Happy 276th birthday Edward Jenner! What a time for vaccination: 154 million lives saved in the last 50 years, tempered with an increase in vaccine preventable diseases across the world, vaccine sceptics in charge in the US, and cuts to overseas aid threatening global immunisation programmes.

Complete First Issue of Journal of Human Immunity is here! JHI is the official #OpenAccess journal of the International Alliance for Primary Immunodeficiency Societies #IAPIDS. Explore new research and the inaugural editorial from our EiC @casanovalab.bsky.social 👉 rupress.org/jhi/issue/1/1

New review @jem.org from Schmitz et al. @macattacklab.bsky.social explores the identification of somatic variants as a cause of #InbornErrorsOfImmunity, including the identification of somatic variants and the mechanisms by which they might lead to immunologic disease. rupress.org/jem/article/...

& pyrin-associated autoinflammation with hypereosinophilia. A section dedicated to current somatic forms of FMF is also developed. Several patients with undifferentiated systemic AIDs/syndrome of undifferentiated recurrent fever

www.jaci-inpractice.org/article/S221...
@jaciinpractice.bsky.social

Review: Spaan, Boisson, and @sethlucianmasters.bsky.social review the known primary disorders of the polyubiquitination pathways in humans that lead to #autoinflammation and/or #immunodeficiency rupress.org/jem/article/...