Irene Miguel-Aliaga
@irenemiguel-aliaga.bsky.social
Eternally asking questions.
Likes guts.
Has guts.
And a lab at the Francis Crick Institute @thecrick.bsky.social
https://www.crick.ac.uk/research/labs/irene-miguel-aliaga
Likes guts.
Has guts.
And a lab at the Francis Crick Institute @thecrick.bsky.social
https://www.crick.ac.uk/research/labs/irene-miguel-aliaga
Pinned
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Pleased to have had a hand in shaping the new edition of Comprehensive Molecular #Insect Science. The insects provided the complexity; the chapter contributors made sense of it www.sciencedirect.com/referencewor...
#Physiology #Reproduction #Neurobiology #Ecology #Immunity #Symbiosis #Endocrinology
#Physiology #Reproduction #Neurobiology #Ecology #Immunity #Symbiosis #Endocrinology
Comprehensive Molecular Insect Science
Comprehensive Molecular Insect Science, Second Edition is a unique resource that provides extensive review articles on contemporary topics in insect s...
www.sciencedirect.com
November 7, 2025 at 10:05 AM
Pleased to have had a hand in shaping the new edition of Comprehensive Molecular #Insect Science. The insects provided the complexity; the chapter contributors made sense of it www.sciencedirect.com/referencewor...
#Physiology #Reproduction #Neurobiology #Ecology #Immunity #Symbiosis #Endocrinology
#Physiology #Reproduction #Neurobiology #Ecology #Immunity #Symbiosis #Endocrinology
Deadline approaching for the EMBO meeting "Molecular and Developmental Biology of Drosophila" 21 – 27 June 2026.
Both new and established PIs welcome.
Apply by Nov 3rd!
meetings.embo.org/event/26-dro...
Both new and established PIs welcome.
Apply by Nov 3rd!
meetings.embo.org/event/26-dro...
Molecular and Developmental Biology of Drosophila
The principal theme of the EMBO Workshop is the Molecular and Developmental Biology of Drosophila. Supported by EMBO over four decades, this will be the 24th biennial “Crete meeting”.
With the a…
meetings.embo.org
October 26, 2025 at 7:41 PM
Deadline approaching for the EMBO meeting "Molecular and Developmental Biology of Drosophila" 21 – 27 June 2026.
Both new and established PIs welcome.
Apply by Nov 3rd!
meetings.embo.org/event/26-dro...
Both new and established PIs welcome.
Apply by Nov 3rd!
meetings.embo.org/event/26-dro...
Come work with us!!
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 10, 2025 at 8:06 PM
Come work with us!!
UK undergrads, apply to this programme for your chance to work with the one and only Dr Amélie Joly!
📢 We are looking for a sandwich student to join the lab of @irenemiguel-aliaga.bsky.social at the @crick.ac.uk for a 12-month placement starting July 2025!
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...
The sex and reproductive plasticity of the intestine
www.crick.ac.uk
September 11, 2025 at 2:35 PM
UK undergrads, apply to this programme for your chance to work with the one and only Dr Amélie Joly!
Reposted by Irene Miguel-Aliaga
Congratulations to @carovinuesa.bsky.social on receiving the 2026 FEBS | @embo.org Women in Science Award.
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
Carola Vinuesa receives FEBS | EMBO Women in Science Award
Carola Vinuesa, Principal Group Leader and Assistant Research Director at the Francis Crick Institute is to receive the 2026 FEBS | EMBO Women in Science Award for her scientific achievements as well ...
www.crick.ac.uk
September 9, 2025 at 3:49 PM
Congratulations to @carovinuesa.bsky.social on receiving the 2026 FEBS | @embo.org Women in Science Award.
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
She is recognised for her scientific achievements and her impact as a role model within the life sciences community.
www.crick.ac.uk/news/2025-09...
Reposted by Irene Miguel-Aliaga
We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS
June 11, 2025 at 8:11 PM
We’re excited to share a new pre-print from the lab! Led by Carmen Ramirez Moncayo and a fantastic collaboration with several groups from across @mrc-lms.bsky.social & @imperialcollegeldn.bsky.social. Interested in #OvarianCancer, #PARPinhibitors or #DrugDistribution? please read on! bit.ly/45lpekS
Reposted by Irene Miguel-Aliaga
Image Analysis job opportunity in the lab of @irenemiguel-aliaga.bsky.social at @crick.ac.uk !
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Postdoctoral Project Research Scientist - Miguel-Aliaga Lab
www.crick.ac.uk
June 18, 2025 at 10:02 AM
Image Analysis job opportunity in the lab of @irenemiguel-aliaga.bsky.social at @crick.ac.uk !
