Jaeda Coutinho-Budd
LightNews LightNews
jcoutinhobudd.bsky.social
Jaeda Coutinho-Budd
@jcoutinhobudd.bsky.social
550 followers 340 following 12 posts
Assistant Professor @ UVA Neuroscience & BIG Center. Glial biologist and Neuroscientist. 🪰🧠
Posts Replies Media Videos
Reposted by Jaeda Coutinho-Budd
docsirianni.bsky.social
Unreal, the impact this is having on scientists. I spent over 700 hrs writing 4 grants submitted Apr-Sept that *might* have been funded next Apr; 2 abt to be 3 apps missed review bc of shutdown. In normal times takes 9-24 mo to get a grant funded. No hope for labs like mine. Literally no hope.
drrabbithole.bsky.social Dr. Rabbithole @drrabbithole.bsky.social · 17d
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
November 13, 2025 at 1:58 PM
Reposted by Jaeda Coutinho-Budd
drrabbithole.bsky.social
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
November 13, 2025 at 1:25 PM
Reposted by Jaeda Coutinho-Budd
bbholmes.bsky.social
Our new paper is out! Amyloid plaques switch on microglial GPC4, increasing neuronal tau uptake & toxicity—defining an amyloid→glia→tau pathway & a potential drug target. Pleasure to work with our collaborator @jcoutinhobudd.bsky.social. doi.org/10.1186/s130...

#Alzheimers #Glia #Tau #Amyloid
β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity - Molecular Neurodegeneration
To define how Aβ pathology alters microglia function in Alzheimer’s disease, we profiled the microglia surfaceome following treatment with Aβ fibrils. Our findings reveal that Aβ-associated human micr...
doi.org
September 8, 2025 at 1:18 AM
Reposted by Jaeda Coutinho-Budd
aguler.bsky.social
🚨 We’re hiring! 🧪 @uvabio.bsky.social
UVA Biology is recruiting multiple tenure-track Assistant Professors in neuroscience as part of a $75M Brain & Neuroscience Initiative. 🧠
Apply by Oct 15, 2025. Start Aug 2026.
👉 apply.interfolio.com/172892
#Neuroscience #FacultyJobs #NeuroJobs #Biology #UVA
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 4, 2025 at 9:02 PM
Reposted by Jaeda Coutinho-Budd
molneurodegen.bsky.social
β-Amyloid induces #microglial expression of GPC4 and #APOE leading to increased neuronal tau pathology and toxicity

Brandon B. Holmes, Thaddeus K. Weigel, Jesseca M. Chung...James A. Wells #AlzheimersDisease #drosophila #amyloid #microglia @ucsanfrancisco.bsky.social

bit.ly/3HXP98J
β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity - Molecular Neurodegeneration
To define how Aβ pathology alters microglia function in Alzheimer’s disease, we profiled the microglia surfaceome following treatment with Aβ fibrils. Our findings reveal that Aβ-associated human micr...
molecularneurodegeneration.biomedcentral.com
August 29, 2025 at 4:01 PM
jcoutinhobudd.bsky.social
It was fantastic to work with Dr. Holmes and colleagues to integrate work from flies to humans in Alzheimer’s

molecularneurodegeneration.biomedcentral.com/articles/10....
β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity - Molecular Neurodegeneration
To define how Aβ pathology alters microglia function in Alzheimer’s disease, we profiled the microglia surfaceome following treatment with Aβ fibrils. Our findings reveal that Aβ-associated human micr...
molecularneurodegeneration.biomedcentral.com
August 29, 2025 at 6:06 PM
Reposted by Jaeda Coutinho-Budd
peiferlabunc.bsky.social
The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
Dear Fly Community, In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled. The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC). Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options. To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum). To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu… https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase Our immediate goals are: 1. To maintain core curation activities and keep the FlyBase website online 2. To complete integration with the Alliance of Genome Resources (The Alliance). Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data. At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise. Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028. We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide. Sincerely, The FlyBase Team
August 23, 2025 at 12:18 PM
Reposted by Jaeda Coutinho-Budd
joshdubnau.bsky.social
Fly folk:

The Amazing and essential @flybase.bsky.social is in existential need due to Trump termination of the grant that supports this vital resource.

