José Carlos Souto (@jcsouto)
@jcsouto.bsky.social
Médico, autor do livro Uma Dieta Além da Moda;
apreciador de Brahms, Bach, Kurt Atterberg e coisas ainda mais estranhas;
fã de Carl Sagan desde criancinha
apreciador de Brahms, Bach, Kurt Atterberg e coisas ainda mais estranhas;
fã de Carl Sagan desde criancinha
Reposted by José Carlos Souto (@jcsouto)
visual abstract of the trial and results
November 9, 2025 at 3:49 PM
visual abstract of the trial and results
Reposted by José Carlos Souto (@jcsouto)
Quero falar sobre a meta-análise de Dieta Cetogênica na Depressão e na Ansiedade que saiu no @JAMAPsych porque sei que amanhã a PICARETOSFERA inteira vai repercutir e vocês precisam saber o significado desses achados. Segue o fio 🧵. jamanetwork.com/journals/jam...
Ketogenic Diets and Depression and Anxiety
This systematic review and meta-analysis assesses the associations between ketogenic diets and mental health outcomes in adults, with a focus on depressive and anxiety symptoms.
jamanetwork.com
November 6, 2025 at 3:13 PM
Quero falar sobre a meta-análise de Dieta Cetogênica na Depressão e na Ansiedade que saiu no @JAMAPsych porque sei que amanhã a PICARETOSFERA inteira vai repercutir e vocês precisam saber o significado desses achados. Segue o fio 🧵. jamanetwork.com/journals/jam...
Reposted by José Carlos Souto (@jcsouto)
This is a fascinating story.
A Lebanese team published a study showing massive benefits for apple cider vinegar in 2024. People immediately noticed it was problematic, and complained.
BMJ asked the authors for the data, and they sent it through. The study has just been retracted and WOW 1/n
A Lebanese team published a study showing massive benefits for apple cider vinegar in 2024. People immediately noticed it was problematic, and complained.
BMJ asked the authors for the data, and they sent it through. The study has just been retracted and WOW 1/n
September 29, 2025 at 10:51 PM
This is a fascinating story.
A Lebanese team published a study showing massive benefits for apple cider vinegar in 2024. People immediately noticed it was problematic, and complained.
BMJ asked the authors for the data, and they sent it through. The study has just been retracted and WOW 1/n
A Lebanese team published a study showing massive benefits for apple cider vinegar in 2024. People immediately noticed it was problematic, and complained.
BMJ asked the authors for the data, and they sent it through. The study has just been retracted and WOW 1/n
Reposted by José Carlos Souto (@jcsouto)
New piece out - do soft drinks give you depression?
Probably not. The evidence is SUPER weak. gidmk.substack.com/p/soft-drink...
Probably not. The evidence is SUPER weak. gidmk.substack.com/p/soft-drink...
Soft Drinks Probably Aren't Making You Depressed
Why soda/pop/soft drinks probably aren't causing depression.
gidmk.substack.com
September 26, 2025 at 4:36 AM
New piece out - do soft drinks give you depression?
Probably not. The evidence is SUPER weak. gidmk.substack.com/p/soft-drink...
Probably not. The evidence is SUPER weak. gidmk.substack.com/p/soft-drink...
Reposted by José Carlos Souto (@jcsouto)
10/n Regardless, all of this fuss and noise about soft drinks and depression comes from a cross-sectional study that only assessed soft drink consumption at one time point and did not follow-up patients at all.
Which is absurd.
Which is absurd.
September 26, 2025 at 1:42 AM
10/n Regardless, all of this fuss and noise about soft drinks and depression comes from a cross-sectional study that only assessed soft drink consumption at one time point and did not follow-up patients at all.
Which is absurd.
Which is absurd.
Reposted by José Carlos Souto (@jcsouto)
4/n This is straightforwardly meaningless scientifically. It was a cross-sectional survey of food consumption with some gut microbiome assessment thrown in. According to their methods, the only covariates included in the logistic model here were age and sex.