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Reposted by Irene Miguel-Aliaga
A good summary of what's going on. If you have the means, you can donate already to the Cambridge side. If you can spread the word, please do. FlyBase touches every field of bio research: cancer, neurology, development, immunity, genetics, evolution, etc...
www.thetransmitter.org/community/fl...
www.thetransmitter.org/community/fl...
June 6, 2025 at 5:27 AM
A good summary of what's going on. If you have the means, you can donate already to the Cambridge side. If you can spread the word, please do. FlyBase touches every field of bio research: cancer, neurology, development, immunity, genetics, evolution, etc...
www.thetransmitter.org/community/fl...
www.thetransmitter.org/community/fl...
Reposted by Irene Miguel-Aliaga
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
May 14, 2025 at 4:01 PM
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Tomo's take on his recent work with us - Tomo now his own boss at Science Tokyo
Re-growing adult organs: mothers do it best
Tomotsune Ameku from the lab of @irenemiguel-aliaga.bsky.social @crick.ac.uk tells the behind the paper story of their work looking into maternal intestinal growth in mice during reproduction:
thenode.biologists.com/re-growing-a...
Tomotsune Ameku from the lab of @irenemiguel-aliaga.bsky.social @crick.ac.uk tells the behind the paper story of their work looking into maternal intestinal growth in mice during reproduction:
thenode.biologists.com/re-growing-a...
Re-growing adult organs: mothers do it best - the Node
Tomotsune Ameku tells the story behind the paper "Growth of the maternal intestine during reproduction"
thenode.biologists.com
May 1, 2025 at 9:13 PM
Tomo's take on his recent work with us - Tomo now his own boss at Science Tokyo
Reposted by Irene Miguel-Aliaga
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
March 10, 2025 at 2:43 AM
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
Reposted by Irene Miguel-Aliaga
Our latest preprint…Adrien Franchet, Yuhong Jin et al @crick.ac.uk show that circulating glutamine drives brain sparing during nutrient restriction. Great collab with labs of Yaël Grosjean and Ian Gilmore.
#metabolism #Drosophila #neuralstemcells
www.biorxiv.org/content/10.1...
#metabolism #Drosophila #neuralstemcells
www.biorxiv.org/content/10.1...
April 4, 2025 at 7:51 AM
Our latest preprint…Adrien Franchet, Yuhong Jin et al @crick.ac.uk show that circulating glutamine drives brain sparing during nutrient restriction. Great collab with labs of Yaël Grosjean and Ian Gilmore.
#metabolism #Drosophila #neuralstemcells
www.biorxiv.org/content/10.1...
#metabolism #Drosophila #neuralstemcells
www.biorxiv.org/content/10.1...
Reposted by Irene Miguel-Aliaga
⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.
March 20, 2025 at 8:03 AM
⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.
Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, @coxlabkcl.bsky.social, @priscaliberali.bsky.social and Maria Rodriguez-Colman
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:32 PM
Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, @coxlabkcl.bsky.social, @priscaliberali.bsky.social and Maria Rodriguez-Colman
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Reposted by Irene Miguel-Aliaga
Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
journals.biologists.com
March 13, 2025 at 9:13 PM
Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
We stand with our US colleagues during this challenging time
Science transcends borders—setbacks in one nation affect us all
journals.biologists.com/dev/article/...
Reposted by Irene Miguel-Aliaga
My first post in Bluesky and first invited talk as a new PI. Come see how we use in vivo imaging to understand how spatio-temporal changes in metabolism drive responses to oncogenic mutations in the skin. Thanks so much to the organisers for giving me this platform.
Save the Date: In next week's CIBSS seminar, Dr. Anupama Hemalatha (@fmiscience.bsky.social) will discuss metabolic rewiring at the interphase of oncogenesis and homeostasis.
Tuesday, March 18, 2025, 12:00–13:00
Institute of Biology I, Hauptstr. 1
Join in person or via livestream: kurzlinks.de/dkt6
Tuesday, March 18, 2025, 12:00–13:00
Institute of Biology I, Hauptstr. 1
Join in person or via livestream: kurzlinks.de/dkt6
March 15, 2025 at 8:42 AM
My first post in Bluesky and first invited talk as a new PI. Come see how we use in vivo imaging to understand how spatio-temporal changes in metabolism drive responses to oncogenic mutations in the skin. Thanks so much to the organisers for giving me this platform.
Reposted by Irene Miguel-Aliaga
Women in research need the credit & recognition they deserve for the amazing contributions they make.
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards Inspiring Women in Science
Celebrating and supporting the achievements of women in science, and all those who work to encourage girls and young women to engage with STEM subjects and stay in STEM careers around the world.
www.nature.com
March 8, 2025 at 8:24 AM
Women in research need the credit & recognition they deserve for the amazing contributions they make.
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Nature Awards for Inspiring Women in Science are open for applications - take a look 👇🏻 & help spread the word
#WomeninSTEM #AcademicSky 🧪
@natureportfolio.nature.com
www.nature.com/immersive/in...