Please donate to help keep Flybase alive. I just did. Info here on how to make a tax deductible donation:

wiki.flybase.org/wiki/FlyBase...
FlyBase:Contribute to FlyBase - FlyBase Wiki
wiki.flybase.org
August 22, 2025 at 7:22 PM
jcoutinhobudd.bsky.social
So excited this is finally out! 🎉

doi.org/10.1002/glia...
August 6, 2025 at 3:00 PM
Reposted by Jaeda Coutinho-Budd
tuthill.bsky.social
i wrote an essay for @thetransmitter.bsky.social about what it feels like to serve on an NIH grant review panel (study section) right now

www.thetransmitter.org/craft-and-ca...
Fear and loathing on study section: Reviewing grant proposals while the system is burning
As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.
www.thetransmitter.org
July 14, 2025 at 6:49 PM
Reposted by Jaeda Coutinho-Budd
itsafronomics.bsky.social
If your representatives are not REPRESENTING YOU and making life harder for you, you need to fire them. That's it.
July 1, 2025 at 8:21 PM
Reposted by Jaeda Coutinho-Budd
sharbat.bsky.social
WOW, WE'RE DOING TARDIGRADE NEUROSCIENCE? Noice!
www.nature.com/articles/d41...
Tardigrade-obsessed: meet the researchers trying to turn water bears into neuroscience models
For water-bear enthusiasts, it’s the creature’s legs that make it stand out.
www.nature.com
June 30, 2025 at 8:33 AM
jcoutinhobudd.bsky.social
The man behind me in the grocery line just told the cashier to continue ringing through to his stuff and he was gonna pay for mine. It was literally $200. He said that he’s been going through some stuff lately and he just wants to do something good. 🥹

Reminder: there is still good in this world. ❤️🙏
June 29, 2025 at 4:02 PM
Reposted by Jaeda Coutinho-Budd
aaup.org
“Campus leaders need to understand that their capitulations and concessions only further empower the greatest threat to higher education since the Red Scare, if not earlier.”

(The AAUP contends that this moment is far worse.)

Act Now.

Never Cave.

#DefendHigherEd
June 28, 2025 at 3:55 PM
Reposted by Jaeda Coutinho-Budd
mathewkiang.com
Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...
Call for 20 Assistant Professor positions
Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...
ki.se
June 25, 2025 at 2:56 PM
Reposted by Jaeda Coutinho-Budd
kairyssdal.bsky.social
Wow. Just wow.

University of Virginia President Resigns Under Pressure From Trump Administration www.nytimes.com/2025/06/27/u...
University of Virginia President Resigns Under Pressure From Trump Administration
www.nytimes.com
June 27, 2025 at 5:05 PM
Reposted by Jaeda Coutinho-Budd
hansonmark.bsky.social
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
marcsdionne.bsky.social Marc Dionne @marcsdionne.bsky.social · Jun 3
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 5:20 PM
Reposted by Jaeda Coutinho-Budd
singhvilabglia.bsky.social
Happy to present a single cell atlas of ALL glia, in BOTH sexes of an animal (in vivo validated!)! Fab work by postdoc @glia-maria.bsky.social, team, & collaboration with @manusetty.bsky.social . Find insights into glia, new analytics and ML models, and browse our companion website (wormglia.org)
React App
Web site created using create-react-app
wormglia.org
June 16, 2025 at 9:16 PM
Reposted by Jaeda Coutinho-Budd
liddelowsa.bsky.social
Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity
June 15, 2025 at 4:20 PM
Reposted by Jaeda Coutinho-Budd
luckytran.com
"We are speaking on behalf of hundreds of NIH staff who are standing up together to say: WE DISSENT.

I am so scared about doing this but I am trying to be brave for my kids because it's only gonna get harder to speak up."

Thank you to Dr. Jenna Norton and NIH scientists for your courage!
June 9, 2025 at 5:25 PM
Reposted by Jaeda Coutinho-Budd
jeremymberg.bsky.social
ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 6:03 PM
Reposted by Jaeda Coutinho-Budd
jamesrossneuro.bsky.social
Know anyone looking for a lab specialist/technician job? The Ross lab is hiring! This position will help the lab with our research on anti-tumor immunity in high-grade glioma. Incredible training environment!!
🐭🔬🧪🦠🧠

jobs.virginia.edu/us/en/job/R0...
Lab Tech/Specialist Varying Levels - Neuroscience in Charlottesville, Virginia, United States of America | Research at University of Virginia
Apply for Lab Tech/Specialist Varying Levels - Neuroscience job with University of Virginia in Charlottesville, Virginia, United States of America. Research at University of Virginia
jobs.virginia.edu
April 17, 2025 at 10:52 PM
Reposted by Jaeda Coutinho-Budd
kevinh-phd.bsky.social
After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.
April 16, 2025 at 9:00 PM
Reposted by Jaeda Coutinho-Budd
carlzimmer.com
Nature has a story on science tattoos, in which they quoted me about my 2011 book, Science Ink (still in print!) www.nature.com/articles/d41...
Science on our sleeves: the research that inspires our tattoos
Inked scientists choose scientific images to mark career accomplishments and illustrate their research passion.
www.nature.com
April 16, 2025 at 7:26 PM
Reposted by Jaeda Coutinho-Budd
jdpereira.bsky.social
I wonder, for those of us on a tenure clock, how will this situation factor in?

We’re not playing the same game we set out to play.
a man in a suit and tie with nbc written on the bottom right
ALT: a man in a suit and tie with nbc written on the bottom right
media.tenor.com
April 13, 2025 at 1:01 PM