John “Jack” Flores, MD
@jmfloresmd.bsky.social
4th year MedPeds Infectious Diseases fellow at University of Chicago, ID lover of all ages. 🦠🧫🩺 Father of two 🧒 and one 🐶 Go Irish ☘️
Reposted by John “Jack” Flores, MD
Univ of Chicago PedsID trainees and graduates representing at #IDWeek2025
October 21, 2025 at 7:50 PM
Univ of Chicago PedsID trainees and graduates representing at #IDWeek2025
Reposted by John “Jack” Flores, MD
Increased Reporting of Infants Born with Congenital Syphilis to a Local Department of Public Health: A Quality Improvement Project
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Increased Reporting of Infants Born with Congenital Syphilis to a Local Department of Public Health: A Quality Improvement Project
In this quality improvement project, we successfully improved the reporting of infants diagnosed with and treated for congenital syphilis with non-reactive
bit.ly
October 8, 2025 at 7:53 PM
Increased Reporting of Infants Born with Congenital Syphilis to a Local Department of Public Health: A Quality Improvement Project
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Increased Reporting of Infants Born with Congenital Syphilis to a Local Department of Public Health: A Quality Improvement Project url: academic.oup.com/ofid/article...
Had a LOT of fun with this one. Made me rethink epi of CS and if we are under (or over?) identifying certain groups. #ID #IDsky
Had a LOT of fun with this one. Made me rethink epi of CS and if we are under (or over?) identifying certain groups. #ID #IDsky
Validate User
academic.oup.com
September 30, 2025 at 8:12 PM
Increased Reporting of Infants Born with Congenital Syphilis to a Local Department of Public Health: A Quality Improvement Project url: academic.oup.com/ofid/article...
Had a LOT of fun with this one. Made me rethink epi of CS and if we are under (or over?) identifying certain groups. #ID #IDsky
Had a LOT of fun with this one. Made me rethink epi of CS and if we are under (or over?) identifying certain groups. #ID #IDsky
Reposted by John “Jack” Flores, MD
My adult daughter Rachel works everyday, pays taxes, loves going to movies with her friends, and listens to awful (IMO) music.
Our U.S. Dept HHS has lost all of its humanity, compassion, and intellectual curiosity
Our U.S. Dept HHS has lost all of its humanity, compassion, and intellectual curiosity
April 17, 2025 at 11:22 AM
My adult daughter Rachel works everyday, pays taxes, loves going to movies with her friends, and listens to awful (IMO) music.
Our U.S. Dept HHS has lost all of its humanity, compassion, and intellectual curiosity
Our U.S. Dept HHS has lost all of its humanity, compassion, and intellectual curiosity
I feel like I’ve met a milestone for any infectious disease trainee or provider — contribute to a MMWR ✅ . Really interesting trending and observing unexpected findings of our CNS syphilis cohort in Chicago Illinois.
www.cdc.gov/mmwr/volumes...
www.cdc.gov/mmwr/volumes...
Notes from the Field: Neurosyphilis ...
This report describes neurosyphilis, ocular syphilis ...
www.cdc.gov
March 13, 2025 at 5:50 PM
I feel like I’ve met a milestone for any infectious disease trainee or provider — contribute to a MMWR ✅ . Really interesting trending and observing unexpected findings of our CNS syphilis cohort in Chicago Illinois.
www.cdc.gov/mmwr/volumes...
www.cdc.gov/mmwr/volumes...
Reposted by John “Jack” Flores, MD
In the current political climate, many misunderstand/misrepresent NIH "indirect costs", which cover facility and administrative costs essential for research
Here's a video that explains what F&A expenses cover, how they are determined, and why they are essential
www.youtube.com/watch?v=NtqK...
Here's a video that explains what F&A expenses cover, how they are determined, and why they are essential
www.youtube.com/watch?v=NtqK...