September 26, 2025 at 1:42 AM
4/n This is straightforwardly meaningless scientifically. It was a cross-sectional survey of food consumption with some gut microbiome assessment thrown in. According to their methods, the only covariates included in the logistic model here were age and sex.
Reposted by José Carlos Souto (@jcsouto)
Science can be such a headache sometimes.
This study has hit the headlines because the authors claim that it shows that soft drinks cause people to be depressed by negatively impacting their gut microbiome.
Several BIG issues with this 1/n
This study has hit the headlines because the authors claim that it shows that soft drinks cause people to be depressed by negatively impacting their gut microbiome.
Several BIG issues with this 1/n
September 26, 2025 at 1:42 AM
Science can be such a headache sometimes.
This study has hit the headlines because the authors claim that it shows that soft drinks cause people to be depressed by negatively impacting their gut microbiome.
Several BIG issues with this 1/n
This study has hit the headlines because the authors claim that it shows that soft drinks cause people to be depressed by negatively impacting their gut microbiome.
Several BIG issues with this 1/n
Groundbreaking! @gidmk.bsky.social and @slate.com prove that you can cover an academic study by actually *reading* it, not just regurgitating every breathless bullet point from the press release...
This is what science journalism should look like 👇
slate.com/technology/2...
This is what science journalism should look like 👇
slate.com/technology/2...
Scientists Tested the Link Between Artificial Sweetener and Cognitive Decline. Here’s What You Need to Know.
Scientists tested for links between artificial sweeteners and cognitive decline.
slate.com
September 19, 2025 at 1:39 AM
Como escrevi na semana passada, esse estudo altamente problemático jamais permitiria sugerir que adoçantes em geral sejam deletérios para o cérebro, muito menos adoçantes específicos.
A reprodução totalmente acrítica pela mídia é algo que precisa ser repensado
A reprodução totalmente acrítica pela mídia é algo que precisa ser repensado
Groundbreaking! @gidmk.bsky.social and @slate.com prove that you can cover an academic study by actually *reading* it, not just regurgitating every breathless bullet point from the press release...
This is what science journalism should look like 👇
slate.com/technology/2...
This is what science journalism should look like 👇
slate.com/technology/2...
Scientists Tested the Link Between Artificial Sweetener and Cognitive Decline. Here’s What You Need to Know.
Scientists tested for links between artificial sweeteners and cognitive decline.
slate.com
September 19, 2025 at 1:38 AM
Como escrevi na semana passada, esse estudo altamente problemático jamais permitiria sugerir que adoçantes em geral sejam deletérios para o cérebro, muito menos adoçantes específicos.
A reprodução totalmente acrítica pela mídia é algo que precisa ser repensado
A reprodução totalmente acrítica pela mídia é algo que precisa ser repensado
Reposted by José Carlos Souto (@jcsouto)
Groundbreaking! @gidmk.bsky.social and @slate.com prove that you can cover an academic study by actually *reading* it, not just regurgitating every breathless bullet point from the press release...
This is what science journalism should look like 👇
slate.com/technology/2...
This is what science journalism should look like 👇
slate.com/technology/2...
Scientists Tested the Link Between Artificial Sweetener and Cognitive Decline. Here’s What You Need to Know.
Scientists tested for links between artificial sweeteners and cognitive decline.
slate.com
September 18, 2025 at 11:10 PM
Groundbreaking! @gidmk.bsky.social and @slate.com prove that you can cover an academic study by actually *reading* it, not just regurgitating every breathless bullet point from the press release...
This is what science journalism should look like 👇
slate.com/technology/2...
This is what science journalism should look like 👇
slate.com/technology/2...
Reposted by José Carlos Souto (@jcsouto)
We've all had this conversation before:
"Dude, we both agree this is red... but how do I know what I see as red is what you see as red? Maybe you see red as I see blue."
Mind blown lol.
