infection Among Patients Colonized with Antimicrobial Resistant Pathogens: A Population-wide Cohort Study
This was a retrospective population-based cohort study that examined infection risk after colonization for MRSA, VRE, ESBL, and CPE over a 5-year period us
academic.oup.com
December 2, 2024 at 8:51 AM
Reposted by Jon Magnus Johannesson
There's still good in this world 🌏 #IDsky 🦋

and by GOOD I mean the CID-STATE-OF-THE-ART REVIEWS

💯 Must-read for General I.D. (if not already done)

«Evaluation and Management of Pelvic Osteomyelitis in Stage IV Pressure Injuries: A Multidisciplinary Collaborative Approach»

doi.org/10.1093/cid/...
November 13, 2024 at 3:42 AM
Reposted by Jon Magnus Johannesson
About 13 years ago, we started a company called Complexly so we could make SciShow and Crash Course.

That team has grown into a company of 80+ people, who have worked incredibly hard to create 9,000+ videos that are each researched, fact-checked, and available for free.
November 21, 2024 at 10:12 PM
Reposted by Jon Magnus Johannesson
🆕️⚡️⚡️Non-bacterial thrombotic endocarditis (NBTE), formerly recognized as marantic endocarditis, represents a rare cardiovascular pathology intricately linked with hypercoagulable states, notably malignancy and autoimmune disorders. #idsky #idxposts
academic.oup.com/eurheartj/ar...
Non-bacterial thrombotic endocarditis: a clinical and pathophysiological reappraisal
Abstract. Non-bacterial thrombotic endocarditis (NBTE), formerly recognized as marantic endocarditis, represents a rare cardiovascular pathology intricatel
academic.oup.com
November 21, 2024 at 12:25 AM
Reposted by Jon Magnus Johannesson
Hi #IDSky! Febrile is a cultured podcast about all things ID. We talk about clinical reasoning, diagnostics, abxs, and other interesting topics! 🦠 We love showcasing trainees and ID clinicians, and we cover both adult+pediatric topics/cases. We're ~4 years old and sponsored by @idsainfo.bsky.social
febrile – A Cultured Podcast About All Things Infectious Disease
febrilepodcast.com
November 18, 2024 at 3:20 PM
Reposted by Jon Magnus Johannesson
Health officials in California have confirmed the first case of mpox clade I in the US. Patient is a returning traveller's who traveled to eastern Africa. This is not unexpected because the world is interconnected and there are ongoing outbreaks of clade I mpox in Africa.
apnews.com/article/mpox...
US health officials report 1st case of new form of mpox in a traveler
Health officials say they have confirmed the first U.S. case of a new form of mpox that was first seen in eastern Congo.
apnews.com
November 16, 2024 at 8:18 PM
Reposted by Jon Magnus Johannesson
Excellent 🆕️🔥review #CMR
"There is not a “one size fits all” laboratory approach for the detection of bacteria with carbapenemases, and institutions need to determine what fits best with the goals of their antimicrobial stewardship & IP&C programs" #idsky
journals.asm.org/doi/10.1128/...
Laboratory detection of carbapenemases among Gram-negative organisms | Clinical Microbiology Reviews
SUMMARYThe carbapenems remain some of the most effective options available for treating patients with serious infections due to Gram-negative bacteria. Carbapenemases are enzymes that hydrolyze carbapenems and are the primary method driving carbapenem ...
journals.asm.org
November 15, 2024 at 6:45 PM