March 8, 2025 at 12:59 PM
In the current political climate, many misunderstand/misrepresent NIH "indirect costs", which cover facility and administrative costs essential for research
Here's a video that explains what F&A expenses cover, how they are determined, and why they are essential
www.youtube.com/watch?v=NtqK...
Here's a video that explains what F&A expenses cover, how they are determined, and why they are essential
www.youtube.com/watch?v=NtqK...
Reposted by John “Jack” Flores, MD
Dear #medsky Together we can help patients understand the importance of vaccines. No matter your specialty, please start talking about vaccines at every visit. Love, #idsky
www.cidrap.umn.edu/influenza-va...
www.cidrap.umn.edu/influenza-va...
Information, clinician advice may be key to boosting vaccines in older people
www.cidrap.umn.edu
February 25, 2025 at 3:33 PM
Dear #medsky Together we can help patients understand the importance of vaccines. No matter your specialty, please start talking about vaccines at every visit. Love, #idsky
www.cidrap.umn.edu/influenza-va...
www.cidrap.umn.edu/influenza-va...
Reposted by John “Jack” Flores, MD
Doxycycline postexposure prophylaxis for bacterial STIs: Prescribing patterns, use, short-term outcomes among 2083 patients in a Los Angeles Federally Qualified Health Care Program, and implications for widespread use.
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Doxycycline postexposure prophylaxis for bacterial STIs: Prescribing patterns, use, short-term outcomes among 2083 patients in a Los Angeles Federally Qualified Health Care Program, and implications for widespread use.
Rates of bacterial sexually transmitted infections (STIs) have risen dramatically over the past decades. Doxycycline postexposure prophylaxis (DP) is a novel intervention to prevent bacterial STIs. Recent randomized controlled clinical trials reported high DP efficacy at preventing syphilis and chlamydia in cisgender men who have sex with men (MSM) and transgender women.
buff.ly
February 20, 2025 at 10:11 PM
Doxycycline postexposure prophylaxis for bacterial STIs: Prescribing patterns, use, short-term outcomes among 2083 patients in a Los Angeles Federally Qualified Health Care Program, and implications for widespread use.
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Had a great time assembling this DoxyPEP review with @anuhazramd.bsky.social , one more step towards reducing STIs in high risk populations
#IDSky
trebuchet.public.springernature.app/get_content/...
#IDSky
trebuchet.public.springernature.app/get_content/...
trebuchet.public.springernature.app
February 19, 2025 at 5:37 PM
Had a great time assembling this DoxyPEP review with @anuhazramd.bsky.social , one more step towards reducing STIs in high risk populations
#IDSky
trebuchet.public.springernature.app/get_content/...
#IDSky
trebuchet.public.springernature.app/get_content/...
Reposted by John “Jack” Flores, MD
Reposted by John “Jack” Flores, MD
Just publish paper evaluating effects of vaccination on long COVID risks in children/adolescents during Delta/Omicron periods
We found vaccines strongly protected against long COVID-19, and the effect was almost wholly mediated by reduced infection risk
www.sciencedirect.com/science/arti...
We found vaccines strongly protected against long COVID-19, and the effect was almost wholly mediated by reduced infection risk
www.sciencedirect.com/science/arti...
December 9, 2024 at 4:52 PM
Just publish paper evaluating effects of vaccination on long COVID risks in children/adolescents during Delta/Omicron periods
We found vaccines strongly protected against long COVID-19, and the effect was almost wholly mediated by reduced infection risk
www.sciencedirect.com/science/arti...
We found vaccines strongly protected against long COVID-19, and the effect was almost wholly mediated by reduced infection risk
www.sciencedirect.com/science/arti...
