Juan C. Landoni 🔬
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jclandoni.bsky.social
Juan C. Landoni 🔬
@jclandoni.bsky.social
Mitochondriac 🔬 Postdoc @EPFL Manley lab of Experimental Biophysics 🧪 Ph.D. @HelsinkiUni 🇦🇷🇫🇮🇪🇺🇨🇭🏳️‍🌈 (he/él)

linktr.ee/jclandoni
Smartest booth luring strategy I've seen: a pro barista on site 🤯
Drop the free pens. Science runs on espresso ☕️
November 6, 2025 at 12:24 PM
That's a wrap on a much-needed family vacay, thank you Costa Rica for your incredible nature 🌋🦥🏞️🐠🐡🐒🦈, now back to our regularly scheduled programming 🔬
October 27, 2025 at 3:31 PM
#Writing with a view 🤩
October 21, 2025 at 1:23 AM
Still buzzing from the incomparable @embl.org #SeeingisBelieving conference! 🔬
Great science and truly amazing people, thanks everyone!
#EESImaging
October 14, 2025 at 7:32 PM
"Who needs a 30x zoom anyway?"
I just found out the answer 🌙🤩
September 7, 2025 at 7:15 PM
Proof that I also care about other organelles 😁🔬
🟢 #ER 👉👈 #Mitochondria 🟣
August 26, 2025 at 3:04 PM
Trying my hand at HTML/CSS using @github.com hosting for a new personal website 💻 Highly recommend!

jclandoni.github.io

Comments/tips welcome (should look nicer on desktop but mobile should work too).
August 25, 2025 at 11:52 AM
Still not a bean 🫘

#Mitochondria (and friends) in #retina cells 👀 EM tomography 🔬🧪
August 22, 2025 at 10:57 AM
So excited to follow the opening symposium of #SWAN 🦢[Sustainable Wellbeing Across Lifespan] at @helsinki.fi today! Congrats to @awartiovaara.bsky.social and all members for the exciting ongoing and future reseach!

#mitochondria #metabolism #aging #health
August 20, 2025 at 12:43 PM
August 19, 2025 at 2:43 PM
Order, chaos & complexity

#Mitochondria in #muscle cells 💪🔬, color-coded by 3D depth 🧪
August 19, 2025 at 2:42 PM
In case you haven't heard, #Argentinian scientists are live-streaming their deep-sea mission with real-time interactive commentary.

It's genius, mesmerising, and triggering huge public interest and support for #science funding 🐙🧪 And the memes are great! #CONICET #MarDelPlataCanyon
August 6, 2025 at 8:32 AM
The magic of the live #mito straight from the microscope 🔬 for #FluorescenceFriday - brought to you by #SYBRgold 🟢 and #PKMO 🟠 @spirochrome.com

@carolinklose.bsky.social @lycasworks.bsky.social
February 21, 2025 at 10:23 AM
TL;DR: #Mitochondria pearling is a spontaneous, frequent, and reversible biophysical event🔄 Orchestrated by cristae architecture, it drives the fundamental disaggregation and distribution of #mtDNA nucleoids. 🧬

biorxiv.org/content/10.1...
December 23, 2024 at 4:37 PM
The amazing @jmacuada.bsky.social found that cristae architecture plays a dual role: cristae density regulates pearling frequency/reversibility and maintains nucleoid spacing🧩 Without either, nucleoids form long clusters—or “nucleotes”!
December 23, 2024 at 4:37 PM
@gavsturm.bsky.social @wallaceucsf.bsky.social and friends at #Calico explored how mitos pearl in cells, revealing a unifying biophysical mechanism 🧪 Their herculean work sheds light on the myriad ways mitochondria can pearl! biorxiv.org/content/10.1...
December 23, 2024 at 4:37 PM
Lo and behold, #pearling “forces” nucleoids into specific spots, and they typically stay there after #mito recovery. It even splits large nucleoid clusters, mediating their segregation! 🎥 by STED wizard @lycasworks.bsky.social 🔬 biorxiv.org/content/10.1...
December 23, 2024 at 4:37 PM
Solution? Mitochondrial #pearling!📿Long mitos can spontaneously, frequently, and reversibly form “beads-on-a-string” structures, seen across evolution (Check your movies—you’ll spot it! And the regular wavelength of pearling is suspiciously similar to nucleoid positioning 👀
December 23, 2024 at 4:37 PM
#Mitochondria DNA is packaged in nucleoids, distributed at remarkably regular distances along the #mito network 🕸️ But nucleoids need to be separated after replication and positioned—a tough task in a crowded matrix with dense cristae and without a transport mechanism 🤔
December 23, 2024 at 4:37 PM
Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
December 23, 2024 at 4:37 PM
Delicious mini-banquet and panettone for the last faculty council meeting of the year #EPFL #SB 🧪
December 2, 2024 at 8:08 PM
I love a #shiny app to explore a big dataset. This one, however, came with an unexpected extra challenge...

#Wingdings as a font is a strong choice 😅

#🕈︎♓︎■︎♑︎♎︎♓︎■︎♑︎⬧︎ @rstats-sky.bsky.social #Rstats #SciSky #AcademicSky 🧪
November 30, 2024 at 11:15 AM
A tragically failed staining for #FluorescenceFriday, but a fun opportunity to play with @kwolbachia.bsky.social awesome LUTs!

Can anyone recognize the structures in this bouquet? 💐

#SciSky #AcademicSky #FluorescentFriday 🔬 🧪 🐡 🦑
November 29, 2024 at 3:59 PM
Post a photo of yourself from a different era - My highschool mane ft. chemistry olympiads 💚🧪⚗️🧑‍🔬
November 28, 2024 at 2:55 PM
Manuscript #review with a view 🏰

🧪 #SciSky #AcademicSky
#ChateaudeChillon #Montreux
November 24, 2024 at 2:26 PM