Jamie Smith
jamiesmith.bsky.social
Jamie Smith
@jamiesmith.bsky.social
PhD student @JHU. Bacterial pathogenesis. she/her 🏳️‍🌈🧫
Reposted by Jamie Smith
Excited to share our lab's newest preprint (strap in if you're excited about metabolism, species differences, or Mtb gene expression): www.biorxiv.org/content/10.1...
Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species
Mycobacterium tuberculosis (Mtb) persists within macrophages, yet how different host species shape bacterial state remains poorly understood. Here, we directly compared the intracellular transcriptome...
www.biorxiv.org
November 17, 2025 at 6:20 AM
Reposted by Jamie Smith
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology
The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.
www.nature.com
October 10, 2025 at 1:24 PM
Reposted by Jamie Smith
Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025
October 3, 2025 at 8:40 PM
Reposted by Jamie Smith
🗓️ Check it out! The full agenda for Black In Microbiology Week 2025 is live. Get all the details here: tinyurl.com/BIMW25 and Pre-register to secure your spot: linktr.ee/BlackInMicro. To help keep #BlackInMicro alive, Donate here: tinyurl.com/GiveBiM (all links in bio)
October 7, 2025 at 7:40 PM
Reposted by Jamie Smith
Reposted by Jamie Smith
Microbiologist & Associate Professor Kim Davis @davislabjhu.bsky.social & her lab team investigate gene expression changes associated with bacterial growth to find markers that predict bacterial survival after antibiotic treatment.

DAVIS LAB
bit.ly/45ZMgxj

2/2

journals.plos.org/plospathogen...
Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility
Author summary Slow-growing bacterial cells generally have reduced antibiotic susceptibility, rendering them difficult to eliminate during antibiotic treatment. However, for many key virulence factors...
journals.plos.org
August 21, 2025 at 4:53 PM
Reposted by Jamie Smith
Celebrated Kate’s PhD thesis defense today! Huge congrats to the new Dr. Cotten and fantastic job on your seminar and defense!! 😀
June 28, 2025 at 1:22 AM
Reposted by Jamie Smith
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !
Staphylococcus aureus exhibits spatiotemporal heterogeneity in Sae activity during kidney abscess development https://www.biorxiv.org/content/10.1101/2025.07.08.663646v1
July 10, 2025 at 1:17 AM
Reposted by Jamie Smith
Big congrats to the new Dr. Cotten @katecotten.bsky.social on the manuscript submission! Preprint is now available on biorxiv, and links a tRNA modification to specific reductions in ribosomal gene expression and antibiotic tolerance. Check it out! 😀
Loss of s2U tRNA modification induces antibiotic tolerance in Yersinia pseudotuberculosis https://www.biorxiv.org/content/10.1101/2025.07.01.662621v1
July 10, 2025 at 1:22 AM
Reposted by Jamie Smith
🎉 Congratulations to @johnshopkinssph.bsky.social & @johnshopkinsmmi.bsky.social PhD graduate Kate Cotten, PhD, who successfully defended her PhD thesis!

Way to go, Kate!

Read more about Kate & other MMI PhD students here
publichealth.jhu.edu/departments/...
July 2, 2025 at 3:56 PM
Reposted by Jamie Smith
#standupforscience2025 DC! Great to feel such a strong sense of community after so many weeks of uncertainty
March 8, 2025 at 12:18 AM
Reposted by Jamie Smith
Nominations are open for the Index of Inspiring Black Scientists! We're building a global resource to celebrate and connect inspiring Black scholars in STEM at all career stages. Nominate someone today! Details: forms.gle/7nq5s2xBENUF...