Reposted by John “Jack” Flores, MD
I ran @USAID health programs for the last 3 years. Trump’s 90 day Stop Work Order on foreign assistance does serious damage to the world and the US. Examples:🧵
January 26, 2025 at 3:56 PM
I ran @USAID health programs for the last 3 years. Trump’s 90 day Stop Work Order on foreign assistance does serious damage to the world and the US. Examples:🧵
Reposted by John “Jack” Flores, MD
This JAMA Clinical Guidelines Synopsis focuses on the recent CDC guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) to prevent bacterial sexually transmitted infections.
ja.ma/3WxWi3D
#MedSky
ja.ma/3WxWi3D
#MedSky
January 25, 2025 at 5:25 PM
This JAMA Clinical Guidelines Synopsis focuses on the recent CDC guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) to prevent bacterial sexually transmitted infections.
ja.ma/3WxWi3D
#MedSky
ja.ma/3WxWi3D
#MedSky
as someone about to graduate ID fellowship, the NIH price freeze immediately prompted my “how does this affect my k23 application?” But today I realized I’m fortunate to always have clinical medicine to do, as opposed to many community workers and research workers fully dependent on NIH financing.
January 24, 2025 at 6:19 PM
as someone about to graduate ID fellowship, the NIH price freeze immediately prompted my “how does this affect my k23 application?” But today I realized I’m fortunate to always have clinical medicine to do, as opposed to many community workers and research workers fully dependent on NIH financing.
I had a lot of fun riding this one with @anuhazramd.bsky.social , definitely a topic with some controversy, but could be a pivotal move to help reduce the incidence of this (not so) “hidden” syphilis epidemic.
This JAMA Clinical Guidelines Synopsis focuses on the recent CDC guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) to prevent bacterial sexually transmitted infections.
https://ja.ma/41FWRvL
https://ja.ma/41FWRvL
December 19, 2024 at 10:19 PM
I had a lot of fun riding this one with @anuhazramd.bsky.social , definitely a topic with some controversy, but could be a pivotal move to help reduce the incidence of this (not so) “hidden” syphilis epidemic.
Reposted by John “Jack” Flores, MD
This JAMA Clinical Guidelines Synopsis focuses on the recent CDC guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) to prevent bacterial sexually transmitted infections.
https://ja.ma/41FWRvL
https://ja.ma/41FWRvL
December 19, 2024 at 6:00 PM
This JAMA Clinical Guidelines Synopsis focuses on the recent CDC guidelines on use of doxycycline postexposure prophylaxis (doxyPEP) to prevent bacterial sexually transmitted infections.
https://ja.ma/41FWRvL
https://ja.ma/41FWRvL
Reposted by John “Jack” Flores, MD
🔥The ADAPT-Sepsis RCT🔥
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Biomarker-Guided Antibiotic Duration for Patients With Suspected Sepsis
This clinical trial assessed whether treatment protocols for monitoring C-reactive protein or procalcitonin safely reduced the amount of time critically ill adults with suspected sepsis received antib...
jamanetwork.com
December 10, 2024 at 3:39 AM
🔥The ADAPT-Sepsis RCT🔥
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care.
No difference was found in total Abx duration between standard care & daily CRP-guided protocol
CRP failure #idsky #EMIMCC
jamanetwork.com/journals/jam...
Reposted by John “Jack” Flores, MD
Cool analysis restricted to women younger than 25 to isolate the impact of routine HPV vaccination in US women since June 2006.
"HPV vaccination affected the sequential decline in #HPV infection prevalence, cervical cancer incidence, and cervical cancer mortality."
#VaccinesSaveLives #IDSky
"HPV vaccination affected the sequential decline in #HPV infection prevalence, cervical cancer incidence, and cervical cancer mortality."
#VaccinesSaveLives #IDSky
Cervical Cancer Mortality Among US Women Younger Than 25 Years
This study examines trends in cervical cancer mortality in US women aged younger than 25 years before and after the introduction of human papillomavirus vaccines.
jamanetwork.com
December 2, 2024 at 6:50 PM
Cool analysis restricted to women younger than 25 to isolate the impact of routine HPV vaccination in US women since June 2006.