Reposted by Irene Miguel-Aliaga
Are you a clinician looking for a fully-funded postdoctoral research opportunity? 🩺
Take a look at our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community of clinician scientists.
Apply by 30 April ⤵️ www.crick.ac.uk/careers-and-...
Take a look at our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community of clinician scientists.
Apply by 30 April ⤵️ www.crick.ac.uk/careers-and-...
Postdoctoral clinical fellows
Opportunities for postdoctoral clinicians to consolidate their research experience.
www.crick.ac.uk
March 4, 2025 at 12:11 PM
Are you a clinician looking for a fully-funded postdoctoral research opportunity? 🩺
Take a look at our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community of clinician scientists.
Apply by 30 April ⤵️ www.crick.ac.uk/careers-and-...
Take a look at our postdoctoral career development fellowships for clinicians, and see how you can join our vibrant community of clinician scientists.
Apply by 30 April ⤵️ www.crick.ac.uk/careers-and-...
Reposted by Irene Miguel-Aliaga
Applications for our Future Leaders in Biomedical Sciences scholarships are now open.
These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences.
Learn more and apply. ⬇️
www.crick.ac.uk/careers-and-...
These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences.
Learn more and apply. ⬇️
www.crick.ac.uk/careers-and-...
Future Leaders in Biomedical Sciences Scholarships
Open to candidates of Black or mixed Black heritage only.
www.crick.ac.uk
February 28, 2025 at 10:16 AM
Applications for our Future Leaders in Biomedical Sciences scholarships are now open.
These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences.
Learn more and apply. ⬇️
www.crick.ac.uk/careers-and-...
These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences.
Learn more and apply. ⬇️
www.crick.ac.uk/careers-and-...
Reposted by Irene Miguel-Aliaga
Does what's happening in your gut affect what's happening in your brain?
Researchers at the Crick are continuously learning new things about this complex relationship.
Read more about their work and the gut-brain connection. 👇
www.crick.ac.uk/news/2025-01...
Researchers at the Crick are continuously learning new things about this complex relationship.
Read more about their work and the gut-brain connection. 👇
www.crick.ac.uk/news/2025-01...
Understanding our complex gut brain
Researchers are uncovering the complex connection between your gut and brain.
www.crick.ac.uk
February 6, 2025 at 10:30 AM
Does what's happening in your gut affect what's happening in your brain?
Researchers at the Crick are continuously learning new things about this complex relationship.
Read more about their work and the gut-brain connection. 👇
www.crick.ac.uk/news/2025-01...
Researchers at the Crick are continuously learning new things about this complex relationship.
Read more about their work and the gut-brain connection. 👇
www.crick.ac.uk/news/2025-01...
Small but mighty: multiple Y chromosome contributions to mouse spermatogenesis @lab-turner.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Systematic identification of Y-chromosome gene functions in mouse spermatogenesis
The mammalian Y chromosome is essential for male fertility, but which Y genes regulate spermatogenesis is unresolved. We addressed this by generating 13 Y-deletant mouse models. In Eif2s3y, Uty, and Z...
www.science.org
January 24, 2025 at 9:39 AM
Small but mighty: multiple Y chromosome contributions to mouse spermatogenesis @lab-turner.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
"Rejection of molecular reductionism or determinism does not necessitate a commitment to the idea of biological agency. Researchers need not embrace the agency perspective in order to acknowledge the importance of multi-level complexity, emergence, and downward causation."
Excellent, timely and thought-provoking article by my colleague James DiFrisco @crick.ac.uk : academic.oup.com/jeb/advance-.... I am *almost* persuaded...
Biological agency: a concept without a research program
Abstract. This paper evaluates recent work purporting to show that the “agency” of organisms is an important phenomenon for evolutionary biology to study.
academic.oup.com
January 3, 2025 at 9:52 PM
"Rejection of molecular reductionism or determinism does not necessitate a commitment to the idea of biological agency. Researchers need not embrace the agency perspective in order to acknowledge the importance of multi-level complexity, emergence, and downward causation."
Excellent, timely and thought-provoking article by my colleague James DiFrisco @crick.ac.uk : academic.oup.com/jeb/advance-.... I am *almost* persuaded...
Biological agency: a concept without a research program
Abstract. This paper evaluates recent work purporting to show that the “agency” of organisms is an important phenomenon for evolutionary biology to study.
academic.oup.com
January 3, 2025 at 9:50 PM
Excellent, timely and thought-provoking article by my colleague James DiFrisco @crick.ac.uk : academic.oup.com/jeb/advance-.... I am *almost* persuaded...
Reposted by Irene Miguel-Aliaga
We have a new opening! Amazing environment colleagues and facility! Join us!
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 5:49 PM
We have a new opening! Amazing environment colleagues and facility! Join us!