#InspiringBlackScientists
December 12, 2024 at 5:17 PM
Reposted by Jamie Smith
Happy holidays from the Davis lab!! Had a holiday breakfast this morning with our annual white elephant gift exchange! 🥳🎁 Very thankful to work with this great group of scientists!! 😀
December 18, 2024 at 6:43 PM
Reposted by Jamie Smith
Transgender Day of Remembrance (TDOR) is an annual observance on November 20 that honors the memory of the transgender people whose lives were lost in acts of anti-transgender violence. glaad.org/tdor-memoriam/
November 20, 2024 at 3:09 PM
Reposted by Jamie Smith
New Salmonella Persister cells Review is just out❗️

Rachel Giorgio & Sophie Helaine overview the physiology & clinical implications of antibiotic-recalcitrant Salmonella during infection

- highlighting important knowledge gaps that need to be addressed…

www.nature.com/articles/s41...
Antibiotic-recalcitrant Salmonella during infection - Nature Reviews Microbiology
In this Review, Giorgio and Helaine provide an overview of the physiology of antibiotic-recalcitrant Salmonella enterica during infection, discuss recent insights into the clinical implications of ant...
www.nature.com
November 20, 2024 at 6:35 PM
Reposted by Jamie Smith
Believe it or not, GRC has told me we need more registered applicants or this meeting might not survive! Please don't let that happen if you can afford to attend 🙏
If you're interested in learning about the latest of fundamental mycobacteriology, sign up for #GRCMyco2025! Acceptances will start in September, check out the full program and please RT!
We're live with the program!
www.grc.org/biology-of-m...
November 19, 2024 at 10:46 PM
Reposted by Jamie Smith
November 18 is the International Day of LGBQTIA+ People in STEM! Today more than ever we want to stress the importance of communities, building connections, and raising each other up. Let's keep leaving our mark for the betterment of us all! 🏳️‍⚧️🏳️‍🌈 #QueerinSTEM

prideinstem.org/lgbtstemday/
November 18, 2024 at 8:55 AM
Reposted by Jamie Smith
Today is International Day of LGBTQIA+ People in STEM! We are marking this occasion with our first ever Pride in Microbiology Research Symposium and have a lineup of incredible speakers!

#QueerinSTEM

It's still not too late to register: forms.gle/cE8n7F1688Ns...
November 18, 2024 at 1:23 PM
#MicroSky 🧪🧫🦠
Here's a starter pack of Black Microbiologists. A work in progress as people are migrating over from other platforms. Let me know if you want to be added! go.bsky.app/EcYiqNV
November 17, 2024 at 5:59 PM
Reposted by Jamie Smith
Excited to see many in the bacterial pathogenesis community joining here in the last few weeks, so here's a Starter Pack to help make connections. Reply/DM to be added to this or future Packs. #Microsky go.bsky.app/VH64BaY
November 17, 2024 at 1:46 AM
Reposted by Jamie Smith
It's Transgender Awareness Week (November 13th - November 19th): A time to reflect and learn about the issues that transgender people face, and how we can better support our trans friends and colleagues.

You can learn more here:
Transgender Awareness Week | GLAAD
Each year between November 13 – 19, people and organizations around the country participate in Transgender Awareness Week to help increase understanding about transgender people and the issues…
glaad.org
November 15, 2024 at 4:34 PM
Reposted by Jamie Smith
hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...
Starter packs
BIOLOGY Ecology Macroecology https://go.bsky.app/GBn9pNZ Global ecology https://go.bsky.app/V6tN4cv Trait based ecology and evolution https://go.bsky.app/PThMXeX Invasion biology https://go.b...
docs.google.com
November 11, 2024 at 5:41 PM
Reposted by Jamie Smith
Welcome refugees from X! Follow microbiologists and more in the @binningsingletons.com and Friends Starter Pack!

go.bsky.app/H5k2p2g
October 17, 2024 at 8:53 PM
Reposted by Jamie Smith
November 10, 2024 at 9:46 PM
Reposted by Jamie Smith
Calling all microbiologists! Registration is open for the Mid-Atlantic Microbial Pathogenesis Meeting, February 2-4, 2025.! Abstract deadline is 12/8/2024, but don't wait, filling fast. Check it out at mampm.org.
MAMPM
February 2-4, 2025 Wintergreen Resort, Virginia
mampm.org
November 9, 2024 at 2:20 PM