"HPV vaccination affected the sequential decline in #HPV infection prevalence, cervical cancer incidence, and cervical cancer mortality."
#VaccinesSaveLives #IDSky
"HPV vaccination affected the sequential decline in #HPV infection prevalence, cervical cancer incidence, and cervical cancer mortality."
#VaccinesSaveLives #IDSky
Reposted by John “Jack” Flores, MD
Find me a better intervention in medicine.
#VaccinesSaveLives
#VaccinesSaveLives
Many infants and children who are infected with hepatitis B become chronic carriers. Since we have been vaccinating newborns since the 1990s, the number of new cases of hepatitis have decreased. (3/7)
November 22, 2024 at 2:44 PM
Find me a better intervention in medicine.
#VaccinesSaveLives
#VaccinesSaveLives
Reposted by John “Jack” Flores, MD
Author Jason Zucker of Columbia University Irving Medical Center speaks with JAMA Deputy Editor Preeti Malani about the transmission, diagnosis, management, and prevention of mpox.
Listen to the episode: https://ja.ma/48UlfeJ
Listen to the episode: https://ja.ma/48UlfeJ
November 20, 2024 at 10:59 PM
Author Jason Zucker of Columbia University Irving Medical Center speaks with JAMA Deputy Editor Preeti Malani about the transmission, diagnosis, management, and prevention of mpox.
Listen to the episode: https://ja.ma/48UlfeJ
Listen to the episode: https://ja.ma/48UlfeJ
Reposted by John “Jack” Flores, MD
Reposted by John “Jack” Flores, MD
The ID march of shorter treatment is ok continues, this time for bacteremia (not including S. aureus).
FYI, E. coli, Klebsiella, Enterococcus, and CoNS made up > 70% of organisms.
By pathogen breakdown of risk difference emphasizes applicability of these results for GN bacteremia.
FYI, E. coli, Klebsiella, Enterococcus, and CoNS made up > 70% of organisms.
By pathogen breakdown of risk difference emphasizes applicability of these results for GN bacteremia.
November 20, 2024 at 8:31 PM
The ID march of shorter treatment is ok continues, this time for bacteremia (not including S. aureus).
FYI, E. coli, Klebsiella, Enterococcus, and CoNS made up > 70% of organisms.
By pathogen breakdown of risk difference emphasizes applicability of these results for GN bacteremia.
FYI, E. coli, Klebsiella, Enterococcus, and CoNS made up > 70% of organisms.
By pathogen breakdown of risk difference emphasizes applicability of these results for GN bacteremia.
Reposted by John “Jack” Flores, MD
I can't find African Scientists and researchers easily on here. As the second largest continent with 1.3 billion inhabitants our perspectives matter. I'm creating a starterpack to find folks, follow them and amplify them. If you are an African Scientist let me know below so I can add you. Thanks.
November 20, 2024 at 11:08 AM
I can't find African Scientists and researchers easily on here. As the second largest continent with 1.3 billion inhabitants our perspectives matter. I'm creating a starterpack to find folks, follow them and amplify them. If you are an African Scientist let me know below so I can add you. Thanks.
Fun QI study looking and reducing ID fellow burnout. Essentially having more Attending physician presence makes for happier fellows 😀
ir.library.louisville.edu/jwellness/vo...
ir.library.louisville.edu/jwellness/vo...
The Effect of a Structural Wellness Intervention on ID Fellows and Faculty
Introduction: Physician burnout is prevalent amongst Infectious Diseases (ID) physicians and trainees in the United States. There is limited data assessing the impact of structural interventions in re...
ir.library.louisville.edu
November 20, 2024 at 9:13 PM
Fun QI study looking and reducing ID fellow burnout. Essentially having more Attending physician presence makes for happier fellows 😀
ir.library.louisville.edu/jwellness/vo...
ir.library.louisville.edu/jwellness/vo...