Jarod
@jarodrutledge.bsky.social
neuroimmunologist/computational biologist turned serial founder turned VC. I care about individual health, agency, and capacity. proudly backing sci-fi futures, trying to avert near-term apocalypses.
Excited this study is finally out, congrats to my good friend Hamilton for the quick follow up in UKBB from our original Nature paper, validating and expanding our initial set of findings. Brains and blood!
The immune system and brain are uniquely associated with healthspan and longevity, the latest insights from organ clock proteomics
@naturemedicine.bsky.social
nature.com/articles/s41...
@naturemedicine.bsky.social
nature.com/articles/s41...
July 9, 2025 at 4:59 PM
Excited this study is finally out, congrats to my good friend Hamilton for the quick follow up in UKBB from our original Nature paper, validating and expanding our initial set of findings. Brains and blood!
Reposted by Jarod
ARTEFACT Alert! Be very careful when following the “Mito”(??)Tracker…
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
MitoTracker transfers from astrocytes to neurons independently of mitochondria
The neuroprotective transfer of mitochondria from astrocytes to neurons has been primarily investigated by labelling astrocytic mitochondria with the dye MitoTracker. Here we report that MitoTracker transfers to neurons from both astrocytes and astrocyte-conditioned media, independently of mitochondrial transfer. Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer and in other systems in which contact-independent transfer has been observed using mitochondrial dyes. ### Competing Interest Statement The authors have declared no competing interest. MSD (United Kingdom), https://ror.org/004nn4n27, PRJ_20446 DEVINE MSD MRC The Francis Crick Institute, https://ror.org/04tnbqb63, CC2206
www.biorxiv.org
July 9, 2025 at 6:25 AM
ARTEFACT Alert! Be very careful when following the “Mito”(??)Tracker…
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Jarod
It seems that only the science community is noticing that NIH and NSF budgets are cut 40% and 55% in the budget bill, respectively. If you live in Maine, West Va, Pennsylvania, Alabama, or Louisiana, CALL YOUR SENATOR as they could make a difference. See below.
prospect.org/politics/202...
prospect.org/politics/202...
Will the Senate Save NIH?
Rescuing biomedical research is every bit as important as saving Medicaid.
prospect.org
June 29, 2025 at 3:17 AM
It seems that only the science community is noticing that NIH and NSF budgets are cut 40% and 55% in the budget bill, respectively. If you live in Maine, West Va, Pennsylvania, Alabama, or Louisiana, CALL YOUR SENATOR as they could make a difference. See below.
prospect.org/politics/202...
prospect.org/politics/202...
Reposted by Jarod
There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd.
It's not just budgets but research, institutions, expertise, and training the next generation.
It's not just budgets but research, institutions, expertise, and training the next generation.
May 31, 2025 at 4:43 AM
There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd.
It's not just budgets but research, institutions, expertise, and training the next generation.
It's not just budgets but research, institutions, expertise, and training the next generation.
Have you ever loved someone so much you wanted to cure aging?
May 11, 2025 at 7:16 PM
Have you ever loved someone so much you wanted to cure aging?