But we finally have some research that sheds light (and color) on the issue. (Thread)
"Dude, we both agree this is red... but how do I know what I see as red is what you see as red? Maybe you see red as I see blue."
Mind blown lol.
But we finally have some research that sheds light (and color) on the issue. (Thread)
September 9, 2025 at 6:53 PM
We've all had this conversation before:
"Dude, we both agree this is red... but how do I know what I see as red is what you see as red? Maybe you see red as I see blue."
Mind blown lol.
But we finally have some research that sheds light (and color) on the issue. (Thread)
"Dude, we both agree this is red... but how do I know what I see as red is what you see as red? Maybe you see red as I see blue."
Mind blown lol.
But we finally have some research that sheds light (and color) on the issue. (Thread)
O artigo sobre adoçantes e declínio cognitivo, além dos problemas que já citei ontem aqui e no último episódio do podcast Comida sem Filtro, está repleto de erros estatísticos, se vê nesse fio
As noted by @carlmc.bsky.social, one odd pattern in these results is that ALL the estimates and confidence interval bounds are multiples of 0.008
What could explain that? 🤔
What could explain that? 🤔
September 8, 2025 at 11:15 AM
O artigo sobre adoçantes e declínio cognitivo, além dos problemas que já citei ontem aqui e no último episódio do podcast Comida sem Filtro, está repleto de erros estatísticos, se vê nesse fio
Reposted by José Carlos Souto (@jcsouto)
It’s really worrying that it takes a political scientist to point out all these irregularities in a paper that is picked up to such an extent by the press — reviewers, science editors, anyone listening? Anyone bothered to ask for the underlying data & code?
As noted by @carlmc.bsky.social, one odd pattern in these results is that ALL the estimates and confidence interval bounds are multiples of 0.008
What could explain that? 🤔
What could explain that? 🤔
September 6, 2025 at 8:35 AM
It’s really worrying that it takes a political scientist to point out all these irregularities in a paper that is picked up to such an extent by the press — reviewers, science editors, anyone listening? Anyone bothered to ask for the underlying data & code?
1/
👉 Headlines are spreading about a new study (neurology.org/doi/10.1212/...) claiming that 7 artificial sweeteners are linked to accelerated cognitive decline.
Most headlines use causal language and scary numbers.
But the study is VERY problematic. 🧵
👉 Headlines are spreading about a new study (neurology.org/doi/10.1212/...) claiming that 7 artificial sweeteners are linked to accelerated cognitive decline.
Most headlines use causal language and scary numbers.
But the study is VERY problematic. 🧵
Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline | Neurology
Background and ObjectivesConsumption of low- and no-calorie sweeteners (LNCSs) has been associated with adverse
health outcomes. However, little is known about the association between consumption
of L...
neurology.org
September 8, 2025 at 8:53 AM
1/
👉 Headlines are spreading about a new study (neurology.org/doi/10.1212/...) claiming that 7 artificial sweeteners are linked to accelerated cognitive decline.
Most headlines use causal language and scary numbers.
But the study is VERY problematic. 🧵
👉 Headlines are spreading about a new study (neurology.org/doi/10.1212/...) claiming that 7 artificial sweeteners are linked to accelerated cognitive decline.
Most headlines use causal language and scary numbers.
But the study is VERY problematic. 🧵
Reposted by José Carlos Souto (@jcsouto)
Man, I should really stop opening cans of Pepsi Max by slamming them into my forehead
September 8, 2025 at 3:29 AM
Man, I should really stop opening cans of Pepsi Max by slamming them into my forehead
1/
👉 Proliferam manchetes sobre um novo estudo (neurology.org/doi/10.1212/...) que alega que 7 adoçantes artificiais estão associados com declínio cognitivo acelerado.
📰 Quase todas usam linguagem causal e números assustadores.
Mas o estudo é BEM problemático. 🧵
👉 Proliferam manchetes sobre um novo estudo (neurology.org/doi/10.1212/...) que alega que 7 adoçantes artificiais estão associados com declínio cognitivo acelerado.
📰 Quase todas usam linguagem causal e números assustadores.
Mas o estudo é BEM problemático. 🧵
Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline | Neurology
Background and ObjectivesConsumption of low- and no-calorie sweeteners (LNCSs) has been associated with adverse
health outcomes. However, little is known about the association between consumption
of L...
neurology.org
September 7, 2025 at 12:17 PM
1/
👉 Proliferam manchetes sobre um novo estudo (neurology.org/doi/10.1212/...) que alega que 7 adoçantes artificiais estão associados com declínio cognitivo acelerado.
📰 Quase todas usam linguagem causal e números assustadores.
Mas o estudo é BEM problemático. 🧵
👉 Proliferam manchetes sobre um novo estudo (neurology.org/doi/10.1212/...) que alega que 7 adoçantes artificiais estão associados com declínio cognitivo acelerado.
📰 Quase todas usam linguagem causal e números assustadores.
Mas o estudo é BEM problemático. 🧵
Reposted by José Carlos Souto (@jcsouto)
A new expression of concern was published on this randomized clinical trial of cinnamon for diabetes.
The study itself has been cited, according to Google, 1,700 times.
I first complained about it in 2023, so let me tell you the story of one of the most problematic papers I've come across 1/n
The study itself has been cited, according to Google, 1,700 times.
I first complained about it in 2023, so let me tell you the story of one of the most problematic papers I've come across 1/n
August 25, 2025 at 3:30 AM
A new expression of concern was published on this randomized clinical trial of cinnamon for diabetes.
The study itself has been cited, according to Google, 1,700 times.
I first complained about it in 2023, so let me tell you the story of one of the most problematic papers I've come across 1/n
The study itself has been cited, according to Google, 1,700 times.
I first complained about it in 2023, so let me tell you the story of one of the most problematic papers I've come across 1/n
August 20, 2025 at 11:43 PM
Editorial do Estadão de hoje. Lembrando que trata-se de um jornal *conservador*. O conservadorismo precisa se distanciar do golpismo e do entreguismo. Ainda há tempo
August 13, 2025 at 10:41 AM
Editorial do Estadão de hoje. Lembrando que trata-se de um jornal *conservador*. O conservadorismo precisa se distanciar do golpismo e do entreguismo. Ainda há tempo
MAGA / PL / NOVO
July 28, 2025 at 12:08 AM
MAGA / PL / NOVO
🔥
July 18, 2025 at 12:02 PM
🔥
Reposted by José Carlos Souto (@jcsouto)
Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...
Food Intelligence by Julia Belluz, Kevin Hall, PhD: 9780593332306 | PenguinRandomHouse.com: Books
The essential guide for understanding what you’re eating, and the forces that are driving you to eat it. Nutrition isn’t rocket science; it’s harder. There are new diet fads, bold...
www.penguinrandomhouse.com
July 16, 2025 at 9:53 AM
Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...
A direita brasileira tem agora uma oportunidade *única* de imitar a direita europeia e criar um CORDÃO SANITÁRIO para isolar o extremismo golpista.
Não precisa ser petista nem esquerdista. Mas não pode vender o país e rastejar pra salvar Grande Líder.
Editorial do Estadão:
Não precisa ser petista nem esquerdista. Mas não pode vender o país e rastejar pra salvar Grande Líder.
Editorial do Estadão:
July 15, 2025 at 7:33 PM
A direita brasileira tem agora uma oportunidade *única* de imitar a direita europeia e criar um CORDÃO SANITÁRIO para isolar o extremismo golpista.
Não precisa ser petista nem esquerdista. Mas não pode vender o país e rastejar pra salvar Grande Líder.
Editorial do Estadão:
Não precisa ser petista nem esquerdista. Mas não pode vender o país e rastejar pra salvar Grande Líder.
Editorial do Estadão: